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Analysis of two cases of patent ductus arteriosus ligation in preterm identical twins and literature review

Journal of Hainan Medical University 2020年第17期26卷 57-60页

作者： Xiang Cao Xiao-Ding Chen Ling Yang Ren-Wei Chen Yan Li Ze-Lai Mo Wei Xiang Neonatology Department Hainan Women and Children’s Medical CenterChildren’s Hospital of Hainan Medical UniversityHaikouHainan 570206China Cardio-Thoracic Surgery Department Hainan Women and Children’s Medical CenterChildren’s Hospital of Hainan Medical UniversityHaikouHainan 570206China Anesthesiology Department Hainan Women and Children’s Medical CenterChildren’s Hospital of Hainan Medical UniversityHaikouHainan 570206China Ultrasound Imaging Department Hainan Women and Children’s Medical CenterChildren’s Hospital of Hainan Medical UniversityHaikouHainan 570206China Key Laboratory of Tropical Translational Medicine Ministry of EducationHainan Medical UniversityHaikouHainan 571199China

Objective:To investigate the timing and effect of surgical ligation in the treatment of patent ductus arteriosus(PDA)in preterm identical ***:Retrospective analysis was made on the treatment of 2 cases of preterm twins with hemodynamic significant PDA(hsPDA)with corresponding clinical manifestation in our neonatology department,and literatures of PDA ligation for preterm twins were ***:These 2 cases were naturally conceived monochorionic diamniotic twins,with gestational age 30+2 weeks,birth weight was 1510g and 780g for larger twin and smaller twin,with birth weight discordance 48.3%.They both developed hsPDA with corresponding clinical manifestation,series Echocardiography showed evidence of left to right shunting and cardiac insufficiency which were left atrial and ventricular enlargement,large PDA(2.8~3.5mm),failed two courses of ibuprofen,N-terminal pro-brain natriuretic peptide level increased significantly,finally received surgical ligation with significant clinical improvement and no related complications.12 cases were found from literature search,including our 2 cases,of these,2 died,9 were cured and 1 improved *** 6 cases whose detailed information were available,4 infants were identical twins,2 ***:Preterm identical twins have the same genetic basis,the possibility of PDA ligation for both the larger twin and smaller twin should be alerted if the gestaional age is small and birth weight discordance is above 30%.If preterm twins have hsPDA who may fail ibuprofen treatment,surgical ligation should be considered early,and it is safe and effective.

关键词： identical twins Preterm infant Patent ductus arteriosus ligation

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公猪肾脏胎儿的一例报告

引用

华中农业大学学报 1985年第1期 25-29页

作者：秦春圃华中农学院牧医系

在公猪肾脏内发现一个雄性胎儿。躯干长8.2厘米,相当于50至60天的正常猪胎儿。胎儿面部宽阔、平直,没有咀筒,口宽大,脑秃而圆,颈部细缩,后躯比前躯高,四脚均有五指(趾),尾很长。胎儿胎膜与公猪肾皮质直接接触,建立简单的胎盘联系,进行... 详细信息

在公猪肾脏内发现一个雄性胎儿。躯干长8.2厘米,相当于50至60天的正常猪胎儿。胎儿面部宽阔、平直,没有咀筒,口宽大,脑秃而圆,颈部细缩,后躯比前躯高,四脚均有五指(趾),尾很长。胎儿胎膜与公猪肾皮质直接接触,建立简单的胎盘联系,进行物质交换。其内部器官均与同龄正常猪胎儿相类似,经鉴定,确定为孪生寄生体。这种罕见的寄生现象,说明家畜胚胎在发育过程中与环境因素的相互作用是极为复杂的,它对家畜遗传繁育和未来的胚胎操纵提供了新的研究线索。

关键词： Twin parasite identical twins Embryo Boar

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