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Traditional craniotomy versus current minimally invasive surgery for spontaneous supratentorial intracerebral haemorrhage:A propensity-matched analysis

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World Journal of Radiology 2024年第8期16卷 317-328页

作者： Zhen-Kun Xiao Yong-Hong Duan Xin-Yu Mao Ri-Chu Liang Min Zhou Yong-Mei Yang Hengyang Key Laboratory of Hemorrhagic Cerebrovascular Disease Department of NeurosurgeryHengyang Medical SchoolUniversity of South ChinaHengyang 421000Hunan ProvinceChina Department of Anatomy Hengyang Medical SchoolUniversity of South ChinaHengyang 421000Hunan ProvinceChina

BACKGROUND Minimally invasive surgery(MIS)and craniotomy(CI)are the current treatments for spontaneous supratentorial cerebral haemorrhage(SSTICH).AIM To compare the efficacy and safety of MIS and CI for the treatment of *** Clinical and imaging data of 557 consecutive patients with SSTICH who underwent MIS or CI between January 2017 and December 2022 were retrospectively *** patients were divided into two subgroups:The MIS group and CI *** score matching was performed to minimise case selection *** primary outcome was a dichotomous prognostic(favourable or unfavourable)outcome based on the modified Rankin Scale(mRS)score at 3 months;an mRS score of 0–2 was considered *** In both conventional statistical and binary logistic regression analyses,the MIS group had a better *** outcome of propensity score matching was unexpected(odds ratio:0.582;95%CI:0.281–1.204;P=0.144),which indicated that,after excluding the interference of each confounder,different surgical modalities were more effective,and there was no significant difference in their *** Deciding between MIS and CI should be made based on the individual patient,considering the hematoma size,degree of midline shift,cerebral swelling,and preoperative Glasgow Coma Scale score.

关键词： Cerebral haemorrhage intracerebral haemorrhage Minimally invasive surgery Craniotomy Propensity-matched analysis

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Association of Satellite Sign with Postoperative Rebleeding in Patients Undergoing Stereotactic Minimally Invasive Surgery for Hypertensive intracerebral haemorrhage

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Current Medical Science 2021年第3期41卷 565-571页

作者： Ajith Bemardin Raj Li-fei LIAN Feng XU Guo LI Shan-shan HUANG Qi-ming LIANG Kai LU Jian-ling ZHAO Fu-rong WANG Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

There are few studies regarding imaging markers for predicting postoperative rebleeding after stereotactic minimally invasive surgery(MIS)for hypertensive intracerebral haemorrhage(ICH),and little is known about the relationship between satellite sign on computed tomography(CT)scans and postoperative rebleeding after *** study aimed to determine the value of the CT satellite sign in predicting postoperative rebleeding in patients with hypertensive ICH who undergo stereotactic *** retrospectively examined and analysed 105 patients with hypertensive ICH who underwent standard stereotactic MIS for hematoma evacuation within 72 h following *** rebleeding occurred in 14 of 65(21.5%)patients with the satellite sign on baseline CT,and in 5 of the 40(12.5%)patients without the satellite *** diiTerence was statistically *** and negative values of the satellite sign for predicting postoperative rebleeding were 21.5%and 87.5%,*** logistic regression analysis verified that baseline ICH volume and intraventricular rupture were independent predictors of postoperative *** conclusion,the satellite sign on baseline CT scans may not predict postoperative rebleeding following stereotactic MIS for hypertensive ICH.

关键词： intracerebral haemorrhage minimally invasive surgery satellite sign computed tomography postoperative rebleeding

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丰富环境在脑卒中治疗中的作用(英文)

丰富环境在脑卒中治疗中的作用(英文)

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中国康复医学会运动疗法分会第十一届全国康复学术大会学术会议

作者：姜从玉华山医院

目的:To determine whether there is a difference between patients with a cerebral infarction and those with an intracerebral haemorrhage with respect to the development of independence in activities of daily living over the first six months post-stroke.方法:Patients after first-ever stroke who were enrolled at the moment of possessing stable vital signs in the past one *** study had a multi-center,randomized controlled and prospective clinical trial design and measurements took place at admission,1,3,and 6 months *** relationship between the

关键词： the standardized tertiary reha cerebrovascular accident cerebral infarction intracerebral haemorrhage activities of daily living

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Phase Ⅰ/Ⅱ randomized controlled trial of autologous bone marrow-derived mesenchymal stem cell therapy for chronic stroke

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World Journal of Stem Cells 2017年第8期9卷 133-143页

作者： Kam Sze Tsang Chi Ping Stephanie Ng Xian Lun Zhu George Kwok Chu Wong Gang Lu Anil Tejbhan Ahuja Ka Sing Lawrence Wong Ho Keung Ng Wai Sang Poon Department of Surgery the Chinese University of Hong Kong Department of Anatomical and Cellular Pathology the Chinese University of Hong Kong Department of Imaging and Interventional Radiology the Chinese University of Hong Kong Department of Medicine and Therapeutics the Chinese University of Hong Kong

AIM To examine the safety and efficacy of mesenchymal stem cell(MSC) therapy for intracerebral haemorrhage with neurological dysfunctions for a *** MSC were ex vivo expanded from 29 mL(17-42 mL) autologous bone marrow. Patients were randomized to have two intravenous injections of autologous MSC or placebos in four weeks apart. Neurological functions and clinical outcomes were monitored before treatment and at 12^(th), 16^(th), 24^(th), 36^(th) and 60^(th) week upon completion of^(th)e treatment. RESULTS A mean of 4.57 × 10~7(range: 1.43 × 10~7-8.40 × 10~7) MSC per infusion was administered accounting to 8.54 × 10~5(2.65 × 10~5-1.45 × 10~6) per kilogram body weight in two occasions. There was neither adverse event at time of administration nor sign of de novo tumour development among patients after monitoring for a year post MSC therapy. Neuro-restoration and clinical improvement in terms of modified Barthel index, functional independence measure and extended Glasgow Outcome Scale were evident among patients having MSC therapy compared to patients receiving placebos. CONCLUSION Intravenous administration of autologous bone marrowderived MSC is safe and has the potential of improving neurological functions in chronic stroke patients with severe disability.

关键词： Stroke intracerebral haemorrhage Central nervous system Mesenchymal stem cells Cell therapy

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