检索结果-南通市图书馆

Progress in Use of Natural Products and Their Active Components against Helicobacter pylori

Advances in Microbiology 2016年第14期6卷 1091-1129页

作者： Alejandro Venegas Jorge Hantar Touma Jessica Bravo Guillermo Perez-Perez Centro de Investigación Biomédica Facultad de Medicina Universidad Diego Portales Santiago Chile Departments of Medicine and Microbiology New York Langone Medical Center NYU New York USA

Helicobacter pylori is considered the main etiological agent of gastritis, ulcers, and gastric carcinoma. It colonizes human gastric mucosa quite efficiently. Fifty % of the world population is actually infected. Since H. pylori discovery in 1982, it is well known the sensitivity of several H. pylori strains to a number of antibiotics when these are assayed in vitro. However, eradication therapies with a single antibacterial agent have failed. Recently, triple, quadruple, sequential, concomitant and hybrid therapies which include antibiotics and a proton pump inhibitor show improved eradication rate and low side effects. However, new problems have emerged. Antimicrobial resistance to the common antibiotics used has become a problem in both developed and developing countries. In particular, H. pylori clarithromycin- and metronidazole-resistant strains are a major problem in countries where H. pylori is highly prevalent. Thus, the widespread use of antibiotics is not economically feasible and might increase difficulties in the treatment of H. pylori. At present, there are no vaccines available in the market. As an alternative, effective non-antibiotic compounds should be highly desirable since their use may be safer and suitable to eradicate H. pylori. The first step in this direction has been to study the effect of medicinal herbs and natural products, such as green tea, ginseng, garlic, propolis, and probiotics, then identify their active components such as polyphenols, antioxidants, purify them, and finally test them using in vitro and in vivo H. pylori growth assays. Some of them have been quite effective. The topics related to alternative therapies for H. pylori infections and current status of their use will be discussed in the present review.

关键词： H. pylori Growth Inhibition Natural Products herb infusions Phytochemicals

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：