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A hiddenly high hepatitis c virus related liver disease burden among chinese patients with non-liver disease complaints: A hospital based study from 2013 to 2017

引用

Asian Pacific Journal of Tropical Medicine 2018年第2期11卷 171-176页

作者： Hua-Ping Huang Guo-Sheng Yuan Yu-chen Zhou cheng-Guang Hu Jun-Wei Liu Shuai Yuan Yu-Rong Qiu Yi-Ping Li Yong-Yuan Zhang Yuan-Ping Zhou Department of Infectious Diseases and Hepatology Unit Nanfang HospitalSouthern Medical University Department of Respiratory Diseases The First Affiliated Hospital of Hainan Medical University Department of Hepatobiliary Surgery Nanfang HospitalSouthern Medical University Laboratory Medicine center Nanfang HospitalSouthern Medical University Institute of Human Virology and Key Laboratory of Tropical Disease control of Ministry of Education Zhongshan School of MedicineSun Yat-sen University HBVtech

Objective: To determine the frequency of anti-HcV antibody positivity in patients with nonliver disease complaints, to explore whether anti-HcV positive patients had been properly advised and visited hepatologists for further assessments, and to investigate their clinical characteristics as well as the HcV treatment ***: A hospital based survey of nonliver disease patients with anti-HcV positive and their attending physicians was conducted to determine: *** the patients adequately advised of the implication of anti-HcV positive finding; *** what extent the patients were aware of potential chronic liver disease associated with HcV infection and whether they sought for further assessments and care of ***: A total of 295 294 non-liver disease patients were tested for anti-HcV antibody, and 2 778 of them were found to be positive(0.94%).However, only 45.10%(1 253/2 778) of the anti-HcV antibody(+) patients were referred to hepatologists and received HcV RNA *** addition, 34.10%(312/915) and 1.42%(13/915) of them had already advanced to cirrhosis and hepatocellular carcinoma(Hcc), *** analysis showed that the patients who declined antiviral therapy were older, with lower education and lower income, possessed poorer knowledge on the risk of chronic hepatitis c, and had more severe liver ***, 65% of the surveyed physicians did not know the genotype-guided treatment duration suggested by the ***, 22% of the surveyed physicians did not know the standard assays for the diagnosis of HcV ***: Our findings highlight the challenge and hidden enormous burden of chronic HcV infection among patients with non-liver disease complaints in china.

关键词： china HcV hepatitis c antibody Diagnosis Treatment status Survey

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