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The Future Challenges of Population Health in China:A Projection of the Major Health Problems and Life Expectancy——China,2015-2050

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China CDC weekly 2022年第13期4卷 276-279页

作者： Jiangmei Liu Bo Jiang Yanhong Fu Zhuo Wang Min Liu Peng Yin Maigeng Zhou National Center for Chronic and Non-Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Department of Epidemiology and Health Statistics Xiangya School of Public HealthCentral South UniversityChangshaChina Department of Chronic and Non-communicable Disease Control and Prevention Sichuan Center of Disease Control and PreventionChengduChina

According to the Seventh National Population Census in 2020,the life expectancy of the Chinese population has been gradually rising in the past 10 years(1).With China’s industrialization,urbanization,and rapidly aging population,behavioral changes,and environmental factors have a growing impact on Health.The strategy based on“curing disease”cannot meet the public’s Health needs.

关键词： Population Challenges Health

Impacts of weaning weights and mycotoxin challenges on jejunal mucosa-associated microbiota,intestinal and systemic Health,and growth performance of nursery pigs

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Journal of Animal Science and Biotechnology 2022年第5期13卷 1440-1457页

作者： D.M.Holanda S.W.Kim Department of Animal Science North Carolina State UniversityRaleigh 27695USA

Background:This study aimed at investigating the effects of mycotoxin challenge on the growth and physiology of nursery pigs with different weaning weights.Results:At weaning,10 pigs were euthanized to collect jejunal mucosa and 90 pigs were assigned following a randomized complete block design in a 2×2 factorial arrangement of treatments with 3 pigs per pen.Factors were:weaning weight(light:body weight,BW9.0 kg);and dietary mycotoxins(supplementation of 0.2 mg/kg aflatoxins,2.0 mg/kg deoxynivalenol).All diets had titanium dioxide as an external marker at 0.5%.Growth performance and fecal score were recorded until pigs achieved 20 kg BW(light pigs average BW=21.1 kg and heavy pigs average BW=20.5 kg).Pigs were sampled for blood,ileal digesta,jejunal tissue and mucosa at 20 kg BW.Data were analyzed using the mixed procedure of SAS.At weaning,light pigs had decreased(PHealth due to weaning stress,whereas mycotoxins diminished the Health and growth of nursery pigs regardless of weaning weight.

关键词： Growth Health Mycotoxins Nursery pig Weaning weight

Statement on Establishment of A Provisional Health Based Guidance Value for Dietary Exposure to Cadmium in China

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China CDC weekly 2023年第22期5卷 499-503页

作者： Jinfang Sun Yi Shao Gengsheng He Yongning Wu Key Laboratory of Environmental Medicine Engineering Ministry of EducationSchool of Public HealthSoutheast UniversityNanjing CityJiangsu ProvinceChina Department of Epidemiology and Biostatistics School of Public HealthSoutheast UniversityNanjing CityJiangsu ProvinceChina Research Unit of Food Safety Chinese Academy of Medical SciencesNHC Key Laboratory of Food Safety Risk AssessmentChina National Center for Food Safety Risk AssessmentBeijingChina School of Public Health/Key Laboratory of Public Health Safety Ministry of EducationDepartment of Nutrition and food scienceFudan UniversityShanghaiChina

The National Health Commission of the People’s Republic of China and the State Administration for Market Regulation have issued the National Food Safety Standard(GB2762-2022),which delineates the maximum limits(ML)of contaminants in food.This standard will be implemented on June 30,2023.It currently maintains the ML of cadmium in rice(including unhusked rice,husked rice,polished rice)at 0.2 mg/kg,a value first established 40 years ago in GBn238-1984.

关键词： maintain Health cadmium

Assessment of performance for a key indicator of One Health:evidence based on One Health index for zoonoses in Sub-Saharan Africa

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Infectious Diseases of Poverty 2022年第5期11卷 74-86页

作者： Han‑Qing Zhao Si‑Wei Fei Jing‑Xian Yin Qin Li Tian‑Ge Jiang Zhao‑Yu Guo Jing‑Bo Xue Le‑Fei Han Xiao‑Xi Zhang Shang Xia Yi Zhang Xiao‑Kui Guo Kokouvi Kassegne Department of Infectious and Tropical Diseases School of Global HealthChinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghai 200025People’s Republic of China One Health Center Shanghai Jiao Tong University-The University of EdinburghShang‑hai 200025People’s Republic of China National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention(Chinese Center for Trop‑ical Diseases Research) National Health Commission of the People’s Republic of China(NHC)Key Laboratory of Parasite and Vector BiologyWHO Collaborat‑ing Center for Tropical DiseasesShanghai 200025People’s Republic of China.

