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Qualitative and semi-quantitative analysis of health-care pharmaceutical products using laser-induced breakdown spectroscopy

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Journal of Pharmaceutical Analysis 2019年第1期9卷 20-24页

作者： Sobia Nisar Ghulam Dastgeer Muhammad Shafiq Muhammad Usman Department of Industrial Engineering University of Engineering and Technology Department of Physics & Astronomy and Graphene Research Institute Sejong University Department of Engineering University of Sannio Centre for Optical and Electromagnetic Research South China Academy of Advanced Optoelectronics South China Normal University

Laser-induced breakdown spectroscopy(LIBS) is a sensitive optical technique that is capable of rapid multi-elemental analysis. The development of this technique for elemental analysis of pharmaceutical products may eventually revolutionize the field of human health. Under normal circumstances, the elemental analysis of pharmaceutical products based on chemical methods is time-consuming and complicated. In this investigation, the principal aim is to develop an LIBS-based methodology for elemental analysis of pharmaceutical products. This LIBS technique was utilized for qualitative as well as quantitative analysis of the elements present in Ca-based tablets. All the elements present in the tablets were detected and their percentage compositions were verified in a single shot, using the proposed instrument. These elements(e.g., Ca, Mg, Fe, Zn, and others) were identified by the wavelengths of their spectral lines, which were verified using the NIST database. The approximate amount of each element was determined based on their observed peaks and the result was in exact agreement with the content specification. The determination of the composition of prescription drug for patients is highly important in numerous circumstances. For example, the exploitation of LIBS may facilitate elemental decomposition of medicines to determine the accuracy of the stated composition information. Moreover, the approach can provide element-specific, meaningful, and accurate information related to pharmaceutical products.

关键词： Laser-induced breakdown spectroscopy Elements identification health-care pharmaceutics Qualitative analysis Quantitative analysis

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The Preparation of Fragrance and health-care Microcapsule Agent and Its Application on Fabrics

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Journal of Donghua University(English Edition) 2007年第3期24卷 337-340页

作者：王俊华蔡再生 College of Chemical and Chemistry Engineering Donghua University

The technology of microcapsule was employed in this paper to prepare fragrant microcapsule agent, in which the core material was lavender oil, and the wall material polyurethane was formed from a reaction with 2, 4-tolylene diisocyanate （ TDI ） and poly （ ethylene glycol）（PEG） by interracial polymerization method. Through single factor and orthogonal experiments, the optimum technology conditions have been got as follows： the molecular weight of PEG 400, core/wall ration 1 ： 2, disperser sodium alginate （SA） 0.15%, emulsifier Poly（vinyl alcohol）（PVA） 1%, emulsifying speed 9 500 r/min, emulsifying time 5 min and reaction time 2 h. The microcapsule fragrant agent, prepared under the optimum conditions, was applied on the fabrics and a kind of good control-released fragrant fabric with health-care function was obtained.

关键词： microcapsule polyurethane lavender oil health-care fragrant fabrics

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health-care needs of remitted patients with bipolar disorder: A comparison with schizophrenia

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World Journal of Psychiatry 2016年第4期6卷 431-441页

作者： Rajarshi Neogi Subho Chakrabarti Sandeep Grover Department of Psychiatry Postgraduate Institute of Medical Education and Research (PGIMER)

AIM To investigate health-care needs and their correlates among patients with remitted bipolar disorder(BD) compared to patients with remitted schizophrenia. METHODS Outpatients with BD(n = 150) and schizophrenia(n = 75) meeting clearly defined remission criteria were included in the study along with their relatives. Diagnostic ascertainment was carried out using the Mini International Neuropsychiatric Interview. Demographic and clinical details were recorded using structured formats. Residual symptoms were assessed using standardized scales. health-care needs were assessed on two separate scales. The principal instrument employed to assess health-care needs was the Camberwell Assessment of Need-Research version(CAN-R). To further evaluate health-care needs we felt that an additional instrument, which was more relevant for Indian patients and treatment-settings and designed to cover those areas of needs not specifically covered by the CAN-R was required. This instrument with a structure and scoring pattern similar to the CAN-R was used for additional evaluation of needs. Patients' level offunctioning was assessed using the Global Assessment of Functioning Scale and their quality of life(QOL) using the World health Organization Quality Of Life-BREF version in *** An average of 6-7 needs was reported by patients with BD as well as their relatives. Commonly reported needs were in the areas of economic and welfare needs, informational needs, social needs and the need for treatment. According to the CAN-R, both patients and relatives reported that more than 60% of the total needs were being met. However, over 90% of the needs covered by the additional evaluation were unmet according to patients and relatives. Needs in the areas of economic and welfare-benefits, information, company, daytime activities and physical health-care were largely unmet according to patients and relatives. Total, met and unmet needs were significantly higher for schizophrenia, but the m

