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Animal Nutrition 2023年第4期15卷 420-429页

作者： Changyi Shuai Daiwen Chen Bing Yu Yuheng Luo Ping Zheng Zhiqing Huang Jie Yu Xiangbing Mao Hui Yan Jun He Institute of Animal Nutrition Sichuan Agricultural UniversitySichuan ProvinceChengdu611130China Key Laboratory of Animal Disease-resistant Nutrition Sichuan ProvinceChengdu611130China

To explore the effects of fermented rapeseed meal(FRSM)on growth performance and intestinal health,a total of 30 growing pigs were randomly allotted to three treatments consisting of corn-soybean meal diet(CSD),rapeseed meal diet(RSD),and fermented rapeseed meal diet(FRSD).Results showed that compared with RSD,FRSD feeding increased the average daily gain and final body weight in pigs(Pintestinal epithelium(Pintestinal health in growing pigs,and the results may also help develop novel protein

关键词： Fermented rapeseed meal Growing pigs Growth performance Nutrient digestibility intestinal health

Tannic acid extracted from gallnut prevents post-weaning diarrhea and improves intestinal health of weaned piglets

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Animal Nutrition 2021年第4期7卷 1078-1086页

作者： Yanyan Song Yong Luo Bing Yu Jun He Ping Zheng Xiangbing Mao Zhiqing Huang Junqiu Luo Yuheng Luo Hui Yan Quyuan Wang Huifen Wang Daiwen Chen Jie Yu Animal Nutrition Institute Sichuan Agricultural UniversityKey Laboratory of Animal Disease-Resistance NutritionSichuan ProvinceChengdu611130China Departments of Traditional Chinese Medicine Sichuan Academy of Medical SciencesSichuan Provincial People's HospitalChengdu610031China

This experiment was conducted to evaluate the effects of different levels of tannic acid(TA)on growth performance,diarrhea rate,nutrient digestibility and intestinal health in weaned piglets.A total of 180 weaned piglets(Duroc×Landrace×Yorkshire,24 d of age,initial average BW=7.77±0.17 kg)were allotted to 5 groups(6 pigs/pen and 6 replicates/group)in a randomized complete block design according to their gender and body *** were fed a basal diet,or the basal diet supplemented with 0.05%,0.1%,0.2%or 0.4%TA for 28 *** supplementary levels of TA in the diets were obtained by adding tannalbin containing 51%TA and 40.17%*** results showed that,compared with the CON group,dietary TA did not affect ADFI,ADG or F:G,and linearly reduced(Pintestinal health of weaned piglets,and the appropriate level of TA supplementation woul

关键词： Tannic acid Weaned piglet Post-weaning diarrhea intestinal health

intestinal microbiota and its interaction to intestinal health in nursery pigs

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Animal Nutrition 2022年第1期8卷 169-184页

作者： Marcos Elias Duarte Sung Woo Kim Department of Animal Science North Carolina State UniversityRaleighNC27695United States

The intestinal microbiota has gained increased attention from researchers within the swine industry due to its role in promoting intestinal maturation,immune system modulation,and consequently the enhancement of the health and growth performance of the *** review aimed to provide updated scientific information on the interaction among intestinal microbiota,dietary components,and intestinal health of *** small intestine is a key site to evaluate the interaction of the microbiota,diet,and host because it is the main site for digestion and absorption of nutrients and plays an important role within the immune *** diet and its associated components such as feed additives are the main factors affecting the microbial composition and is central in stimulating a beneficial population of *** microbiotaehost interaction modulates the immune system,and,concurrently,the immune system helps to modulate the microbiota *** direct interaction between the microbiota and the host is an indication that the mucosa-associated microbiota can be more effective in evaluating its effect on health *** was demonstrated that the mucosa-associated microbiota should be evaluated when analyzing the interaction among diets,microbiota,and *** addition,supplementation of feed additives aimed to promote the intestinal health of pigs should consider their roles in the modulation of mucosa-associated microbiota as biomarkers to predict the response of growth performance to dietary interventions.

