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Regulation of innate and adaptive immunity using herbal medicine:benefits for the COVID-19 vaccination

Acupuncture and herbal Medicine 2022年第3期2卷 196-206页

作者： Xuan Li Nuttapong Wichai Jiabao Wang Xiuping Liu Huimin Yan Yu Wang Mingchi Luo Shengyuan Zhou Kai Wang Lin Li Lin Miao State Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina Faculty of Pharmacy Mahasarakham UniversityMahasarakhamThailand Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae Ministry of EducationTianjin University of Traditional Chinese MedicineTianjinChina Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine TianjinChina

Vaccination is a major achievement that has become an effective prevention strategy against infectious diseases and active control of emerging pathogens *** response to the coronavirus disease 2019(COVID-19)pandemic,several diverse vaccines against severe acute respiratory syndrome coronavirus 2 have been developed and deployed for use in a large number of individuals,and have been reported to protect against symptomatic COVID-19 cases and ***,the application of vaccines has a series of limitations,including protective failure for variants of concern,unavailability of individuals due to immune deficiency,and the disappearance of immune protection for increasing infections in vaccinated *** aspects raise the question of how to modulate the immune system that contributes to the COVID-19 vaccine protective *** medicines are widely used for their immune regulatory abilities in *** attractively,herbal medicines have been well accepted for their positive role in the COVID-19 prevention and suppression through regulation of the immune *** review presents a brief overview of the strategy of COVID-19 vaccination and the response of the immune system to vaccines,the regulatory effects and mechanisms of herbal medicine in immune-related macrophages,natural killer cells,dendritic cells,and lymphocytes T and B cells,and how they help vaccines *** in the article,the potential role and application of herbal medicines in the most recent COVID-19 vaccination are *** article provides new insights into herbal medicines as promising alternative supplements that may benefit from COVID-19 vaccination.

关键词： COVID-19 herbal medicines Immunity Dendritic cells Macrophage Vaccine protection

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