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Determination of delta-9-tetrahydrocannabinol content of cannabis seizures in Egypt

Asian Pacific Journal of Tropical Medicine 2017年第3期10卷 291-294页

作者： Ahmed M.A.Souleman Alaa El-Din M.Gaafar Omar M.Abdel-Salam Shaimaa A.ElShebiney Department of Phytochemistry and Plant Systematic National Research CentreCairoEgypt Department of Photochemistry National Research CentreCairoEgypt Department of Toxicology and Narcotics National Research CentreCairoEgypt

Objective:To determine the delta-9-tetrahydrocannabinol(THC)content of cannabis seizures in ***:Unheated and heated extracts of cannabis seizures were prepared from the dried flowering tops and leaves(marijuana)or from the resin(hashish)and subjected to analysis using high performance liquid chromatography(HPLC).Results:The heated resin extract had the peak of THC in a relative ratio of 31.34%,while extracting the resin directly without heating contained only 18.34%of *** the other hand,marijuana showed minimum percentage of THC at 11.188% on heating and 9.55% without ***:These results indicate the high potency of the abused cannabis plant in the illicit Egyptian market.

关键词： Cannabis hashish Marijuana THC High performance liquid chromatography

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Cannabis and Psychosis: A Review of the Risk Factors Involved

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American Journal of Plant Sciences 2020年第12期11卷 1949-1990页

作者： Mohamed Ben Amar Substance Abuse Program Faculty of Continuing Education Université de Montréal Montréal Canada

Abundant literature suggests the hypothesis that cannabis use leads to the onset of psychotic symptoms. However, the nature of the association and the causal link remain controversial. This review aims to identify the risk factors involved in the etiopathogenesis of psychosis or psychotic features. Our electronic search found 1653 studies published until March 1st 2020. Longitudinal studies and literature reviews were selected if they addressed specifically the issues of the cannabis/psychosis relationship and the eventual risk factors involved. Our systematic review identified six potential risk factors involved in the association. They are, in decreasing importance, the dose-response relationship (quantity, frequency and duration of cannabis use), the early age of cannabis consumption, genetic susceptibility, childhood trauma, cigarette smoking and urban environment. In contrast, a significant inverse relationship exists between cannabidiol (CBD) and psychosis: cannabidiol is associated with less psychotic symptoms and manifests antipsychotic properties. Further studies are needed to establish a clear causal relationship between cannabis and psychosis and to identify the qualitative and quantitative contribution of specific risk factors on its onset and sustainability.

关键词： Cannabis Marijuana hashish Psychosis Schizophrenia Risk Factors

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