关键词： intestinal health Mucosa-associated microbiota Nursery pig

Effects of tannic acid on the immunity and intestinal health of broiler chickens with necrotic enteritis infection

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Journal of Animal Science and Biotechnology 2023年第6期14卷 2454-2473页

作者： Huiping Xu Jianyang Fu Yimeng Luo Peng Li Bochen Song Zengpeng Lv Yuming Guo Department of Animal Nutrition and Feed Science State Key Laboratory of Animal NutritionCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Department of Animal Science Shandong Agricultural UniversityTaian 271018China

Background In broiler chickens,necrotic enteritis(NE)infection can reduce production *** acid has shown great potential as a treatment of NE in ***,the appropriate dosage of tannic acid in NE of broilers and the improvement effect on intestinal health are not very *** this study,we aimed to investigate the effects of different doses of tannic acid on the production performance,immunity,and intestinal health of broilers by constructing an NE model with *** infection and determining the appropriate dosage of tannic acid with regard to *** Challenged birds showed significant reduction in body weight,villus height,and the ratio of villus height to crypt depth(Pintestinal lesion score,and crypt depth(Pintestinal barrier genes and growth performance and reduced serum zonulin and endotoxin levels(Pintestinal barrier a

关键词： Broiler chicken Immunity intestinal health Necrotic enteritis Tannic acid

Effects of different amino acid levels and a carvacrol-thymol blend on growth performance and intestinal health of weaned pigs

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Journal of Animal Science and Biotechnology 2022年第5期13卷 1428-1439页

作者： Yanan Wang Zhipeng Yang Yuanfei Zhou Jiajian Tan Haiqing Sun Defa Sun Yuyun Mu Jian Peng Hongkui Wei Department of Animal Nutrition and Feed Science College of Animal Science and TechnologyHuazhong Agricultural UniversityWuhan 430070China Guangxi Yangxiang Co. LtdGuigang 537000China Novus International Trading(Shanghai)Co.Ltd Shanghai 200080China The Cooperative Innovation Center for Sustainable Pig Production Wuhan 430070China

Background:Over the past years,antibiotic growth promoter had been restricted in animal husbandry production in many countries because of antimicrobial resistance and foodborne antibiotic ***,the problems of poor intestinal health and low growth efficiency of piglets have not been solved completely in an antibiotic-free diet,and it is urgent to explore alternatives to antimicrobial growth ***:Here,a total of 532 weaned pigs were assigned to one of 4 treatments,the low amino acid(AA)level diet(d 1 to d 14 is 1.35%,d 15 to d 42 is 1.25%)(Low AA),the low AA level diet supplementation with a carvacrol-thymol blend(50 mg carvacrol and 50 mg thymol/kg of diet)(CB)(Low AA+CB),the high AA level diet(d 1 to d 14 is 1.50%,d 15 to d 42 is 1.40%)(High AA),and the high AA level diet supplementation with a CB(High AA+CB),*** we measured growth performance and intestinal health indicators of weaned ***:Results showed that high AA level significantly reduced plasma urea nitrogen,plasma Interleukin-6(IL-6)and fecal lipocalin-2 contents(Pintestinal ***:Th

关键词： Amino acids Antioxidant capacity Carvacrol and thymol intestinal health Plant extracts Weaned pigs

Essential oils improve nursery pigs'performance and appetite via modulation of intestinal health and microbiota

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Animal Nutrition 2024年第1期16卷 174-188页

作者： Bi-Chen Zhao Tian-Hao Wang Jian Chen Bai-Hao Qiu Ya-Ru Xu Jin-Long Li College of Veterinary Medicine Northeast Agricultural UniversityHarbin150030China Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine Northeast Agricultural UniversityHarbin150030China Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment Northeast Agricultural UniversityHarbin150030China

