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Effectiveness and safety of jinshuibao capsules(金水宝胶囊)in treatment of residual cardiopulmonary symptoms in convalescent patients of coronavirus disease 2019:a pilot randomized,double-blind,placebo-controlled clinical trial

引用

Journal of Traditional Chinese Medicine 2023年第1期43卷 134-139页

作者： ZHANG Yuehong DONG Dandan YAN Youqin ZHANG Hao WANG Guangli ZHOU Wei LI Wei QIU Li LI Tingming LIU Quan XIA Ping MAO Lina YANG Danlin YANG Lu LIAN Fengmei TONG Xiaolin BA Yuanming Department of Endocrinology Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China Department of Infectious Diseases Wuhan No.7 HospitalWuhan 430071China Department of Electrocardiograms Hubei Provincial Hospital of Traditional Chinese MedicineWuhan 430061China Department of Respiratory Hubei Provincial Hospital of Traditional Chinese MedicineWuhan 430061China Department of Nephrology Hubei Provincial Hospital of Traditional Chinese MedicineWuhan 430061China Department of Orthopaedics Wuhan No.1 HospitalWuhan 430061China Department of Respiratory Wuhan No.1 HospitalWuhan 430061China

OBJECTIVE:To evaluate the effectiveness and safety of jinshuibao capsules(金水宝胶囊),a Traditional Chinese Medicine(TCM),in the treatment of residual cardiopulmonary symptoms in convalescent corona virus disease 2019(COVID-19)***:A total of 200 participants with COVID-19 in convalescence phase were randomly assigned into two groups at a 1:1 ratio in this multicenter randomized,double-blind,placebo-controlled *** group received jinshuibao capsules,and the other received *** patients were followed up at one and two weeks of *** symptoms(dry cough,shortness of breath,sweating,chest tightness and palpitation)improvement rates and full recovery rates were ***:All baseline characteristics were comparable between the two *** two weeks of treatment,symptom improvement rates for dry cough(74.00%vs 50.00%,P=0.015),shortness of breath(78.95%vs 46.15%,Pjinshuibao group compared with the control ***,jinshuibao capsules treatment also displayed more satisfactory full recovery rates of all five symptoms(dry cough 58.00%vs 19.57%,shortness of breath 18.95%vs 7.69%,sweating 36.00%vs 19.72%,chest tightness 32.94%vs 13.95%,and palpitation 48.75%vs 29.11%)in participants with COVID-19 in convalescence phase compared with the control group(Pjinshuibao capsules have the potential to improve residual cardiopulmonary symptoms in convalescent COVID-19 patients,with few adverse events.

关键词： COVID-19 convalescence signs and symptoms randomized controlled trial jinshuibao capsules

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Effects of Feiwei granules in the treatment of idiopathic pulmonary fibrosis:a randomized and placebo-controlled trial

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Journal of Traditional Chinese Medicine 2016年第4期36卷 427-433页

作者： Yu Yang Sun Zengtao Shi Liqing Zhang Yanping Zhou Zhaoshan Zhang Shunan Chao Enxiang Graduate School Beijing University of Chinese Medicine Department of Respiratory Medicine the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine Respiratory Pyrexia Department Dongfang Hospital Affiliated to Beijing University of Chinese Medicine Department of Respiratory Medicine Xiyuan Hospital of China Academy of Traditional Chinese Medicine Department of Respiratory Medicine Qingdao Hiser Medical Group Department of Respiratory Disease of Traditional Chinese Medicine China-Japan Friendship Hospital

OBJECTIVE:To document the therapeutic effect of Feiwei granules(FGs) for idiopathic pulmonary fi brosis(IPF).METHODS:One hundred cases with IPF were randomized into the treatment group(80) and control group(20).Both groups were given basic treatment with *** treatment group was given FGs,and the control group was given jinshuibao capsules(JCs).Treatment lasted for 6 *** Medical Research Council Dyspnea Scale(MRCDS),the Saint George's Hospital Respiratory Questionnaire(SGHRQ),pulmonary function,the Traditional Chinese Medicine Syndrome Score(TCMSS),6-min walking test(6MWT) and blood gas analyses were recorded before the study as well as3 months and 6 months after ***:FGs showed greater efficacy than the control in certain parameters between before the study and 6 months,and between 3 months and 6months,in the MRCDS,some indicators in the SGHRQ,and the *** were no significant differences between the treatment group and control group in the remainder of the indices *** the treatment group,there were significant differences in before and after treatment in the MRCDS,SGHRQ,TCMSS and ***:FGs were similar to JCs for IPF treatment.

关键词： Idiopathic pulmonary fibrosis Dys pnea Surveys and questionnaires 6-min walking test Feiwei granules jinshuibao capsules Random ized controlled trial

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