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Research progress on the pathogenesis of aortic dissection

South China Journal of Cardiology 2022年第4期23卷 298-305页

作者： ZHAO Shuang LIU Jie WU Li SHA Yong-hong ZHU Ping School of Medicine Jishou UniversityJishou416000HunanChina Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences) Southern Medical UniversityGuangzhou510080GuangdongChina School of Medicine South China University of Technology Guangzhou510006GuangdongChina

Aortic dissection(AD) is a cardiovascular emergency with a high mortality rate, and the risk of death is estimated to increase by 1%-2% per hour. AD is complicated by variable clinical manifestations, and early detection and treatment can give more time for the treatment of *** is the most common cause of AD. In China, 65%-75% of patients with AD have poor blood pressure control. Patients with AD who are less than40 years of age are more likely to suffer from genetic diseases. Connective tissue disease(CTD) plays a dominant role in genetic diseases. Recently, inflammatory immunity, oxidative stress, obstructive sleep apnea-hypopnea syndrome(OSAHS), and other risk factors are being further studied. The new pathogenic factors should be explored to provide an accurate and effective prevention and treatment basis and new diagnostic methods and targets for drug therapy for AD.

关键词： aortic dissection hypertension connective tissue disease inflammatory immunity oxidative stress

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Advances in classification of aortic dissection

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岭南心血管病杂志:英文版 2023年第2期24卷 99-109页

作者：刘杰吴进林梁志超柯俊胡皓昀赵爽孙图成陈泽锐 School of Medicine South China University of Technology Guangzhou 510006GuangdongChina Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences) Southern Medical UniversityGuangzhou510080GuangdongChina School of Medicine Jishou UniversityJishou 416000HunanChina

Background Aortic dissection remains one of the most acute and critical diseases in cardiac surgery,with high mortality and disability *** the 1960s,DeBakeyfirst proposed the classification of aortic ***,various classifications of aortic dissection have been *** facilitate clinicians and medical staff involved in the treatment of aortic dissection to make better assessment of the condition of aortic dissection patients and to make reasonable clinical decisions,we reviewed several current mainstream classification *** hope that this paper inspires other researchers to propose a new,more suitable classification scheme for use in the clinical setting.

关键词： Aortic dissection Classification Connective tissue disease inflammatory immunity Oxidative stress

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