Optimal intestinal health and functionality are essential for animal health and performance,and simultaneously intestinal nutrient transporters and intestinal peptides are also involved in appetite and feed intake control *** the potential of essential oil(EO)in improving animal performance and improving feed palatability,we hypothesized that dietary supplementation of cinnamaldehyde and carvacrol could improve performance and appetite of nursery pigs by modulating intestinal health and ***(100 mg/kg),carvacrol(100 mg/kg),and their mixtures(including 50 mg/kg cinnamaldehyde and 50 mg/kg carvacrol)were supplemented into the diets of 240 nursery pigs for 42 d,and data related to performance were ***,the influence of EO on intestinal health,appetite and gut microbiota and their correlations were *** supplementation increased(Pintestinal absorption area and the abundance of tight junction proteins,and decreased(Pintestinal permeability and local *** terms of intestinal development and the mucus barrier,EO promoted intestinal development and increased(Pintestinal health and ba

关键词： Nursery pig Essential oil intestinal health Appetite Microbiota

Effects of methionine supplementation in a reduced protein diet on growth performance, oxidative status, intestinal health, oocyst shedding, and methionine and folate metabolism in broilers under Eimeria challenge

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Journal of Animal Science and Biotechnology 2024年第5期15卷 1951-1979页

作者： Guanchen Liu Venkata Sesha Reddy Choppa Milan Kumar Sharma Hanseo Ko Janghan Choi Woo Kyun Kim Department of Poultry Science University of GeorgiaAthensGA 30602USA

Background This study investigated effects of different methionine(Met)supplementation levels in a reduced protein diet on growth performance,intestinal health,and different physiological parameters in broilers under Eimeria challenge.A total of 600 fourteen-day-old Cobb500 male broilers were challenged with ***,***,and ***,and randomly allocated in a 2×5 factorial *** received normal protein diets(20%crude protein,NCP)or reduced protein diets(17%crude protein,LCP),containing 2.8,4.4,6.0,7.6,and 9.2 g/kg of *** On 6 and 9 days post inoculation(DPI),increasing Met level linearly improved the growth performance(P<0.05).Total oocyst shedding linearly increased as Met level increased(P<0.05).Duodenal villus height(VH):crypt depth(CD)in the LCP groups were higher on 6 DPI(P<0.01)while lower on 9 DPI(P<0.05)compared to the NCP *** CD and duodenal VH:CD changed quadratically as Met level increased(P<0.05).On 6 DPI,liver glutathione(GSH)and glutathione disulfide(GSSG)linearly increased as Met level increased(P<0.05).On 9 DPI,GSSG quadratically increased,whereas GSH:GSSG quadratically decreased as Met levels increased(P<0.05).The expression of amino acid transporters linearly decreased as Met level increased(P<0.05).The expression of zonula occludens 2 and claudin-1 linearly increased on 6 DPI whereas decreased on 9 DPI as Met level increased(P<0.05).The expressions of cytokines were lower in the LCP groups than the NCP groups(P<0.05).Interaction effects were found for the expression of IL-10 and TNFαon 6 DPI(P<0.05),where it only changed quadratically in the NCP group as Met level *** expression of Met and folate metabolism genes were lower in the LCP groups than the NCP groups on 9 DPI(P<0.05).The expression of these genes linearly or quadratically decreased as Met level increased(P<0.05).Conclusion These results revealed the regulatory roles of Met in different physiological parameters including oxidative stat

关键词： Broiler Coccidiosis Eimeria intestinal health Methionine

Role of milk carbohydrates in intestinal health of nursery pigs: a review

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Journal of Animal Science and Biotechnology 2022年第3期13卷 628-641页

