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Mathematic Model of Unsteady Penetration Mass Transfer in Randomly Packed hollow fiber membrane module

Chinese Journal of Chemical Engineering 2004年第2期12卷 185-190页

作者：张秀莉张泽廷张卫东郝欣 College of Chemical Engineering Beijing University of Chemical Technology Beijing 100029 China

Based on the membrane-based absorption experiment of CO2 into water, shell-side flow distribution and mass transfer in a randomly packed hollow fiber module have been analyzed using subchannel model and unsteady penetration mass transfer theory. The cross section of module is subdivided into many small cells which contains only one hollow-fiber. The cross sectional area distribution of these cells is presented by the normal probability density distribution function. It has been obtained that there was a most serious non-ideal flow in shell side at moderate mean packing density, and the large amount of fluid flowed and transferred mass through a small number of large voids. Thus mass transfer process is dominated by the fluid through the larger void area. The mass transfer process in each cell is described by the unsteady penetration theory. The overall mass transfer coefficient equals to the probability addition of the mean mass transfer coefficient in each cell. The comparisons of the values calculated by the model established with the empirical correlations and the experimental data of this work have been *** predicted overall mass transfer coefficients are in good agreement with experimental data.

关键词： hollow fiber membrane module mass transfer membrane separation mathematic model

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Introducing 3D-potting:a novel production process for artificial membrane lungs with superior blood flow design

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Bio-Design and Manufacturing 2022年第1期5卷 141-152页

作者： Fellx Hesselmann Jannls M.Focke Peter C.Schlansteln NIklas B.Steuer Andreas Kaesler Sebastlan D.Relnartz Thomas Schmltz-Rode Ulrlch SteInselfer Sebastlan V.Jansen Jutta Arens Department of Cardiovascular Engineering Instituteof Applied Medical EngineeringHelmholtz.InstituteRWTH Aachen UniversityPauwelsstrasse 2052074 AachenGermany Department of Diagnostic and Interventional Radiology Uniklinik RWTH AachenPauwelsstrasse 3052074 AachenGermany Department of Biomechanical Engineering Faculty of EngineeringTechnology University of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands

Currently,artificial-membrane lungs consist of thousands of hollow fiber membranes where blood flows around the fibers and gas flows inside the fibers,achieving diffusive gas *** both ends of the fibers,the interspaces between the hollow fiber membranes and the plastic housing are filled with glue to separate the gas from the blood *** a uniaxial centrifugation process,the glue forms the“potting.”The shape of the cured potting is then determined by the centrifugation process,limiting design possibilities and leading to unfavorable stagnation zones associated with blood *** this study,a new multiaxial centrifugation process was developed,expanding the possible shapes of the potting and allowing for completely new module designs with potentially superior blood flow guidance within the potting ***-phase simulations of the process in conceptual artificial lungs were performed to explore the possibilities of a biaxial centrifugation process and determine suitable parameter sets.A corresponding biaxial centrifugation setup was built to prove feasibility and experimentally validate four conceptual designs,resulting in good agreement with the *** summary,this study shows the feasibility of a multiaxial centrifugation process allowing greater variety in potting shapes,eliminating inefficient stagnation zones and more favorable blood flow conditions in artificial lungs.

关键词： Potting process Flow design membrane lung Artificial lung hollow fiber membrane module Manufacturing

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