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Hematology and blood serum chemistry reference intervals for children in iganga district of Uganda

Health 2013年第8期5卷 1261-1267页

作者： Fred Kironde Musa Sekikubo Halima Naiwumbwe Fatuma Namusoke William Buwembo Steven Kiwuwa Brenda Oketch Ramadhani Noor Roma Chilengi Edison Mworozi Mark Kaddumukasa African Malaria Network Trust Dar-es Salaam Tanzania Centre for Infectious Disease Research in Zambia (CIDRZ) Lusaka Zambia Makerere University College of Health Sciences Kampala Uganda

In this study, normal ranges for hematology and serum biochemistry in children aged 1 to 5 years inUgandawere determined. By a cross-sectional study, 1168 children from iganga, a prospective site for clinical trials in Uganda, were screened. From 1168 households, 460 children were selected for enrollment, while 600 (58%) were excluded because of either a history of fever in the previous 24 hours, presence of asexual malaria parasites in the peripheral blood or presence of fever. Accordingly, 460 children (39.4%) of median age = 3 years were enrolled in the baseline study. While the lower limits of hemoglobin, hematocrit levels, mean corpuscular volume and platelet counts for the Ugandan children were found to be less than conventional reference values of Caucasisan children, the white blood cell count reference values were higher than the international intervals. On the other hand, the upper limits of the reference intervals for serum transaminases, bilirubin, creatinine, urea, total protein and albumin in sera of the Ugandan children were higher than the corresponding values for a Caucasian pediatric population. This study showed that, if hematology test results of the Ugandan children were assessed against “imported” international reference values, up to 44.6% of the study participants would have been excluded from clinical trials or would have been reported as adverse events in such trials. The present study was not only the first report of serum biochemistry reference ranges for children aged one to five years in Uganda but also one of very few such studies in Africa.

关键词： Normal Intervals Reference Uganda Children Hematology Serum Biochemistry iganga

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Practice and knowledge of the dangers of self-medication among pregnant mothers attending antenatal care in iganga District (Uganda)

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Nursing Communications 2022年第1期6卷 68-76页

作者： Sarah Namususwa Rebecca Nakaziba Department of Pharmacology and Therapeutics Faculty of MedicineLira UniversityLira P.O Box 1035Uganda Department of Nursing and Midwifery Faculty of Health SciencesLira UniversityLira P.O Box 1035Uganda

Background:Self-medication is a common practice among pregnant mothers in many developing countries Uganda *** its adverse effects to the pregnant mother and the developing fetus,limited efforts are in place to reduce the *** study was conducted to assess the practices and knowledge of the dangers of self-medication among pregnant mothers attending antenatal care in iganga district,*** s:A cross sectional approach was employed using convenient sampling technique among 181 pregnant mothers at the antenatal *** interviewer administered questionnaire was used to collect data that was analyzed descriptively using SPSS ***:Out of the 181 respondents,119(65.75%)self-medicated during their current pregnancy obtaining drugs from pharmacies 42(23.20%).Majority of the mothers 129(71.27%)had good knowledge concerning the dangers of self-medication with 66.85%reporting that it was a bad *** the dangers of self-medication,23.76%reported fetal death while 24.86%stated *** was a significant association between self-medication practice and occupation(P-value=0.04;OR=1.21 at 95%CI).Conclusion:Self-medication remains a common practice among pregnant mothers in iganga district despite the fact that a large proportion of them have good knowledge regarding the dangers of ***,further investigations into the associated factors and strict measures to combat the risks of self-medication during pregnancy should be embarked on.

关键词： self-medication dangers pregnant mothers iganga

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