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intracranial malignant solitary fibrous tumor metastasized to the chest wall:A case report and review of literature

World Journal of Clinical Cases 2020年第20期8卷 4844-4852页

作者： Daisuke Usuda Shinya Yamada Toshihide Izumida Ryusho Sangen Toshihiro Higashikawa Ken Nakagawa Masaharu Iguchi Yuji Kasamaki Department of General Medicine Kanazawa Medical University Himi Municipal HospitalHimi-shi 935-8531Toyama-kenJapan Department of Infectious Diseases Kanazawa Medical UniversityUchinadamachi 920-0293Ishikawa-kenJapan Department of Respiratory Medicine Kanazawa Medical University Himi Municipal HospitalHimi-shi 935-8531Toyama-kenJapan Department of Geriatric Medicine Kanazawa Medical University Himi Municipal HospitalHimi-shi 935-8531Toyama-kenJapan

BACKGROUND solitary fibrous tumor(SFT)is a rare fibroblastic mesenchymal neoplasm that affects spindle cell soft tissues with broad-spectrum biological behavior;it is predominantly benign,and rarely *** occurs mainly in the tissue structure of the serosa in the pleura and the thorax,and can be found throughout the body,though extra-thoracic localization,including the cephalic region,is *** reported the first case of intracranial malignant SFT metastasized to the chest *** SUMMARY An 81-year-old Japanese man was referred to our hospital due to progressive gait disturbance and appetite *** medical history included partial resection due to brain tumor,four times,and 50-Gray radiation therapy at another hospital,starting when he was 74 years *** unenhanced head computed tomography(CT)scan revealed an 8 cm×5.1 cm×6.5 cm mixed-density mass at the left frontal lobe,accompanying a midline shift,and an unenhanced chest-abdomen CT scan revealed a 6 cm×4.1 cm×6.5 cm low-density mass in the left chest wall.A CT-guided percutaneous lung biopsy was performed,and the pathological findings were SFT corresponding to brain ***,the correct diagnosis of his brain tumor in history of past illness revealed to be SFT,and the unremovable tumor,namely present brain lesions enlarged and metastasized to the chest *** established a definitive diagnosis of intracranial malignant SFT metastasized to the chest *** notified him and his family of the disease,and offered palliative *** passed away on the 29 th hospital *** This case suggests the need for careful,detailed examination,and careful followup when encountering patients presenting with a mass.

关键词： solitary fibrous tumor intracranial malignant solitary fibrous tumor Metastasized chest wall tumor Cluster of differentiation 34 STAT6 Case report

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