Background:Zoonoses are public Health threats that cause severe damage worldwide.Zoonoses constitute a key indicator of One Health(OH)and the OH approach is being applied for zoonosis control programmes of zoonotic diseases.In a very recent study,we developed an evaluation system for OH performance through the global OH index(GOHI).This study applied the GOHI to evaluate OH performance for zoonoses in sub-Saharan Africa.Methods:The framework for the OH index on zoonoses(OHIZ)was constructed including five indicators,15 subindicators and 28 datasets.Publicly available data were referenced to generate the OHIZ database which included both qualitative and quantitative indicators for all sub-Sahara African countries(n=48).The GOHI algorithm was used to estimate scores for OHIZ.Indicator weights were calculated by adopting the fuzzy analytical hierarchy process.Results:Overall,five indicators associated with weights were generated as follows:source of infection(23.70%),route of transmission(25.31%),targeted population(19.09%),capacity building(16.77%),and outcomes/case studies(15.13%).Following the indicators,a total of 37 sub-Sahara African countries aligned with OHIZ validation,while 11 territories were excluded for unfit or missing data.The OHIZ average score of sub-Saharan Africa was estimated at 53.67/100.The highest score was 71.99 from South Africa,while the lowest score was 40.51 from Benin.It is also worth mentioning that Sub-Sahara African countries had high performance in many subindicators associated with zoonoses,e.g.,surveillance and response,vector and reservoir interventions,and natural protected areas,which suggests that this region had a certain capacity in control and prevention or responses to zoonotic events.Conclusions:This study reveals that it is possible to perform OH evaluation for zoonoses in sub-Saharan Africa by OHIZ.Findings from this study provide preliminary research information in advancing knowledge of the evidenced risks to strengthen strategies for effective control of zoonoses and

关键词： One Health index One Health performance Zoonoses Sub-Saharan Africa

Scaling-up filariasis lymphoedema management into the primary Health care system in Kerala State, Southern India: a case study in Healthcare equity

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Infectious Diseases of Poverty 2022年第1期11卷 74-81页

作者： Suma T.Krishnasastry Charles D.Mackenzie Rajeev Sadanandan Filariasis Research Unit WHO Collaborating Center for LF MMDPLymphatic Filariasis Morbidity Management and Disability PreventionDepartment of Internal MedicineGovt.T.D.Medical College HospitalKerala University of Health SciencesAlappuzha688005India NTD Support Center Task Force for Global HealthAtlantaGA30030USA Health Systems Transformation Platform New Delhi110070India

Background:Lymphatic filariasis(LF)remains one of the world’s most debilitating parasitic infections and is a major contributor to poor Health in many endemic countries.The provision of continuing care for all those affected by LF and its consequences is an important component of the United Nations’Sustainable Development Goals.The aim of this study is to integrate lymphedema care into the primary Health care system of the State by developing lymphedema clinics at each district,through training of Health personnel to fulfill WHO recommendation for morbidity management and disability prevention.Methods:Selected Health care providers from all the districts in Kerala State of India participated in intensive training sessions endorsed by the State’s Health administration.The six training sessions(from 5 June 2017 to 25 May 2018)included appropriate self-care information and development of individual plans for each participating institution to provide instruction and care for their lymphoedema patients.The learning achieved by attendees was assessed by pre-and post-training tests.The number of lymphoedema patients receiving care and instruction from the post-training activities of each participating institution was assessed from local records,6 months after the conclusion of the training sessions.Results:One hundred and eighty-four medical personnel(91 doctors and 93 nurses)from 82 medical institutions were trained which quickly led to the establishment of active lymphoedema clinics providing the essential package of care(EPC)for lymphoedema patients at all the participating institutions.Six months after the training sessions the number of previously unidentified lymphoedema patients registered and receiving care at these clinics ranged from 296 to almost 400 per clinic,with a total of 3,477 new patients receiving training in EPC.Conclusions:Generalist Health personnel,when appropriately trained,can provide quality lymphoedema care in public Health settings and patients when provided services close to their home,are w