关键词： health-care needs Bipolar disorder Schizophrenia Remission Patients Relatives

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Family responsibility dynamics for young adults in transition to adult health care

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Journal of Diabetes Mellitus 2013年第3期3卷 139-144页

作者： Pat Rapley Gwen Babel Joey Kaye Suzanne Brown Adjunct Senior Lecturer Curtin University and Centre for Nursing Research Sir Charles Gairdner Hospital Perth Australia Department of Endocrinology and Diabetes Sir Charles Gairdner Hospital Perth Australia

Aim: To explore family responsibility dynamics, metabolic control, clinic attendance, and emergency admissions when young adults (YA) with type 1 diabetes transition to an adult hospital. Method: A longitudinal mixed method design with two study groups (parents, n = 28;YA intervention group, n = 23) and a YA comparison group (n = 20). Sample recruited from an outpatient diabetes centre. Demographic, clinic attendance, emergency admissions, biodata, and the Diabetes Family Responsibility Questionnaire (DFRQ) were completed on entry and sixmonths later as part of an 18-month trial of a diabetes transition coordinator (DTC). The selfreport DFRQ were analyzed using derived parent-child dyadic variables to explore differences at baseline and end of study using Wilcoxon Signed Rank Test. The relationship between metabolic control and the DFRQ patterns was explored using Spearman’s rho. Results: On completion of the study, the change in HBA1Cfor both adolescent groups was not significant but was less than ideal for 25% of adolescents in the study. The YA intervention group had significantly fewer missed appointments between them compared to the comparison group. The DFRQ indicated that the derived parent-child dyadic variable of task-discordance increased during the study. Conclusion: The clinically relevant diabetes-task dissonance between parents and young adults offers a challenge and a diagnostic opportunity for diabetes educators.

关键词： Diabetes health-care Transition Parent Adolescent Transition Coordinator

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A Mobile Cloud-Based ehealth Scheme

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Computers, Materials & Continua 2020年第4期63卷 31-39页

作者： Yihe Liu Aaqif Afzaal Abbasi Atefeh Aghaei Almas Abbasi Amir Mosavi Shahaboddin Shamshirband Mohammed A.A.Al-qaness Data Recovery Key Laboratory of Sichuan Province College of Computer Science and AINeijiang Normal UniversityNeijiang641100China Department of Software Engineering Foundation UniversityIslamabad44000Pakistan Department of Communication Faculty of Social SciencesUniversity of TehranTehran***Iran Department of Computer Science International Islamic UniversityIslamabad46000Pakistan Institute of Research and Development Duy Tan UniversityDa Nang550000Vietnam Kalman Kando Faculty of Electrical Engineering Obuda UniversityBudapest1034Hungary School of the Built Environment Oxford Brookes UniversityOxfordOX30BPUK Department for Management of Science and Technology Development Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of Information Technology Ton Duc Thang UniversityHo Chi Minh CityVietnam School of Computer Science Wuhan UniversityWuhan430072China

Mobile cloud computing is an emerging field that is gaining popularity across borders at a rapid ***,the field of health informatics is also considered as an extremely important *** work observes the collaboration between these two fields to solve the traditional problem of extracting Electrocardiogram signals from trace reports and then performing *** developed system has two front ends,the first dedicated for the user to perform the photographing of the trace *** the photographing is complete,mobile computing is used to extract the *** the signal is extracted,it is uploaded into the server and further analysis is performed on the signal in the *** this is done,the second interface,intended for the use of the physician,can download and view the trace from the *** data is securely held using a password-based authentication *** system presented here is one of the first attempts at delivering the total solution,and after further upgrades,it will be possible to deploy the system in a commercial setting.

关键词： Cloud computing electrocardiograms health-care signal analysis signal processing

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Performance Evaluation of healthcare Monitoring System over Heterogeneous Wireless Networks

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E-health Telecommunication Systems and Networks 2012年第3期1卷 27-36页

作者： Sabato Manfredi Faculty of Engineering University of Naples Federico II Napoli Italy

The wide diffusion of healthcare monitoring systems allows continuous patient to be remotely monitored and diagnosed by doctors. The problem of congestion, namely due to the uncontrolled increase of traffic with respect to the network capacity, is one of the most common phenomena affecting the reliability of transmission of information in any network. The aim of the paper is to build a realistic simulation environment for healthcare system including some of the main vital signs model, wireless sensor and mesh network protocols implementation. The simulator environment is an efficient mean to analyze and evaluate in a realistic scenario the healthcare system performance in terms of reliability and efficiency.

