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Elderly adults with COVID-19 admitted to intensive care unit:A narrative review

World Journal of Critical care Medicine 2021年第5期10卷 278-289页

作者： Aikaterini Gkoufa Eleni Maneta Georgios N Ntoumas Vasiliki E Georgakopoulou Athina Mantelou Stelios Kokkoris Christina Routsi First Department of Internal Medicine Laiko General HospitalNational and Kapodistrian University of AthensAthens 11527Greece First Department of intensive care School of MedicineNational and Kapodistrian University of AthensAthens 10676Greece

BACKGROUND In the context of the Coronavirus disease 2019(COVID-19)pandemic,it has been reported that elderly patients are particularly at risk of developing severe illness and exhibiting increased *** many studies on hospitalized elderly patients with COVID-19 have been published,limited information is available on the characteristics and clinical outcomes of those elderly patients admitted to intensive care unit(ICU).AIM To review the available evidence of the clinical data of elderly patients admitted to the ICU due to *** We searched for published articles available in English literature to identify those studies conducted in critically ill patients admitted to the ICU due to COVID-19,either exclusively designed for the elderly or for the whole ICU population with COVID-19,provided that analyses according to the patients’age had been *** Only one study exclusively focusing on critically ill elderly patients admitted to the ICU due to COVID-19 was *** additional studies involving 17011 ICU patients and providing information for elderly patients as a subset of the whole study population have also been included in the present review *** the whole patient population,included in these studies,8310 patients were older than 65 years of age and 2630 patients were older than 70 *** manifestations were similar for all patients;however,compared to younger ones,they suffered from more comorbidities and showed a varied,albeit high *** In summary,at present,although elderly patients constitute a considerable proportion of critically ill patients admitted to the ICU due to severe COVID-19,studies providing specific information are *** evidence so far suggests that advanced age and comorbidities are associated with worse clinical *** studies exclusively designed for this vulnerable group are needed.

关键词： SARS-CoV-2 COVID-19 Elderly Critically ill intensive care unit mortality Respiratory failure

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