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小儿KDP全凭静脉全麻1,000例临床应用

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中华小儿外科杂志 1987年第1期9卷 9-10页

作者：陈耕垦陈锦娥林惠珍郭永正金友松张文萱福建医学院附属协和医院麻醉科

本文采用氯胺酮200mg,安定20mg,普鲁卡因4 g加10%葡萄糖液200ml的复合液,用于3天～14岁小儿手术1,000例.静滴速率10～25滴/分,麻醉过浅可追加少量的硫喷妥钠或安定静注.术毕5～15分钟清醒.作者认为该麻醉能充分发挥三者的协同作用;减轻... 详细信息

本文采用氯胺酮200mg,安定20mg,普鲁卡因4 g加10%葡萄糖液200ml的复合液,用于3天～14岁小儿手术1,000例.静滴速率10～25滴/分,麻醉过浅可追加少量的硫喷妥钠或安定静注.术毕5～15分钟清醒.作者认为该麻醉能充分发挥三者的协同作用;减轻副反应;具有速效、短效、强镇静、容易调节、保持自主呼吸的优点,且大多数勿需常规气管内插管.是较好的小儿全麻方法之一.

关键词：小儿手术 KDP 静脉全麻临床应用 endotracheal intubation total intravenous anaesthesia general anaesthesia blood pressure understanding action 气管内插管减轻副反应 effective analgesia 自主呼吸协同作用普鲁卡因葡萄糖液麻醉硫喷妥钠

Effects of Bai-Hua-Qian-Hu,a Chinese Traditional Herb,on Coronary Blood Flow and Some Cardiovascular Indices

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中国医科大学学报 1989年第S2期18卷 51-53页

作者：常天辉张克义 Department of Pharmacology China Medical University

To study the effects of Bai-Hua-Qian-Hu on cardiovascular system,emphasis was put on the research of Bai-Hua-Qian-Hu extracted with water and alcohol on coronary flow and some cardiovascular indices in both isolated preparations and intact normal animals. The results showed that extract obtained with water and alcohol （Pd-wa） increased coronary flow in isolated rabbit heart and in the anaesthetized cats, Pd-wa antagonised the strip contraction either in canine coronary artery or in rabbit aorta, and increased myocardial nutrient blood flow in mice, The values of LD50 by peritoneal and intravenous injection proved that Pd-wa was very safe.

关键词： alcohol cardiovascular rabbit aorta intravenous peritoneal preparations Blood canine nutrient

MAGNETIC DISK APPLIED ON NEIGUAN POINT FOR PREVENTION AND TREATMENT OF CISPLATIN-INDUCED NAUSEA AND VOMITING

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Journal of Traditional Chinese Medicine 1991年第3期11卷 181-183页

作者：刘少翔陈志峰侯浚王济民王俊茹张秀云 Hebei Provincial Institute of Oncology Affiliated Hospital Hebei Provincial Academy of Medical Sciences Qiaodong District Hospital ShijiazhuangHebei Province

Cisplatin is commonly used in the treat-ment of cancers,but at the same time oftencauses side-effects like severe nausea andvomiting,which cannot be prevented ortreated satisfactorily with ordinary westernor traditional Chinese drugs,thus hinderingthe chemotherapy from being carried *** tried several methods to tack-le the situation,and found that placing a flatpiece of magnetic disk on Neiguan pointhad a remarkable *** following is areport of our work.

关键词： Cisplatin nausea tried chemotherapy ordinary remarkable vomiting intravenous markedly courses

32磷标记供体白细胞静脉注射预处理对兔同种皮肤移植存活的延长作用

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中华器官移植杂志 1984年第2期5卷 54-57,后插1页

作者：刘长年马腾骧王梓清张欣李玉芝刘耀晨天津医学院第二附属医院同位素室天津医学院第二附属医院检验科天津市泌尿外科研究所

TREATMENT OF PRIMARY THROMBOCYTOPENIC PURPURA BY MODIFIED MINOR DECOCTION OF BUPLEURUM

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Journal of Traditional Chinese Medicine 1995年第2期15卷 96-98页

作者：段彧赵秀勤徐秀琴杨景霞李贞祥 Department of Traditional Chinese Medicine People's Hospital of Langfang CityHebei Province 102800

Primary thrombocytopenic purpura is ahemorrhagic disease induced by rapid de-struction of blood platelets throughautoimmunity. The authors treated 10 casesof the disease with modified MinorDecoction of Bupleurum with ... 详细信息

关键词： Bupleurum Radix struction decoction thrombo intravenous uterine bleeding Codonopsis gingival

TREATMENT OF HISTAMINE HEADACHE WITH ACUPUNCTURE ON DAZHUI(DU 14)

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Journal of Traditional Chinese Medicine 1991年第4期11卷 256-257页

作者：李一清 Changchun College of Traditional Chinese Medicine Jilin Province

Histamine headache is refractory *** author treated 2 cases withsuccess and reported in the following is oneof the cases:*** ××,a man of 38 years,wasadmitted to the ward on Dec.8,1987.

