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通讯世界 2002年第11期8卷 103-103页

Optimising soft tissue in-growth in vivo in additive layer manufactured osseointegrated transcutaneous implants

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Biomaterials Translational 2022年第4期3卷 243-249页

作者： Elena Giusto Gordon Blunn Roberta Ferro de Godoy Chaozong Liu Catherine Pendegrass Institute of Orthopaedic&Musculoskeletal Science University College LondonRoyal National Orthopaedic HospitalStanmoreUK Barts and the London School of Medicine and Dentistry Queen Mary University LondonLondonUK School of Pharmacy and Biomedical Sciences University of PortsmouthPortsmouthUK Writtle University College WrittleUK

Osseointegrated transcutaneous implants could provide an alternative and improved means of attaching artificial limbs for amputees,however epithelial down growth,inflammation,and infections are common failure modalities associated with their *** overcome these problems,a tight seal associated with the epidermal and dermal adhesion to the implant is *** could be achieved with specific biomaterials(that mimic the surrounding tissue),or a tissue-specific design to enhance the proliferation and attachment of dermal fibroblasts and *** intraosseous transcutaneous amputation prosthesis is a new device with a pylon and a flange,which is specifically designed for optimising soft tissue *** the flange has been fabricated using traditional machining techniques,however,the advent of additive layer manufacturing(ALM)has enabled 3-dimensional porous flanges with specific pore sizes to be used to optimise soft tissue integration and reduce failure of osseointegrated transcutaneous *** study aimed to investigate the effect of ALM-manufactured porous flanges on soft tissue ingrowth and attachment in an in vivo ovine model that replicates an osseointegrated percutaneous *** 12 and 24 weeks,epithelial downgrowth,dermal attachment and revascularisation into ALM-manufactured flanges with three different pore sizes were compared with machined controls where the pores were made using conventional *** pore sizes of the ALM flanges were 700,1000 and 1250μ*** hypothesised that ALM porous flanges would reduce downgrowth,improve soft tissue integration and revascularisation compared with machined *** results supported our hypothesis with significantly greater soft tissue integration and revascularisation in ALM porous flanges compared with machined controls.

关键词： in-vivo model itap orthopaedic implants osseointegrated transcutaneous implants

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电子产品世界 2003年第4A期10卷 65-65页

情报的企业化（一）：英国情报技术咨询委员会报告简介

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国外情报科学 1992年第2期10卷 27-31页

作者：杉本由利彭守正

英国在国际上的工业竞争能力虽有所碱弱,但在情报信息产皿方面却同美国一样,属于发达国家,具有独特的情报研究传统。曾出版几种早有定评的摘录,检索杂志,不断致力发展新型传输媒介手段. 美国首相早在I 9B9年就任命了情报技术方面的幸在... 详细信息

英国在国际上的工业竞争能力虽有所碱弱,但在情报信息产皿方面却同美国一样,属于发达国家,具有独特的情报研究传统。曾出版几种早有定评的摘录,检索杂志,不断致力发展新型传输媒介手段. 美国首相早在I 9B9年就任命了情报技术方面的幸在大臣,1981年又设立了情报技术咨询委员会(/TAP)-井把1 9B2年窀为靖报技术年.而日本开始使用斯传输煤介一谪却是在1982年柬－198年初,198 3年才提出高度情报时.把由此可见英国跛府箍如何重视发屉恃报拄术,并采取相应措赭以适应对代潮流. 这里编译的是上进情报技术眷询委员台1983年9月提出曲报告.该报告是建议英国政府应如何参与情报奇面服务的产物,是属于倚报政策的范畴.超对于政府申设有负舞情报的部九,没有全面情报政策的日奉来说很值得蓄考.对于我国也有参考价值。[编者按]

关键词：情报机构企业化英国 itap