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Cancer statistics and trends in China:the potential of natural product application

Chinese Journal of Natural Medicines 2024年第8期22卷 673-675页

作者： LI Ting HUANG Muyang LU Jinjian State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao SAR 999078China MoE Frontiers Science Center for Precision Oncology University of MacaoMacao SAR 999078China Department of Pharmaceutical Sciences Faculty of Health SciencesUniversity of MacaoMacao SAR 999078China

Cancer presents a significant global challenge,impacting individuals,communities,and healthcare systems worldwide[1,2].Fundamentally,cancer involves the uncontrolled growth and proliferation of cells,driven by genetic and epigenetic alterations orchestrated by a complex array of molecular entities,including oncogenes,tumor suppressor genes,and various regulatory factors[3-5].This intricate interplay complicates early detection,often resulting in a significant mortality *** for nearly 30%of premature deaths globally,cancer is a major barrier to increasing human life expectancy[6,7].The urgent need for continued research,innovation,and collaborative efforts highlights the importance of combating this relentless disease.

关键词： Cancer incidence Mortality increasing trends Natural products

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A 14-year measurement of toxic elements in atmospheric particulates in Hong Kong from 1995 to 2008

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Frontiers of Environmental Science & Engineering 2014年第4期8卷 553-560页

作者： Wei NIE Tao WANG Aijun DING Xuehua ZHOU Wenxing WANG Environment Research Institute Shandong University Jinan 250100 China Department of Civil and Environmental Engineering The Hong Kong Polytechnic University Hong Kong China Institute for Climate and Global Change Research Nanjing University Nanjing 210009 China

Toxic elements in the atmosphere can enter and accumulate in the human body, seriously impacting human health. In this study, we analyzed a 14-year （1995-2008） measurement of three toxic elements （As, Cd and Cr） in PMlo in Hong Kong, China. The pollution of these toxic elements in Hong Kong was not serious. The trend analysis showed that As and Cr in PM10 increased at a statistically significant level （p〈0.05） during the 14-year period, while the Cd in PM10 did not change significantly. Typical seasonal variations were observed for all three toxic elements, largely in relation to the Asian monsoon. Hourly 10-day backward trajectories were computed and cate- gorised into four groups. The continental air masses showed much higher concentrations of the three toxic elements than the marine air masses. The abundances of As and Cd in the PM10 were much higher in the continental air masses than those in the marine air masses, while the abundances of Cr showed an opposite pattern. The trends of the three toxic elements in East China＇s air mass were consistent with those in the overall data set ofHong Kong. Examination of the toxic element data recorded at urban sites and a roadside site also indicated a large contribution of external air masses to particulate As and Cd in Hong Kong. These results suggest that the long-range transport from the mainland of China is the dominant contributor to particulate As and Cd, while both local and long-distance sources determine the particulate Cr in Hong Kong.

关键词： toxic elements increasing trends seasonal variations air masses long-distance sources

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