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Improving quality of life in self-reported gastrointestinal disorders: An open trial of a food elimination diet guided by the ImmunoBloodprint food sensitivity test

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Open Journal of Internal Medicine 2013年第3期3卷 106-113页

作者： Judi M. Woolger Johanna Lopez Angelica B. Melillo Eduard Tiozzo Yaima Alonso Soyona Rafatjah Amine Sarabia Susanna M. Leonard Evan G. Long Michael Schoor Jared Tannenbaum Janet Konefal John E. Lewis 3Department of Psychiatry & Behavioral Sciences University of Miami Miller School of Medicine Miami USA Department of Dietetics and Nutrition Florida International University Miami USA Department of Medicine University of Miami Miller School of Medicine Miami USA Department of Psychiatry & Behavioral Sciences University of Miami Miller School of Medicine Miami USA

Purpose: Irritable bowel syndrome (ibs) and gastrointestinal (GI) disorders are genuine health problems that have serious consequences on a patient’s quality of life (QoL). ibs is a functional disorder characterized by chronically recurring symptoms, including abdominal pain or discomfort, altered stool frequency and consistency, and abdominal bloating in the absence of structural or biochemical abnormalities. Studies have indicated that symptoms and disability related to ibs and GI disorders correlate with QoL measures. Additionally, those who respond to therapy have an improvement in QoL. Therefore, we explored an open trial of a food elimination diet guided by the ImmunoBloodprint food sensitivity test and its effect on QoL in patients self-reporting an unresolved GI disorder. Methods: Eighty-four subjects aged 18 and above participated in the study. Subjects eliminated all IgG-mediated reactive foods from their diet for 90 days. QoL was assessed with the Irritable Bowel Syndrome-36 (ibs-36) and the Medical Outcomes Study Short Form-36 (SF-36) at baseline and 30-, 60-, and 90-day follow-up. The data were analyzed with linear mixed models. Results: Subjects had statistically significant improvements in all indicators of QoL according to the ibs-36 and SF-36 from baseline to 90- day follow-up. Conclusions: Subjects with unresolved self-reported GI disorders were able to improve all indicators of QoL in response to eliminating IgG- reactive foods from the diet. Given the inconvenience of keeping track of foods and symptoms to eliminate intolerant foods, a food sensitivity test combined with an elimination diet may be an effective method for improving subjective markers of QoL and health.

关键词： GI Disorders Food Sensitivity Testing Elimination Diet Food Intolerance ibs-36 SF-36

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