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Management of retroperitoneal sarcoma involving the iliac artery:Single-center surgical experience

World Journal of Clinical Cases 2022年第3期10卷 811-819页

作者： Wen-Xiang Li Han-Xing Tong Chen-Tao Lv Hua Yang Gang Zhao Wei-Qi Lu Yong Zhang Department of General Surgery Shanghai Public Health Clinical CenterFudan UniversityShanghai 200083China Department of General Surgery Zhongshan HospitalFudan UniversityShanghai 200032China

BACKGROUND Management of retroperitoneal sarcoma(RPS)involving the iliac artery is challenging and requires the concerted efforts of multidisciplinary team(MDT)members during surgical *** To summarize the clinicopathologic features of RPS involving the iliac artery and our retroperitoneal soft tissue tumor MDT surgical *** In this retrospective study,15 patients with RPS involving the iliac artery who underwent surgery at our retroperitoneal soft tissue tumor center from July 2004 to June 2020 were *** analyses were performed by Student’s ttest with SPSS *** Complete tumor resection(R0/R1)and iliac artery reconstruction were achieved in all 15 *** the operations were successful,with no serious complications or perioperative *** with bilateral iliac artery reconstruction required a higher intraoperative blood transfusion volume than resection with unilateral iliac artery *** cases were more likely to bleed and required a higher blood transfusion volume than primary *** of January 2021,11 patients were alive,and 4 had *** recurrence occurred in two patients,one of whom developed liver *** Resection of RPS involving iliac vessels is feasible and effective when performed by MDT *** artery oncovascular resection and reconstruction are key to a successful *** blood preparation is important for successful completion of surgery.

关键词： Retroperitoneal sarcoma Vascular reconstruction Multidisciplinary team iliac artery Blood transfusion

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Isolated blunt iliac artery injury successfully treated with endovascular stent

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Chinese Journal of Traumatology 2022年第4期25卷 242-244页

作者： Ee Peng Lee Tan Jih Huei Tan Chor Lip Henry Bakin Salinawati Mohamad Yuzaidi Imran Alwi Rizal Department of General Surgery Hospital Sultanah AminahJohor BahruMalaysia

Common or external iliac artery injury due to blunt trauma is unusual without an associated pelvic *** we report on a 62 years old man that sustained left external iliac artery thrombosis due to blunt trauma following fall from *** was no immediate circulatory *** CT of abdomen revealed an associated left lower abdominal wall traumatic *** iliac artery was intervened with an endovascular stent to restore luminal flow and the hernia was repaired *** entire clinical course and management dilemma are described in this article.

关键词： iliac artery Stents Blunt injuries

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A Polymer Coated Cicaprost-Eluting Stent Increases Neointima Formation and Impairs Vessel Function in the Rabbit iliac artery

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Pharmacology & Pharmacy 2016年第6期7卷 226-235页

作者： Christopher McCormick Robert L. Jones Roger M. Wadsworth Alexander B. Mullen Simon Kennedy Biomedical Engineering Department University of Strathclyde Glasgow UK Strathclyde Institute of Pharmacy and Biomedical Sciences University of Strathclyde Glasgow UK Institute of Cardiovascular and Medical Sciences University of Glasgow Glasgow UK

Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer. In this study we implanted stents coated with cicaprost, a prostacyclin analogue with a long plasma half-life and antiproliferative effects on vascular smooth muscle cells, into the iliac arteries of rabbits. At 28-day follow-up we compared neointima formation within the stented vessels and vascular function in adjacent vessels, to assess if cicaprost could reduce restenosis without impairing vessel function. Arteries implanted with cicaprost eluting stents had significantly more neointima compared to bare metal stents. In adjacent segments of artery, endothelium-dependent relaxation was impaired by the cicaprost-eluting stent but vasodilation to an endothelium-independent vasodilator was maintained. We conclude that the presence of the polymer and sub-optimal release of cicaprost from the stent may be responsible for the increased neointma and impaired functional recovery of the endothelium observed. Further experiments should be aimed at optimising release of cicaprost and exploring different stent polymer coatings.