作者： Ki Beom Jang Sung Woo Kim Department of Animal Science North Carolina State UniversityRaleighNC 27695USA

intestinal health is essential for the resistance to enteric diseases and for nutrient digestion and absorption to support *** intestine of nursery pigs are immature and vulnerable to external challenges,which cause negative impacts on the structure and function of the *** nutritional interventions,the benefits of milk are significant for the intestinal health of *** coproducts have traditionally been used in starter feeds to improve the growth of nursery pigs,but their use is somewhat limited due to the high costs and potential risks of excessive lactose on the ***,understanding a proper feeding level of milk carbohydrates is an important start of the feeding *** nursery pigs,lactose is considered a highly digestible energy source compared with plant-based starch,whereas milk oligosaccharides are considered bioactive compounds modulating intestinal immunity and ***,milk carbohydrates,mainly composed of lactose and oligosaccharides,have essential roles in the intestinal development and functions of nursery *** proper feeding levels of lactose in starter feeds could be variable by weaning age,body weight,or genetic *** of lactose and milk oligosaccharides have been broadly studied in human health and animal ***,this review focuses on the mechanisms of lactose and milk oligosaccharides affecting intestinal maturation and functions through modulation of enterocyte proliferation,intestinal immunity,and intestinal microbiota of nursery pigs.

关键词： intestinal health Lactose Milk carbohydrates Milk oligosaccharides Nursery pig

Diet xylo-oligosaccharide supplementation improves growth performance, immune function, and intestinal health of broilers

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Animal Nutrition 2024年第2期17卷 165-176页

作者： Zhiyong Rao Yue Li Xiaopeng Yang Yongpeng Guo Wei Zhang Zhixiang Wang School of Animal Science and Technology Henan Agricultural University

The effects of xylo-oligosaccharides(XOS) on broiler growth performance, immune function, and intestinal health were investigated. A total of 540 one-d-old Arbor Acres Plus broilers were randomly divided into 5 groups with 6 replicates per group and 18 chickens per replicate. Broilers in the control(CON) group received a corn-soybean meal based basal diet, those in the antibiotics(ANT) group received the basal diet plus 500 mg/kg oxytetracycline, and those in XOS groups received the basal diet plus 150, 300, or 450 mg/kg XOS. Compared with CON, the body weight at 42 d and average daily gain from 1 to 42 d were significantly increased in the 150, 450 mg/kg XOS-added and ANT groups(P = 0.018),and the relative expression of claudin-1 and ZO-1 m RNA in the ileum was significantly higher in the 300and 450 mg/kg XOS-added groups(P intestinal health by enh

关键词： Xylo-oligosaccharide Growth performance intestinal health Immunity Broiler

Dietary Litsea cubeba essential oil supplementation improves growth performance and intestinal health of weaned piglets

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Animal Nutrition 2023年第2期13卷 9-18页

作者： Zhe Yang Fang Wang Yexin Yin Peng Huang Qian Jiang Zhimou Liu Yulong Yin Jiashun Chen Animal Nutritional Genome and Germplasm Innovation Research Center College of Animal Science and TechnologyHunan Agricultural UniversityChangshaHunan410128China CAS Key Laboratory of Agro Ecological Processes in Subtropical Region Institute of Subtropical AgricultureChangshaHunan410125China Hunan Nuoz Biological Technology Co. Ltd.YiyangHunan413056China

This paper was to determine the effects of dietary Litsea cubeba essential oil(LEO)supplementation on growth performance,immune function,antioxidant level,intestinal morphology and microbial composition in weaned *** hundred and ninety-two piglets(Duroc×[Large White×Landrace])with 6.85±0.22 kg mean body weight weaned at 21 d of age were randomly assigned to 4 treatment groups with 8 replicates and were fed with a basal diet(CON)or CON diet containing 100(LLEO),200(MLEO)and 400(HLEO)mg/kg *** results revealed that HLEO supplementation(Pintestinal health in weaned piglets.

关键词： Litsea cubeba Growth performance intestinal health Microbial composition Essential oil Weaned piglet