关键词： refractory headache DU 14 sensation nerves needle intravenous tired nausea lumbar

A NEW ANIMAL MODEL OF CORONARY THROMBOSIS AND EFFECTS OF ANTITHROMBOTIC AGENTS

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Chinese Medical Journal 1995年第5期 52-54页

作者：张维东王朋陈湛范亚明 AnzhenHospital

The model was established in male rabbits with experimental atherosclerosis, which was induced by diet cholesterol (0.5 g per day for 8 weeks), by means of intravenous injection of one unit of pituitrin (P.P.). To evaluate the effects of aspirin, heparin and viper venom (VV) on this model, 26 male rabbits were divided randomly into four groups: group A (GA) as control, group B (GB) treated with heparin (10mg, i.v.), group C (GC) with VV (0.08 arginine esterase activity units), group D (GD) with both heparin and VV. Aspirin (30 mg) was given orally before experiment. The results showed that the rate of coronary thrombosis was 11.26% in GA, 8.10% in GB, 9.17% in GC, and 7.56% in GD respectively. The difference between each of three treated groups and the control one was significant (P< 0.005, 0.05, 0.001, respectively). Such a difference can also be found between GA and that without oral aspirin (11.26% vs 16.39%, P<0.001). The beneficial effects of heparin and VV may be due to their inhibitory effects

关键词： heparin Aspirin intravenous cholesterol arginine aspirin venom esterase minutes

A comparative study of pharmacokinetics and pharmacodynamics of vecuronium in children and adults

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Chinese Medical Journal 1998年第1期111卷 84-85页

作者：薛富善刘青华邹勤罗来葵 China 100041

ＡｃｏｍｐａｒａｔｉｖｅｓｔｕｄｙｏｆｐｈａｒｍａｃｏｋｉｎｅｔｉｃｓａｎｄｐｈａｒｍａｃｏｄｙｎａｍｉｃｓｏｆｖｅｃｕｒｏｎｉｕｍｉｎｃｈｉｌｄｒｅｎａｎｄａｄｕｌｔｓＸｕｅＦｕｓｈａｎ薛富善，ＬｉｕＱｉｎｇｈｕａ... 详细信息

ＡｃｏｍｐａｒａｔｉｖｅｓｔｕｄｙｏｆｐｈａｒｍａｃｏｋｉｎｅｔｉｃｓａｎｄｐｈａｒｍａｃｏｄｙｎａｍｉｃｓｏｆｖｅｃｕｒｏｎｉｕｍｉｎｃｈｉｌｄｒｅｎａｎｄａｄｕｌｔｓＸｕｅＦｕｓｈａｎ薛富善，ＬｉｕＱｉｎｇｈｕａ刘青华，ＺｏｕＱｉｎ邹勤ａｎｄＬｕ...

关键词： Adolescent Adult Age Factors Anesthesia intravenous Child Child Preschool Comparative Study Female Humans Infant Male Middle Aged Neuromuscular Nondepolarizing Agents Research Support Non-U.S. Gov't Surgery Plastic Vecuronium Bromide

Pharmacokinetic behaviors and oral bioavailability of oridonin in rat plasma

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Acta Pharmacologica Sinica 2006年第12期27卷 1642-1646页

作者： Wen XU~2 Jin SUN~2 Ting-ting ZHANG~2 Bo MA~2 Sheng-miao CUI~3 Da-wei CHEN~2 Zhong-gui HE~(2,4)2 Department of Pharmaceutics,School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China 3 Department of Pharmacy,Guangdong Pharmaceutical University,Guangzhou 510006,China DepartmentofPharmaceutics SchoolofPharmacyShenyangPharmaceuticalUniversityShenyang110016China DepartmentofPharmacy GuangdongPharmaceuticalUniversityGuangzhou510006China

Aim:To study the intravenous and oral pharmacokinetic behavior of oridonin andits extent of absolute oral bioavailability in ***:Oridonin was adminis-tered to rats via iv(5,10 and 15 mg/kg),po(20,40 and 80 mg/kg)or ip administra-tion(10 mg/kg).The concentrations of oridonin in rat plasma were determined bya high performance liquid chromatography with electrospray ionization mass spec-trometric detection(HPLC/ESI-MS)method and the pharmacokinetic parameterswere determined by non-compartmental ***:The plasma concen-tration of oridonin after intravenous administration decreased polyexponentially,and the pharmacokinetic parameters of oridonin were dose-independent withinthe examined *** was absorbed rapidly after oral gavage with a t(max)ofless than 15 min;the extent of absolute bioavailability of oridonin following oraladministration was 4.32%,4.58% and 10.8%.The extent of absolute bioavailabilityof oridonin following intraperitoneal administration was 12.6%.Conclusion:Firstorder rate pharmacokinetics were observed for oridonin within the range of ivdoses,while the extent of absolute oral bioavailability was rather low and *** low and dose-dependent extent of oral bioavailability may be dueto the saturation of first-pass effects.

关键词： oridonin pharmacokinetics intravenous oral bioavailability intraperitoneal injections rats