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Effect of Active Dried Yeast on intestine development,Intestinal Flora and Serum Cholesterol Mass Concentration of Quails

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Animal Husbandry and Feed Science 2012年第3期4卷 121-124页

作者： ZHANG Ai-wu JU Gui-chun XUE Jun Chinese Medicine Materials College Jilin Agricultural University China National Group of Traditional & Herbal Medicine

[ Objective] The experiments aimed to investigate the effect of dietary active dried yeast on intestine development, intestinal flora and serum cholesterol mass concentration of quails. [ Method] One-day-old 180 quails were randomly divided into 4 groups, 3 repetitions, each with 15 quails. Control group was fed with basic dietary, while experimental groups were added with 0.6, 1,2 g/kg active dried yeast respectively in basic dietary, [ Result] Addition of active dried yeast had little effect on quails＇ intestine development（ P 〉0.05）. With the increasing adding amount active dried yeast, the number of colibacillus decreased significantly （P 〈0.05） while lactobacillus content increasing sharply （P 〈 0.05）. Dietary with 1 and 2 g/kg active dried yeast can significantly decrease the mass concentration of cholesterol in serum （ P 〈 0.05）. [ Conclusion ] Adding active dried yeast in feed can decrease the number of colibacillus while increasing lactobacillus content in intestinal tract of quails, also can low serum cholesterol mass concentration.

关键词： Quails Active dried yeast intestine development Colibacillus Lactobacillus Serum cholesterol

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Cdx1b protects intestinal cell fate by repressing signaling networks for liver specification

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Journal of Genetics and Genomics 2022年第12期49卷 1101-1113页

作者： Qingxia Jin Yuqi Gao Shimin Shuai Yayue Chen Kaiyuan Wang Jun Chen Jinrong Peng Ce Gao College of Animal Sciences Zhejiang UniversityHangzhouZhejiang 310058China Department of Human Cell Biology and Genetics School of MedicineSouthern University of Science and TechnologyShenzhenGuangdong 518055China College of Life Sciences Zhejiang UniversityHangzhouZhejiang 310058China

In mammals,the expression of the homeobox family member Cdx2/CDX2 is restricted within the intestine.Conditional ablation of the mouse Cdx2 in the endodermal cells causes a homeotic transformation of the intestine towards the esophagus or gastric fate.In this report,we show that null mutants of zebrafish cdx1b,encoding the counterpart of mammalian CDX2,could survive more than 10 days post fertilization,a stage when the zebrafish digestive system has been well developed.Through RNA sequencing(RNA-seq)and single-cell sequencing(sc RNA-seq)of the dissected intestine from the mutant embryos,we demonstrate that the loss-of-function of the zebrafish cdx1b yields hepatocyte-like intestinal cells,a phenotype never observed in the mouse model.Further RNA-seq data analysis,and genetic double mutants and signaling inhibitor studies reveal that Cdx1b functions to guard the intestinal fate by repressing,directly or indirectly,a range of transcriptional factors and signaling pathways for liver specification.Finally,we demonstrate that heat shock-induced overexpression of cdx1b in a transgenic fish abolishes the liver formation.Therefore,we demonstrate that Cdx1b is a key repressor of hepatic fate during the intestine specification in zebrafish.

关键词： Cdx1b CDX2 Hhex intestine development Liver development Prox1a Zebrafish

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Effect of glutamine dipeptide on growth,intestine development and immunity of juvenile mirror carp(Cyprinus Carpio L.)

Effect of glutamine dipeptide on growth,intestine developmen...

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低碳经济与高效养殖——第六次全国饲料营养学术研讨会暨动...

作者： Xu Qi-You~1,Zhu Qing~2,Xu Hong~1,Wang Chang-An~1,Sun Da-Jiang~1 (Heilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences,Harbin 150070,China 2 Animal Science and Technology College of Northeast Agricultural University,Harbin 150030,China)

Glutamine(Gln) is the main energy for some rapid divided cells,and it plays important roles in maintaining the structure and function of intestine immune system.The effect of exogenous supplementation of Ala-Gln on intestine development and immune functions of juvenile German mirror carp(Cyprinus carpio L.) was evaluated.Glutamine(Gln) is the main energy for some rapid divided cells,and it plays important roles in maintaining the structure and function of intestine immune system.The effect of exogenous supplementation of Ala-Gln on intestine development and immune functions of juvenile German mirror carp(Cyprinus carpio L.) was evaluated.

关键词： alanyl-glutamine mirror carp growth intestine development immune function

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