检索结果-南通市图书馆

Triple-functional bone adhesive with enhanced internal fixation,bacteriostasis and osteoinductive properties for open fracture repair

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2023年第7期25卷 273-290页

作者： Yusheng Yang Shenghui Su Shencai Liu Weilu Liu Qinfeng Yang Liangjie Tian Zilin Tan Lei Fan Bin Yu Jian Wang Yanjun Hu Division of Orthopaedics and Traumatology Department of OrthopaedicsNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong Province510515China Department of Orthopaedics Ningde Municipal HospitalNingde Normal UniversityNingdeFujian Province352100China Division of Orthopaedics Surgery Department of OrthopaedicsNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong Province510515China Department of General Surgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong Province510515China

At present,effective fixation and anti-infection implant materials represent the mainstay for the treatment of open ***,external fixation can cause nail tract infections and is ineffective for fixing small fracture ***,closed reduction and internal fixation during the early stage of injury can lead to potential bone infection,conducive to bone nonunion and delayed ***,we designed a bone adhesive with anti-infection,osteogenic and bone adhesion fixation properties to promote reduction and fixation of open fractures and subsequent soft tissue *** was prepared by the reaction of gelatin(Gel)and oxidized starch(OS)with vancomycin(VAN)-loaded mesoporous bioactive glass nanoparticles(MBGNs)covalently cross-linked with Schiff *** and adhesion experiments were conducted to validate the successful preparation of the Gel-OS/VAN@MBGNs(GOVM-gel)***,in vitro cell experiments demonstrated its good antibacterial effects with the ability to stimulate bone marrow mesenchymal stem cell(BMSCs)proliferation,upregulate the expression of alkaline phosphatase(ALP)and osteogenic proteins(RunX2 and OPN)and enhance the deposition of calcium ***,we established a rat skull fracture model and a subcutaneous infection *** histological analysis showed that bone adhesive enhanced osteogenesis,and in vivo experiments demonstrated that the number of inflammatory cells and bacteria was significantly ***,the adhesive could promote early reduction of fractures and antibacterial and osteogenic effects,providing the foothold for treatment of this patient population.

关键词： Open fracture Bone adhesive internal fixation Bacteriostasis Osteoinduction

Arthroplasty versus internal fixation for Displaced Intracapsular Femoral Neck Fracture in the Elderly： Systematic Review and Meta-analysis of Short- and Long-term Effectiveness

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2016年第21期129卷 2630-2638页

作者： Chen-Yi Ye An Liu Ming-Yuan Xu Nwofor Samuel Nonso Rong-Xin He Department of Orthopedic Surgery The Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou Zhejiang 310009 China Department of Plastic Surgery The First Affiliated Hospital School of Medicine Zhejiang University Hangzhou Zhejiang 310009 China

Background：There is conflicting evidence as to whether the femoral head should be preserved or replaced in elderly patients with displaced intracapsular femoral neck *** this article,we performed a systematic review and meta-analysis to compare the short-and long-term effectiveness of arthroplasty （AR） and internal fixation （IF）.Methods：PubMed,Embase,and the Cochrane Library were searched systematically up to January *** randomized controlled trials directly comparing the effectiveness of AR and IF for displaced intracapsular fracture were retrieved with no limitation on language or publication ***：In total,eight prospective randomized studies involving 2206 patients were *** results of our study showed that patients in the AR group reported significantly lower complication （risk ratio：0.56,95% confidence interval [CI] =0.38-0.80）,re-operation （risk ratio：0.17,95% CI =0.13-0.22）,revision rates （risk ratio：0.11,95% CI：0.08-0.16）,and better function compared with their IF counterparts,and they were less likely to suffer postoperative *** statistically significant differences for the rates of mortality,infection,and/or deep vein thrombosis between AR and IF were ***：Based on our analysis,we recommend that AR should be used as the primary treatment for displaced intracapsular femoral neck fractures in the ***,IF may be appropriate for those who are very frail.

关键词： Arthroplasty internal fixation Femoral Neck Fracture

Biomechanical Comparison of Two Kinds of internal fixation in a Type C Zone II Pelvic Fracture Model

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第17期128卷 2312-2317页

作者： Tao Wu Wei Chen Qi Zhang Zhan-Le Zheng Hong-Zhi Lyu Yun-Wei Cui Xiao-Dong Cheng Ying-Ze Zhang Yan-Jiang Yang Department of Orthopaedics Third Hospital Hebei Medical University Shijiazhuang Hebei 050051 China

