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Maculopapular Rash with Fever: Reporting of a Case with imported Measles and Diagnostic Difficulties in Non-Epidemic Times

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生物科学与医学(英文) 2023年第10期11卷 136-141页

作者： Ermira Muco Arta Karruli Arjan Harxhi Dhimiter Kraja Department of Infectious diseases University Hospital Tirana Albania

Background: Measles is a highly contagious infection caused by the measles virus with a worldwide distribution. Measles is one of the diseases that have been reported in our country since 1945. It is known that international travelers are an important source of infectious pathologies. Our goal is to document a case of imported Measles and the difficulty of diagnosing it, especially in non-epidemic times. Cases Presentation: We presently report a 20-year-old woman who was hospitalized at the Infectious Disease Service for fever and maculopapular rash. She had traveled outside of Albania. Measles ELISA IgM (blood) resulted positive while other serological examinations resulted negative. Our case was treated with antibiotics, multivitamins and intravenous fluids. She was subsequently discharged home in good clinical condition. Conclusions: Measles should be included in the differential diagnosis of patients with symptoms of fever and rash, in particular when they have traveled abroad. Patients who have received the Measles vaccine should not be excluded from clinical suspicion and further diagnostic tests for this disease as it can affect this group of patients as well.

关键词： Measles Travelers imported diseases Symptoms Serological Analysis

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imported Mansonella perstans infection in Spain

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Infectious diseases of Poverty 2020年第4期9卷 158-158页

作者： Sabino Puente Mar Lago Mercedes Subirats Ismael Sanz-Esteban Marta Arsuaga Belén Vicente Montserrat Alonso-Sardon Moncef Belhassen-Garcia Antonio Muro Unidad de Medicina Tropical Servicio de Medicina InternaHospital La Paz-Carlos IIIMadridSpain Microbiología Hospital La Paz-Carlos IIIMadridSpain Facultad de Fisioterapia Universidad Europea de MadridMadridSpain Laboratorio de Inmunología Parasitaria y Molecular CIETUSIBSALFacultad de FarmaciaUniversidad de Salamanca37007SalamancaSpain Área de Medicina Preventiva y Salud Pública IBSALCIETUSUniversidad de SalamancaSalamancaSpain Servicio de Medicina Interna Sección de Enfermedades InfecciosasCAUSAIBSALCIETUSUniversidad de SalamancaPaseo San Vicente 58-18237007SalamancaSpain

Background Mansonella perstans infection can be considered one of the most neglected tropical infectious diseases.Very few studies have reported on the clinical picture caused by infection with this nematode.Therefore,our study was aimed to describe the clinical patterns and treatment of imported M.perstans infection by migrants from Africa.Methods The present study evaluated a large cohort of migrants who have been diagnosed,examined and treated for imported M.perstans infection at a Spanish reference center(Hospital Carlos III Tropical Medicine Unit,Madrid,Spain)over a 19-year period.Most patients voluntarily attend the emergency unit or are referred from primary care or general hospitals in Madrid.Chi-square test was used to compare the association between categorical variables.The continuous variables were compared by Student’s t-test or the Mann–Whitney test.The corresponding regression models were used for multivariate analysis.Results Five hundred three cases of migrants from tropical and subtropical areas with M.perstans infection were identified.Two hundred sixty-four patients were female(52.5%).The mean age(±SD)was 44.6±18.2 years(range:16–93 years).The mean time(±SD)between the arrival in Spain and the first consultation was 8.6±18.0 months.The major origin of the patients was Equatorial Guinea(97.6%).Regarding the clinical picture,257 patients were asymptomatic(54.7%)and 228 were symptomatic(45.3%);190 patients had pruritus(37.8%),50(9.9%)had arthralgia,18 patients had Calabar-like swelling(3.6%),and 15(3%)had abdominal pain.Four hundred forty-two(87.9%)migrants had hyper-IgE,and 340(67.6%)had eosinophilia.One hundred ninety-five patients had coinfections with other filarial nematodes(38.8%),and 308 migrants had only M.perstans infection(61.2%).Four hundred thirty-seven cases(86.9%)had been treated with anti-filarial drugs;292 cases were treated with one anti-filarial drug,and 145 cases were treated with combined anti-filarial therapy.Additionally,20(4%)cases received steroids and 38(7.6%)cases receiv

关键词： Mansonellosis Mansonella perstans Clinical study Immigrant imported diseases Spain

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