关键词： Cicaprost Neointima iliac artery Endothelium Drug-Eluting Stent

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Subsequent pregnancy outcomes and fertility rates in the case series that underwent bilateral hypogastric artery ligation(BHGAL)due to severe postpartum hemorrhage

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Asian pacific Journal of Reproduction 2024年第1期13卷 28-33页

作者： OKUTUCU Gulcan EVSEN Mehmet S PEKER Nurullah YAMAN TUNC Senem ICEN Mehmet S Department of Obstetrics and Gynecology Division of PerinatologyTurkish Ministry of Health Ankara City HospitalAnkaraTurkey Department of Obstetrics and Gynecology Dicle UniversitySchool of MedicineDiyarbakirTurkey

Objective:To evaluate the effect of bilateral hypogastric artery ligation(BHGAL)on women's pregnancy outcomes and fertility rates in cases with severe postpartum ***:Patients hospitalized in a tertiary care center between 2007 and 2018 were included in the *** records of cases were obtained from the hospital database,*** demographic data,morbidities or complications associated with BHGAL surgery,any additional haemostatic interventional or surgical procedures,preoperative admission and lowest postoperative haematocrit-hemoglobin values,blood products given,type of anaesthesia,intensive care unit(ICU)and length of hospital stay were *** cases without surgical sterilization,future fertility and subsequent pregnancy outcomes were assessed for at least two years after *** was obtained through face-to-face or telephone interviews with patients whose long-term fertility and subsequent pregnancy outcomes were ***:Sixty-eight patients with BHGAL surgery history were included in the study.26 Of 37 cases(70%)that did not undergo surgical sterilization had a desire for pregnancy after the *** of these cases(23%)were diagnosed with secondary *** fertility rate of these cases was 77%,and subsequent pregnancy was detected in 20 women.A total of 25 pregnancies,including first and second pregnancies,developed,and 15 of these pregnancies resulted in term delivery,six preterm births,one stillbirth,and three ***:The postoperative pregnancy rate was found to be higher than the rate of women with infertility problems,and this surgery does not seem to adversely affect pregnancy *** is a tertiary center experience and cohort studies with large patient series are needed.

关键词： Fertility iliac artery Ligations Postpartum hemorrhage Pregnancy outcomes

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Evidence of apoptotic smooth muscle cells in proliferative intima of injured arteries

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Chinese Medical Journal 2000年第1期113卷 10-13页

作者：黄峻尹航冷静姚玉宇姚蓉芬彭韬李晶阁 Department of Cardiology Hosp. of Nanjing Medical University Nanjing 210029 China Department of Pathology Nanjing Medical University Nanjing 210029 China

OBJECTIVE: To investigate the occurrence and extent of apoptosis in the course of restenosis. METHODS: The experimental models of vessel narrowness and intima thickness were established in minipigs' iliac arteries by balloon injury and specimens were retrieved on the 1st, 3rd, 6th, 12th and 30th days for dynamic observation. Apoptotic smooth muscle cells (SMCs) were detected by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL). RESULTS: Apoptotic SMCs occurred only in the thickened intima 12 days after injury accompanied with the proliferative SMCs, the percentage of apoptosis was 1.94% +/- 0.42% on the 12th day and 1.36% +/- 0.31% on the 30th day respectively. The low frequency of apoptosis compared with the proliferative SMCs was a feature in the restenotic pathology. CONCLUSIONS: Apoptosis participates in the pathogenetic process of intimal thickening and its level was low compared with proliferation. The findings suggest that attempts to modulate apoptosis after vessel injury constitute a theoretical approach to the prevention of restenosis.

关键词： Apoptosis Animals Arterial Occlusive Diseases Cell Division iliac artery Muscle, Smooth, Vascular Research Support, Non-U.S. Gov't Swine Swine, Miniature

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