Background： Unstable pelvic fractures are complex and serious injuries. Selection of a fixation method for these fractures remains a challenging problem for orthopedic surgeons. This study aimed to compare the stability of Tile C pelvic fractures fixed with two iliosacral （IS） screws and minimally invasive adjustable plate （MIAP） combined with one IS screw. Methods： This study was a biomechanical experiment. Six embalmed specimens of the adult pelvis were used. The soft tissue was removed from the specimens, and the spines from the fourth lumbar vertebra to the proximal one-third of both femurs were retained. The pubic symphysis, bilateral sacroiliac joints and ligaments, bilateral hip joints, bilateral sacrotuberous ligaments, and bilateral sacrospinous ligaments were intact. Tile C pelvic fractures were made on the specimens. The symphysis pubis was fixed with a plate, and the fracture on the posterior pelvic ring was fixed with two kinds of internal fixation in turn. The specimens were placed in a biomechanical machine at a standing neutral posture. A cyclic vertical load of up to 500 N was applied, and displacement was recorded. Shifts in the fracture gap were measured by a grating displacement sensor. Statistical analysis used： Paired-samples t-test. Results： Under the vertical load of 100, 200, 300, 400, and 500 N, the average displacement of the specimens fixed with MIAP combined with one IS screw was 0.46, 0.735, 1.377, 1.823, and 2.215 mm, respectively, which was significantly lower than that of specimens fixed with two IS screws under corresponding load （P 〈 0.05）. Under the vertical load of 500 N, the shift in the fracture gap of specimens fixed with MIAP combined with one IS screw was 0.261 ± 0.095 mm, and that of specimens fixed with two IS screws was 0.809 ± 0.170 mm. The difference was significant （P 〈 0.05）. Conclusion： The stability of Tile C pelvic fractures fixed with MIAP combined with one IS screw was better than that fixed with two IS screws.

关键词： Biomechanics internal fixation Pelvis Unstable

Management of intra-articular fracture of the fingers via mini external fixator combined with limited internal fixation

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2009年第21期122卷 2616-2619页

作者： LI Wen-jun TIAN Wen TIAN Guang-lei CHEN Shan-lin ZHANG Chang-qing XUE Yun-hao LI Zhong-zhe ZHU Yin Department of Hand Surgery Beijing Jishuitan Hospital Beijing 100035 China

Background Intra-articular fractures of the fingers are common problems to emergency physicians and hand surgeons Inappropriate management of these injuries may result in chronic pain, stiffness, deformity, or post traumatic arthritis. Ideal treatment necessitates the restoration of a stable and congruent joint that will allow early mobilization. The purpose of this study was to investigate the results of intra-articular fracture of the fingers by mini external fixator combined with limited internal fixation. Methods From May 2005 to May 2007, a total of 26 patients with intra-articular fracture of the fingers were treated by mini external fixator combined with limited internal fixation. Of the 26 cases, 11 involved in metacarpophalangeal joint, and 15 interphalangeal joint in proximal interphalangeal. Kirschner wire, mini wire and absorbable suture were used for limited internal fixation. All patients were followed up and patients were accomplished with total active motion （TAM） of fingers. Results All patients were reviewed by an independent observer. The mean follow up was 13 months （range 9 to 24 months）. Subjective, objective and radiographic results were evaluated. X-ray films revealed fracture union and the average radiographic union time was 7 weeks with a range of 5-12 weeks and the phalange shortening or rotation in 2 cases, joint incongruity （less than 1 mm） and joint space narrowing in 3 cases respectively. Phalangeal shortening or rotation was observed in 2 cases and joint incongruity or joint space narrowing was observed in 3 cases. An artificial implant was performed on one case for traumatic arthritis 1.5 years after surgery. Based on TAM the overall good-excellent rate of joint motion function was 80.8%. Conclusion Mini external fixator combined with limited internal fixation is a reliable and effective method for treatment of intra-articular fracture of the fingers.

关键词： external fixator intra-articular fracture internal fixation finger

Biomechanical analysis of the computer-assisted internal fixation of a femoral neck fracture

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2020年第3期7卷 448-455页

作者： Hui Lu Hongquan Shen Shuqing Zhou Weidong Ni Dianming Jiang Department of Orthopedic Surgery The First Affiliated Hospital of Chongqing Medical University1 Youyi RdChongqing400016PR China Department of Orthopedic Surgery Jiang Jin Central Hospital of Chongqing725 Jiangzhou AvenueJiang Jin DistrictChongqing402260PR China

The number and spatial configuration of the screws will affect the stability and prognosis of the *** our study,we assessed the biomechanical effects of the double-head cannulated compression screw(DhCCS)and ordinary cannulated compression screw(OCCS)for the treatment of femoral neck fractures by using computer finite element *** original digital imaging and communications in medicine(DICOM)data of a proximal femur were imported into Materialise’s interactive medical image control system(MIMICS)software for *** DhCCS and OCCS 3D-models were obtained by using the 3D scan *** the fracture model and internal fixation assembly model with an inverted triangle,two horizontal and vertical distribution were established in UG ***,the displacement and stress distribution were calculated in ANSYS *** displacement value of the femoral head in the DhCCS group was smaller than that in the OCCS group,and the displacement value in the two horizontal groups was smaller than that in the vertical *** stress distribution in the DhCCS group was concentrated on the screw rod at the fracture block and thread end,while only at the fracture block in the OCCS *** stress in the horizontal group was more dispersed on the screws than that in the vertical *** has reliable stability for the fixation of femoral neck fractures and applied in the clinical work and 2 horizontal fixation can be used when two screws are selected.