关键词： Lymphatic filariasis Health equity India Lymphoedema Global program to eliminate lymphatic filariasis

Dietary coated essential oil and organic acid mixture supplementation improves Health of broilers infected with avian pathogenic Escherichia coli

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Animal Nutrition 2023年第1期12卷 245-262页

作者： Van Hieu Pham Waseem Abbas Jinyu Huang Fangshen Guo Kaichen Zhang Linhua Kong Wenrui Zhen Yuming Guo Zhong Wang State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural UniversityBeijing100193China Faculty of Animal Science and Veterinary Medicine Thai Nguyen University Agriculture and ForestryThai NguyenViet Nam Menon Animal Nutrition Technology Co.Ltd. Shanghai201807China Tengzhou Heyi Food Co.Ltd. Zaozhuang277000China

Colibacillosis caused by avian pathogenic Escherichia coli(APEC)is a very prevalent disease in poultry farms in China.The exploration of effective non-antibiotic substances is of great significance for the control of APEC infections.This experiment evaluated the efficacy of coated essential oil and organic acid(EOA)supplementation to prevent E.coli O78 infection in broiler chickens.A total of 288 one-day-old male broiler chicks were randomly distributed into 4 groups with 6 replicates per group.Chickens were fed a diet either supplemented with EOA(500 mg/kg feed)or not,and either uninfected or infected with E.coli O78 intratracheally.Results showed that E.coli O78 infection reduced body weight gain,increased mortality and the ratio of feed to gain along with cecal and liver E.coli load,damaged gut mucosa,induced local and systemic inflammation,and altered cecal microbial composition,diversity and function(P<0.05).Supplemental EOA improved feed conversion efficiency,lowered gross lesion scores and cecal E.coli population,enhanced intestinal goblet cells and serum IgG concentration,and tended to decrease serum IL-12 production(P<0.05).Essential oil and organic acid addition downregulated IFN-γmRNA,tended to decrease mucin-2 mRNA levels while upregulating IL-10 mRNA,and tended to increase ZO-1 gene expression in the jejuna of infected birds at 7 d after E.coli O78 challenge(P<0.05).The 16S rRNA gene sequencing indicated that both EOA addition and E.coli O78 challenge altered the diversity and composition of the cecal microbiota community.Furthermore,infected birds fed EOA showed decreased Bacteroidetes and genus Lactobacillus abundance compared with the infected control.LEfSe analysis showed that Firmicutes,Ruminococcaceae,Clostridiales,Clostridia,Lactobacillus,Lactobacilaceae,and cc-115 were enriched in the non-infected but EOA-treated group(P<0.05).Collectively,dietary EOA supplementation could mildly alleviate E.coli-induced gut injury and inflammation.

关键词： Encapsulated essential oil and organic acid mixture Avian pathogenic Escherichia coli Health Broiler chicken

Exploring the social,ethical,legal,and responsibility dimensions of artificial intelligence for Health-a new column in Intelligent Medicine

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Intelligent Medicine 2022年第2期2卷 103-109页

作者： Achim Rosemann Xinqing Zhang Centre for Computing and Social Responsibility De Montfort UniversityLeicesterUnited Kingdom Department of Sociology Philosophy and AnthropologyUniversity of ExeterUnited Kingdom School of Humanities and Social Sciences Peking Union Medical College&Chinese Academy of Medical SciencesBeijing 100005China

