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Rapid progression of heart failure secondary to radioactive iodine treatment of hyperthyroidism:A case report

World Journal of Clinical Cases 2023年第22期11卷 5316-5321页

作者： Zi-Han Li Lu-Jia Ni Yuan-Qiao Liu Dao-Yuan Si Department of Cardiology China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Jilin Provincial Engineering Laboratory for Endothelial Function China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Ultrasound China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

BACKGROUND The deterioration of thyroid health is involved in the progression of heart failure(HF).This is usually a lengthy process,so there are almost no reports on its rapid *** we report a case of a young male who rapidly developed hypothyroid cardiomyopathy secondary to radioactive iodine treatment,suggesting that severe HF might occur even after a short period of *** SUMMARY A 26-year-old man was referred to our hospital for HF presenting with dyspnea on exertion and chest discomfort lasting for 1 *** received radioactive iodine treatment for hyperthyroidism 1 year ago and had an almost normal echocardiogram 6 mo *** echocardiogram and cardiac magnetic resonance(CMR)revealed left ventricle(LV)global hypokinesia and severely depressed systolic *** addition,late gadolinium enhancement indicated no obvious changes in the *** function tests showed decreased serum levels of thyroid hormone(TH)and elevated thyroid-stimulating *** on an exclusionary examination,the patient was diagnosed with hypothyroid cardiomyopathy and was started on replacement *** HF symptoms were completely relieved during the six-month follow-up,and echocardiogram and CMR revealed recovered LV size and ejection *** This report demonstrates that severe fluctuations in TH levels may lead to acute HF,which can completely recover with timely thyroid hormone *** addition,our findings highlight the importance of routinely detecting cardiac function in patients treated with radioactive iodine.

关键词： Heart failure hypothyroid cardiomyopathy Hormone replacement therapy Radioactive iodine therapy Case report

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