关键词： Modeling Simulation and Management of health-care Systems Applications of Information and Communication Technologies to health-care Management E-health Remote health Monitoring Telemedicine Chronic Disease Management

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Predictors of Clostridium difficile infection severity in patients hospitalised in medical intensive care

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World Journal of Gastroenterology 2013年第44期19卷 8034-8041页

作者： Nagham Khanafer Abdoulaye Touré Cécile Chambrier Martin Cour Marie-Elisabeth Reverdy Laurent Argaud Philippe Vanhems Laboratory of Epidemiology and Public health CNRS UMR 5558 University of Lyon 69 373 Lyon France Epidemiology and Infection Control Unit Edouard Herriot Hospital Hospices Civils of Lyon 69437 Lyon France Clinical Nutrition Intensive care Unit Croix Rousse Hospital Hospices Civils of Lyon69317 Lyon France INSERM Unit 1060 INRA 1235 University of Lyon 69921 Oullins France Medical Intensive care Unit Edouard Herriot Hospital Hospices Civils of Lyon 69437 LyonFrance Microbiology Laboratory Hospices Civils of Lyon 69677 Bron France

AIM:To describe and analyse factors associated with Clostridium difficile infection(CDI)severity in hospitalised medical intensive care unit ***:We performed a retrospective cohort study of 40 patients with CDI in a medical intensive care unit(MICU)at a French university *** include patients hospitalised between January 1,2007and December 31,*** on demographics characteristics,past medical history,CDI description was *** to risk factors associated with CDI within 8 wk before CDI was recorded,including previous hospitalisation,nursing home residency,antibiotics,antisecretory drugs,and surgical ***:All included cases had their first episode of *** mean incidence rate was 12.94 cases/1000admitted patients,and 14.93,8.52,13.24,19.70,and8.31 respectively per 1000 admitted patients annually from 2007 to *** age was 62.9[interquartile range(IQR)55.4-72.40]years,and 13(32.5%)were *** length of MICU stay was 14.0d(IQR 5.0-22.8).In addition to diarrhoea,the clinical symptoms of CDI were fever(>38℃)in 23 patients,abdominal pain in 15 patients,and ileus in 1 *** duration of diarrhoea was 13.0(8.0-19.5)*** addition to diarrhoea,the clinical symptoms of CDI were fever(>38℃)in 23 patients,abdominal pain in 15 patients,and ileus in 1 *** to CDI,38patients(95.0%)were exposed to antibiotics,and 12(30%)received at least 4 ***,3rdgeneration cephalosporins,coamoxiclav and tazocillin were prescribed most frequently(65%,55%,40%and 37.5%,respectively).The majority of cases were hospital-acquired(n=36,90%),with 5 cases(13.9%)being *** patients had severe *** crude mortality rate within 30 d after diagnosis was 40%(n=16),with 9 deaths(9 over 16;56.3%)related to *** our 40 patients,15(37.5%)had severe *** logistic regression showed that male gender[odds ratio(OR):8.45;95%CI:1.06-67.16,P=0.044],rising serum C-reactive protein levels(OR=

关键词： Clostridium difficile health-care associated infection Hospital-acquired infection Intensive care unit Nosocomial infection Severe Clostridium difficile infection

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An Integrated Emergency Response Tool for Developing Countries:Case of Uganda

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Journal of Electronic & Information Systems 2021年第1期3卷 7-12页

作者： Swaib Kyanda Kaawaase Rodney Ekisa Simon Networks Department College of Computing and Information SciencesMakerere UniversityKampalaUganda

This paper presents a First responder emergency response tool(EMApp)as a step towards achieving integrated emergency care in developing countries,the case of *** EMApp prototype has potential to support health emergency response from various emergency *** innovation is in line with strategic plans to embrace technologies towards the establishment of integrated social services such as emergency healthcare services(EHS)in *** describe the prototype and provide its functionalities that can be further enhanced to enable access to emergency services and save *** possible assumptions,potential challenges and recommendations to implement and deployment of such a system are pro*** is currently no such integrated emergency response system in Uganda as is the case in many other developing *** future studies,there is need to deploy the tool and assess its impact on the communities.

关键词： Emergency-response E-health E-infrastructure E-service health-care

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