检索结果-南通市图书馆

Association between the Lung Immune Prognostic Index and mortality in patients with idiopathic inflammatory myopathy-associated interstitial lung disease

引用

Asian Pacific Journal of Tropical Medicine 2023年第11期16卷 515-521页

作者： Dan Luo Zhihao Zhao Caizheng Li Wenjun Zhu Wei Zhou Lirong He Huifeng Yan Qiaoli Su General Practice Ward/International Medical Center Ward General Practice Medical CenterWest China HospitalSichuan UniversityChengdu 610041China Department of Biomedical Engineering the Chinese University of Hong KongSha TinHong Kong SAR 999077China Department of Respiratory Medicine the Second Affiliated Hospital of Nanchang UniversityNo.1 Minde RoadNanchang 330006China Center for Prevention and Treatment of Cardiovascular Diseases the Second Affiliated Hospital of Nanchang UniversityNanchang 330006China Department of Medical Imaging Center the Second Affiliated Hospital of Nanchang UniversityNo.1 Minde RoadNanchang 330006China

Objective:To explore the association between the Lung Immune Prognostic Index(LIPI)and 1-year all-cause mortality in patients with idiopathic inflammatory myopathy related interstitial lung disease(IIM-ILD).Methods:Patients who were diagnosed with IIM-ILD at West China Hospital,Sichuan University from January 2008 to December 2021 were retrospectively included and categorized into three groups based on *** and multivariable Cox proportional hazards models were conducted to explore potential association between the LIPI and patients'***:A total of 1116 patients were screened,and 830 were included in this *** multivariable Cox analysis showed that,compared with patients with poor LIPI,the hazard ratio(HR)for all-cause 1-year mortality was 0.22(95%CI 0.05-0.93,P=0.04)for patients in the good LIPI group(LDH<250 IU/L and dNLR<3).After excluding patients lost to follow-up within one year,a similar result was found for LIPI(HR 0.20,95%CI 0.05-0.86;P=0.03).Conclusions:Good LIPI was independently associated with decreased risk of all-cause 1-year mortality in patients with *** easy-to-obtain index might be served as a potential marker for assessing the prognosis of IIM-ILD.

关键词： idiopathic inflammatory myopathy Interstitial lung disease Lung Immune Prognostic index All-cause mortality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phenotypical statin-associated immune-mediated necrotizing myositis with histological features of inclusion body myositis

引用

Rheumatology & Autoimmunity 2023年第1期3卷 50-55页

作者： Nicole Daver Sara Tonini Overlook Medical Center Institute for Rheumatic and Autoimmune DiseasesAtlantic Health SystemsSummitNew JerseyUSA

Introduction:Statin-associated immune-mediated necrotizing myositis(IMNM)is a rare but distinct idiopathic inflammatory myopathy(IIM)that requires early recognition and intervention to prevent irreversible muscle *** is typically characterized by active statin use,elevated creatinine kinase(CK)levels,proximal muscle weakness,and at times,a positive 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase(HMGCR)*** includes immediate discontinuation of the statin and may include corticosteroids,intravenous immunoglobulin(IVIG),and/or immunosuppressive *** body myositis(IBM),another distinct IIM,also presents with elevated CK levels but with insidious onset of distal upper and proximal lower extremity weakness and is typically refractory to *** Description:A 64-year-old female patient presented with proximal muscle weakness,elevated CK levels,and a positive HMGCR antibody in the setting of statin use with muscle pathology suggestive of both statinassociated IMNM and *** responded to subcutaneous methotrexate and a slow prednisone taper over several months,however,will require close monitoring for symptoms associated with either ***:In conclusion,we report a case of muscle weakness with muscle pathology demonstrating both statin-associated IMNM and *** case highlights the importance of understanding the clinical and pathological features of statin-associated IMNM and IBM.

关键词： 3-hydroxy-3-methyl-glutaryl-coenzympe A reductase antibody idiopathic inflammatory myopathy immune-mediated necrotizing myositis inclusion body myositis statin-associated myositis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：