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Recovery of a patient with severe COVID-19 by acupuncture and Chinese herbal medicine adjuvant to standard care

Journal of integrative Medicine 2021年第5期19卷 460-466页

作者： Xin Yin Shu-bin Cai Lan-ting Tao Lu-ming Chen Zhong-de Zhang Su-hong Xiao Arthur Yin Fan Xu Zou Department of Critical Care Medicine Second Clinical CollegeGuangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of General Medicine No.3 Division Second Clinical CollegeGuangzhou University of Chinese Medicine.Guangzhou 510120Guangdong ProvinceChina Department of Emergency Medicine Second Clinical CollegeGuangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Second Clinical College Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina SH Clinic for Acupuncture&Chinese Medicine Indianapolis.IN 46268USA TCM American Alumni Association(TCMAAA) IndianapolisIN 46268USA American TCM Association(ATCMA) ViennaVA 22182USA McLean Center for Complementary and Alternative Medicine PLCViennaVA 22182USA

There is currently no drug or therapy that can cure the coronavirus disease 2019(COVID-19), which is highly contagious and can be life-threatening in severe cases. Therefore, seeking potential effective therapies is an urgent task. An older female at the Leishenshan Hospital in Wuhan, China, with a severe case of COVID-19 with significant shortness of breath and decrease in peripheral oxygen saturation(SpO_(2)),was treated using manual acupuncture and Chinese herbal medicine granule formula Fuzheng Rescue Lung with Xuebijing Injection in addition to standard care. The patient’s breath rate, SpO_(2), heart rate,ratio of neutrophil/lymphocyte(NLR), ratio of monocyte/lymphocyte(MLR), C-reactive protein(CRP),and chest computed tomography were monitored. Acupuncture significantly improved the patient’s breathing function, increased SpO_(2), and decreased her heart rate. Chinese herbal medicine might make the effect of acupuncture more stable;the use of herbal medicine also seemed to accelerate the absorption of lung infection lesions when its dosage was increased. The combination of acupuncture and herbs decreased NLR from 14.14 to 5.83, MLR from 1.15 to 0.33 and CRP from 15.25 to 6.01 mg/L. These results indicate that acupuncture and Chinese herbal medicine, as adjuvants to standard care, might achieve better results in treating severe cases of COVID-19.

关键词： COVID-19 Severe case Case report Acupuncture Chinese herbal medicine integrative therapy

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Far infrared-emitting ceramics decrease Freund's adjuvant-induced inflammatory hyperalgesia in mice through cytokine modulation and activation of peripheral inhibitory neuroreceptors

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Journal of integrative Medicine 2018年第6期16卷 396-403页

作者： Ralph Fernando Rosas Aline Armiliato Emer Ana Paula Batisti Daniela Dero Ludtke Bruna Lenfers Turnes Franciane Bobinski Francisco Jose Cidral-Filho daniel fernandes martins Experimental Neuroscience Laboratory(LaNEx) University of Southern Santa CatarinaPalhoca 88137-272Santa CatarinaBrazil Postgraduate Program in Health Sciences University of Southern Santa CatarinaPalhoca 88137-272Santa CatarinaBrazil Laboratory of Bioenergetics and Oxidative Stress(LABOX) Federal University of Santa CatarinaFlorianopolis 88049-000Santa CatarinaBrazil

Objective： The present study aimed to evaluate the analgesic and anti-inflammatory effects of far infrared-emitting ceramics （cFIRs） in a model of persistent inflammatory hyperalgesia and to elucidate the possible mechanisms of these effects. Methods： Mice were injected with complete Freund＇s adjuvant （CFA） and treated with cFIRs via place- ment on a pad impregnated with cFIRs on the bottom of the housing unit for different periods of time. Mice underwent mechanical hyperalgesia and edema assessments, and tumor necrosis factor-α （TNF-α）, interleukin-1β （IL-1β） and IL-10 levels were measured. Twenty-four hours after CFA injection and 30 min before cFIR treatment, mice were pretreated with a nonselective adenosinergic antagonist, caffeine, the selective adenosine receptor A antagonist, 1,3-dipropyl-8-cyclopentylxanthine （DPCPX）, the selective cannabinoid receptor type 1 antagonist, AM281, the selective cannabinoid receptor type 2 antagonist, AM630, or the nonselective opioid receptor antagonist, naloxone, and mechanical hyperalge- sia was assessed. Results： cFIRs statistically （P 〈 0.05） decreased CFA-induced mechanical hyperalgesia （82.86 ±5.21）% in control group vs （56.67±9.54）% in cFIR group） and edema （（1699.0 ± 77.8） gm in control group vs （988.7±107.6） gm in cFIR group）, cFIRs statistically （P 〈 0.05） reduced TNF-α （0.478± 0.072） pg/mg of protein in control group vs （0.273 ±0.055） pg/mg of protein in cFIR group） and IL-113 （（95.81 ± 3.95） pg/mg of protein in control group vs （80.61 ±4.71）pg/mg of protein in cFIR group） levels and statistically （P〈 0.05） increased IL-10 （（18.32 ±0.78） pg/mg of protein in control group vs （25.89 ±1.23） pg/mg of protein in cFIR group） levels in post-CFA-injected paws. Peripheral pre-administration of inhibitory neuroreceptor antagonists （caffeine, DPCPX, AM281, AM630 and naloxone） prevented the analgesic effects of cF1Rs （P 〈 0.05）.Conclusion： These data provide additional support for the use of cFIRs in the treatment of painful in

关键词： Adenosine Cannabinoid Far infrared-emitting ceramics integrative therapy Inflammatory pain Opioid receptors

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A Cohort Study to Examine the Use of Chinese Herbal Medicine in Combination with Conventional Therapies for Patients with Hepatocellular Carcinoma in China

A Cohort Study to Examine the Use of Chinese Herbal Medicine...

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第十七届全国中西医结合肿瘤学术大会

作者： Lingling Sun Paul Fahey Xiaoshu Zhu Weng Ng Zhuo ping Chen Yiwen Qiu Hezheng Lai Jietao Lin Lizhu Lin integrative Cancer Centre Guangzhou University of Chinese Medicine First Affiliated Hospital School of Science and Health Western Sydney University National Institute of Complementary Medicine (NICM) Western Sydney University South West Sydney Local Health District

Background: Hepatocellular carcinoma(HCC) is one of the major malignancies associated with high mortality rates. Chinese herbal medicine(CHM) alone, or in combination with conventional therapies(CT) has been widely used for patients with HCC in China. This study was aimed to explore how integrative therapy(IT) with the combination of CHM and CT affects the survival of patients with intermediateadvanced HCC. Methods: A retrospective cohort study was performed at the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. Data of consecutive patients diagnosed with intermediate-advanced HCC and specific traditional Chinese medicine diagnostic pattern between January 2006 and December 2013 were retrieved from the electronic medical record system at the hospital. Patients were divided into three groups basedon the therapies used, i.e. IT, CHM alone and CT alone, and the survival times of these patients was compared. Results: A total of 328 patients were included in this study. Median follow up period was 26.4 months(95%CI: 22.7-38.9). Median overall survival was 11.0 months for IT, 8.6 months for CHM, and 9.4 months for CT groups(pintegrative approach with combination of CHM and CT might improve survival for patients with intermediate-advanced HCC, especially for patients with good PS and Child-Pugh class A. However, a randomized control trial is warranted for a conclusive statement.

关键词： Chinese herbal medicine hepatocellular carcinoma integrative therapy survival cohort study

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