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Preservation of laryngeal function in treatment of hypopharyngeal carcinoma

Chinese Medical Journal 2002年第6期115卷 892-896,154页

作者：王天铎李学忠卢永田于振坤山东大学齐鲁医院耳鼻咽喉科济南250012

OBJECTIVE: To study the surgical technique and results of laryngeal function preservation in treatment of hypopharyngeal carcinoma. METHODS: A retrospective review of 305 patients with malignant neoplasms of the hypopharynx (279 males, 26 females, age ranging from 14 to 77 years) was performed from 1978 to 1996. In the 305 patients (stage I, n = 6; stage II, n = 12; stage III, n = 82; stage IV, n = 205), the sites of origin were pyriform sinus (n = 234), postcricoid (n = 21), posterior pharyngeal wall (n = 35) and superior hypopharynx (n = 15). Of the 305 patients, 206 (67.54%, stage I, n = 6; stage II, n = 12; stage III, n = 65; stage IV, n = 123) were surgically treated with laryngeal function preserved and 99 (32.46%, stage III, n = 17; stage IV, n = 82) had no laryngeal function *** had 55-75 Gy radiotherapy according to their need. RESULTS: A total of 206 patients (67.54%) were surgically treated with laryngeal function preserved, totally (voice, respiration and deglutition) in 139 (67.5%) and partially (voice and deglutition) in 67 (32.5%). 99 patients (32.46%) had no laryngeal function preserved. The overall 5-year survival rate of the 305 patients was 44.8%, which segregated to 83% (stage I), 71% (stage II), 58% (stage III), and 36% (stage IV). The 5-year survival of the laryngeal function preserved group was 48% (n = 66), the rate of complications 28% (n = 58) and the rate of residual tumor 5.8% (n = 12), compared with the no laryngeal function preserved group 37% (n = 20), 31.3% (n = 31), and 6% (n = 6) (P > 0.05). CONCLUSION: Only a small proportion of patients (31/305, 10%) with hypopharyngeal carcinoma who require total laryngectomy and preservation of the laryngeal function is feasible for eradication of tumor and preservation of laryngeal function.

关键词： Adolescent Adult Aged Female Humans hypopharyngeal neoplasms Hypopharynx Larynx Male Middle Aged Survival Rate

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Applied anatomy of the submental island flap and its clinical application in the repair of defects following hypopharyngeal carcinoma resection

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2015年第1期1卷 -页

作者： Xi Chen Han Zhou Yong-Jie Zhang Lin Yin Mei-Ping Lu Guang-Qian Xing Zi-Ping Lin Department of Otorhinolaryngology The First Affiliated Hospital Nanjing Medical University Nanjing 210029 China Department of Human Anatomy School of Basic Medical Sciences Nanjing Medical University Nanjing 210029 China Department of Stomatology The First Affiliated Hospital Nanjing Medical University Nanjing 210029 China

Objective: To explore the feasibility of the submental island flap in the repair of hypopharyngeal ***: We collected wet specimens of fresh cadaveric heads from the Han Chinese adult population for applied anatomy of the submental island flap, and followed five patients with pyriform sinus carcinoma after reconstruction surgery using submental island ***: We found that the average length and width of the submental island flaps were (65.20 ± 11.69) mm and (46.70 ± 6.59) mm, *** skin flap in all five patients survived after surgery, and tracheal tubes and gastric tubes were removed 7-36 days after *** were followed up for 24-42 months, pharyngeal flaps grew well, and speech and swallowing functions were ***: The submental island flap is a preferred material for the repair of hypopharyngeal defects after hypopharyngeal carcinoma resection, because of good blood supply, easy harvesting, and high survival rate.

关键词： Submental island flap Submental artery Submental vein hypopharyngeal neoplasms Reconstructive surgical procedures

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