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Effect of hydrogen intervention on refractory wounds after radiotherapy:A case report

World Journal of Clinical Cases 2022年第21期10卷 7545-7552页

作者： Peng-Xiang Zhao Rui-Liu Luo Zheng Dang You-Bin Wang Xu-Juan Zhang Zi-Yi Liu Xiao-Hu Wen Meng-Yu Liu Ming-Zi Zhang Yao Mawulikplimi Adzavon Xue-Mei Ma Faculty of Environment and Life Science Beijing International Science and TechnologyCooperation Base of Antivirus DrugBeijing University of TechnologyBeijing 100124China Department of Plastic Surgery Peking Union Medical College HospitalBeijing 100032China

BACKGROUND Patients with keloids who receive radiotherapy(RT)after surgery can develop refractory wounds that cannot be healed by the patient's own repair *** chronic wounds are uneven and complex due to persistent abscess and *** external intervention,they can easily result in local tissue necrosis or,in severe cases,large area tissue resection,amputation,and even *** SUMMARY This article describes the use of hydrogen to treat a 42-year-old female patient with a chronic wound on her left *** patient had a skin graft that involved implanting a dilator under the skin of her left shoulder,and then transferring excess skin from her shoulder onto scar tissue on her *** skin grafting was followed by two rounds of RT,after which the shoulder wound had difficulty *** six months,the patient was treated with 2 h of hydrogen inhalation(HI)therapy per day,in addition to application of sterile gauze on the wound and periodic *** also performed one deep,large,sharp debridement to enlarge the wound *** wound healed completely within 6 mo of beginning the HI *** After HI therapy,the patient showed superior progress in reepithelialization and wound repair,with eventual wound closure in 6 mo,in comparison with the previous failures of hyperbaric oxygen and recombinant bovine basic fibroblast growth factor *** work showed that HI therapy could be a new strategy for wound healing that is cleaner,more convenient,and less expensive than other therapies,as well as easily accessible for further application in clinical wound care.

关键词： Hydrogen inhalation therapy Wound healing Reepithelialization Refractory wounds Case report

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Clinical Efficacy Analysis of Tiotropium Bromide Combined with Budesonide and Formoterol inhalation in Treating COPD

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Journal of Clinical and Nursing Research 2024年第1期8卷 1-6页

作者： Hailing Lin Yanjie Lu Qingdao Shibei District People’s Hospital Qingdao 266011Shandong ProvinceChina

Objective:To analyze the clinical efficacy of tiotropium bromide(TB)combined with budesonide formoterol(BUD/FM)inhalation in treating chronic obstructive pulmonary disease(COPD).Methods:62 COPD patients admitted to the hospital between June 2020 and December 2022 were selected as samples for this *** patients were divided into a combination group and a conventional group using the random number table method,with 31 cases in each *** patients in the combination group were treated with TB combined with BUD/FM inhalation,whereas the patients in the conventional group were treated with BUD/FM inhalation *** treatment efficacy and changes in lung function indicators of both groups were ***:The total efficacy of treatment in the combined group was higher than that in the conventional group,and the difference was statistically significant(P0.05).After three months of treatment,all lung function indicators of the combined group were higher than those of the conventional group,and the difference was statistically significant(Pinhalation therapy increases the efficacy of treatment for patients with ***,it also improves lung function and leads to a better prognosis.

关键词： Tiotropium bromide Budesonide formoterol inhalation therapy Chronic obstructive pulmonary disease

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