This essay is the starting point of a new column in Intelligent Medicine that invites interdisciplinary perspectives on the social,ethical,legal,and responsibility aspects of the use of artificial intelligence(AI)in medicine and Health care.Papers in this column will examine the practical,conceptual,and policy dimensions of the use of AI for Health-related purposes from comparative and international perspectives.We invite contributions from around the world in all application areas of AI for Health,including Health care,Health research,drug development,Health care system management,as well as public Health and public Health surveillance.The column aims to provide a forum for reflective and critical scholarship that contributes to the ongoing academic and policy debates about the development,use,governance,and implications of AI in medical and Health care settings.To launch the column,we first provide an overview of recent approaches that have been developed to identify and address the effects and potential impacts of science and technology innovations on human societies and the environment.These include ethical,legal,and social implications/aspects(ELSI/A)research,responsible research and innovation(RRI),sustainability transitions research,and the use of international standard-setting instruments for responsible and open science issued by the United Nations Educational,Scientific,and Cultural Organization(UNESCO),the World Health Organization(WHO),and other international bodies.In Part Two of this essay,we discuss some of the central challenges that arise with regard to the integration of AI and big data analytics in medical and Health care settings.This includes concerns regarding(i)the control,reliability,and trustworthiness of AI systems,(ii)privacy and surveillance,(iii)the impact of AI and automation on Health care staffemployment and the nature of clinical work,(iv)the effects of AI on Health inequalities,justice,and access to medical care,and(v)challenges related to regulation and governance.We end the ess

关键词： Artificial intelligence Health Ethical,legal and social implications Responsible research and innovation Global ethics Governance of emerging technologies

Addressing Environmental Health Challenges for Sustainable Development in China

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China CDC weekly 2023年第32期5卷 715-719页

作者： Shilu Tong Yuebin Lyu Jiao Wang Xiaoming Shi National Institute of Environmental Health Chinese Center for Disease Control and PreventionBeijingChina Queensland University of Technology BrisbaneAustralia.

On May 5,2023,the World Health Organization(WHO)declared that the coronavirus disease 2019(COVID-19)no longer posed a public Health emergency of international concern(1).As restrictions associated with the epidemic are relaxed and a fresh policy cycle commences,China’s economy is expected to serve as a key driver of global economic postpandemic recovery.

关键词： Health policy relaxed

From concept to action: a united, holistic and One Health approach to respond to the climate change crisis

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Infectious Diseases of Poverty 2022年第1期11卷 68-73页

作者： Renhe Zhang Xu Tang Jian Liu Martin Visbeck Huadong Guo Virginia Murray Catherine Mcgillycuddy Bing Ke Gretchen Kalonji Panmao Zhai Xiaoming Shi Jiahai Lu Xiaonong Zhou Haidong Kan Qunli Han Qian Ye Yong Luo Jianmin Chen Wenjia Cai Huiling Ouyang Riyanti Djalante Alexander Baklanov Lu Ren Guy Brasseur George Fu Gao Lei Zhou Integrated Research on Disaster Risk International Centre of Excellence on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health&Institute of Atmospheric Sciences Fudan UniversityShanghai200438China Science Division United Nations Environment Programme(UNEP)United Nations AvenueGigiriPO Box 30552Nairobi00100Kenya GEOMAR Helmholtz Centre for Ocean Research Kiel and Kiel University KielGermany Key Laboratory of Digital Earth Science Aerospace Information Research InstituteChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences Chinese Academy of SciencesBeijingChina UK Health Security Agency LondonSE18UGUK The Administrative Center for China’s Agenda 21 Ministry of Science and Technology of ChinaBeijing100038China Institute for Disaster Management and Reconstruction Sichuan UniversityChengdu610207China State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing100081China China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijing100021China One Health Center of Excellence for Research and Training School of Public HealthSun Yat-Sen UniversityGuangzhouChina National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)ShanghaiChina Integrated Research On Disaster Risk-IPO BeijingChina State Key Lab of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijing100875China Ministry of Education Key Laboratory for Earth System Modeling and Department of Earth System ScienceTsinghua UniversityBeijingChina ASEAN Secretariat Indonesia Integrated Research on Disaster Risk(IRDR)JakartaIndonesia Science and Innovation Department World Meteorological Organization(WMO)7 bisAvenue de la PaixBP2300CH-1211Geneva 2Switzerland Max Planck Institute for Meteorology HamburgGermany Chinese Center for Dis

It is unequivocal that human influence has warmed the planet,which is seriously affecting the planetary Health including human Health.Adapting climate change should not only be a slogan,but requires a united,holistic action and a paradigm shift from crisis response to an ambitious and integrated approach immediately.Recognizing the urgent needs to tackle the risk connection between climate change and One Health,the four key messages and recommendations that with the intent to guide further research and to promote international cooperation to achieve a more climate-resilient world are provided.

关键词： Climate change One Health International coordination and cooperation Risk-oriented recommendations