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Health 2022年第5期14卷 477-506页

作者： Stefano Tugnoli Savino Spadaro Francesca Dalla Corte Giorgia Valpiani Carlo Alberto Volta Stefano Caracciolo Neurological Psychiatric and Psychological Sciences Section Department of Neuroscience and Rehabilitation Faculty of Medicine Pharmacy and Prevention University of Ferrara Ferrara Italy Anesthesia and Intensive Care Unit Section Department of Neuroscience and Rehabilitation Faculty of Medicine Pharmacy and Prevention University of Ferrara Ferrara Italy Research and Innovation Office University Hospital S. Anna Ferrara Italy

We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (icu) survivors 12 months after icu discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify icu survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 icu survivors who stayed in the icu for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in icu survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in icu survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in icu survivors.

关键词： icu survivors Psychological Distress Health-Related Quality of Life SF-36 Health Survey Scaled General Health Questionnaire (GHQ-28)

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