关键词： Biomechanics Cannulated compression screw Femoral neck fracture Finite element analysis internal fixation

Anterior internal fixation to treat vertical unstable pelvic fracture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华创伤杂志(英文版) 2002年第1期5卷 60-62页

作者：王世松张鹏程杜敦进杨泗华 Orthopedic Department People's Hospital of Ganyu County Jiangsu 222100 China.

With the Chinese development of industry, agriculture and communication, various traffic and work related accidents are increasing, leading to an increase in pelvic fractures. Among the different kinds of fractures, pelvic fracture is the third largest cause of death.1 The treatment of pelvic fractures is a “hot spot” and a difficult point in orthopedic surgery. Since 1998 we have treated 20 patients with vertical unstable pelvic fracture using anterior internal fixation. Satisfactory results have been obtained.

关键词： internal fixation cause of death

internal fixation of Gunshot Induced Fractures in Civilians: Anatomic and Functional Results of a Standard Protocol at an Urban Trauma Center

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Orthopedics 2016年第3期6卷 63-70页

作者： Anani Abalo Atsi Walla Gamal Ayouba Yaovi Yannick Dellanh Kosivi Fortey Assang Dossim Department of Orthopaedics Tokoin Teaching Hospital Lomé Togo

Introduction: Despite extensive experience with civilian gunshot fractures or wounds, no consensus exists on a standard protocol to manage these injuries. Many authors recommended immediate debridement, but the optimal timing of internal fixation and the use of antibiotic have not been determined. The purpose of this paper is to present and discuss our experience. Material and methods: In January 2007, a treatment protocol was put in place for the evaluation and management of fractured extremities resulting from civilian gunshot wounds. Sixty-three patients with 64 fractures had been managed by this protocol for gunshot fractures between January 2005 and January 2012. There were 56 male and seven female. Their mean age was 33.1 years (range: 17 - 61 years). Thirteen patients (20.6%) were able to provide a description of the weapon. Only 15 patients had entry and exit wounds. The mean follow-up period was 27 (range, 20 - 58) months. The main factors assessed were the surgical site infection, the fracture union and the functional status. Results: Out of the 63 patients, 14 patients developed a wound infection (five superficial and seven deep infections). Wound infection was significantly associated with associated injuries (p = 0.0388), fractures sites requiring fixation (p = 0.024), the fracture pattern (p = 0.0412), operative modalities (p = 0.0400). There were nine cases (14.1%) of fracture non-union. The mean time to union was 15 weeks (range: 5 - 32 weeks). Five patients developed chronics osteomyelitis. The average SMFA score for all of the patients was 23.8 (range: 0 - 56.3). The mean dysfunctional and bother indexes were 18.3 (range: 0 - 52.7) and 22.6 (range: 0 - 66.1), respectively. The SMFA total score and dysfunction index had a significant correlation based on presence or absence of associated injuries (p < 0.0001). But bother index did not show the same correlation (p = 0.452). The average length of hospital stay was 11.3 days (range: 3 - 64). Conclusion

关键词： Fracture Gunshot Fracture internal fixation Wound Infection Surgical Treatment

The Use of Calcaneal Anatomic Plate in Arthroscopically-assisted Open Reduction and internal fixation of Intra-articular Calcaneal Fractures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Huazhong University of Science and Technology(Medical Sciences) 2006年第3期26卷 319-321页

作者：王洪张青松段德宇严力军 Department of Orthopaedic Union Hospital Tongji Medical college of Huazhong University of Science and Technology WuHan 430022 China

To discuss and evaluate the method and effect of using calcaneal anatomic plate in treatment of intra-articular fractures of the calcaneus with assistant of arthroscope, 86 intra-articular fractures of the calcaneus in 78 patients were reduced by open reduction, and rigid fixation was made with calcaneal anatomic plate under assistant of arthroscope. The average follow-up duration was 18 months （range 12-30 months）. The effect of treatment was evaluated according to AOFAS and X-ray before and after operation. The results showed that 86 patients have obtained satisfactory reduction according to X-ray, and there was significant difference before and after operation （P〈0. 01）, the total excellent and fine rate was 91.86%. Treating intra-articular fractures of the calcaneus with calcaneal anatomic plate under arthroscope may provide more chance to achieve anatomical reconstruction, which can lead to satisfied recovery of function and few complication.

关键词： Fracture of Calcaneus Calcaneal Anatomic Plate Arthroscope internal fixation

internal fixation of comminuted pilon fracture fragments:Is dual plate fixation necessary?

在线全文

学校读者我要写书评

暂无评论

Internal Fixation of comminuted pilon fracture fragments:Is ...