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慢性乙型肝炎患者健康相关生活质量(hrqol)的评估

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胃肠病学和肝病学杂志 2008年第6期17卷 499-499页

作者：高海女于方浙江大学医学院附属第一医院传染病诊治国家重点实验室浙江杭州310006

健康相关生活质量(health-related quality of life,hrqol)与慢性乙型肝病分期之间的关系是治疗HBV感染需要考虑的重要方面,但目前尚未得到全面的研究.

关键词：慢性乙型肝炎患者健康相关生活质量评估 quality 疾病严重程度 HBV感染 hrqol SF-36

Comparative effects of different types of exercise on health-related quality of life during and after active cancer treatment:A systematic review and network meta-analysis

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Journal of Sport and Health Science 2023年第6期12卷 726-738页

作者： Vicente Martínez-Vizcaíno Iván Cavero-Redondo Sara Reina-Gutiérrez Luis Gracia-Marco JoséJGil-Cosano Bruno Bizzozero-Peroni Fernando Rodriguez-Artalejo Esther Ubago-Guisado Universidad de Castilla-La Mancha Health and Social Research CenterCuenca 16071Spain Facultad de Ciencias de la Salud Universidad Autónoma de ChileTalca 3460000Chile PROFITH(PROmoting FITness and Health through physical activity)Research Group Department of Physical Education and SportsFaculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18012Spain Higher Institute for Physical Education Universidad de la RepúblicaRivera 40000Uruguay Department of Preventive Medicine and Public Health School of MedicineUniversidad Autónoma de MadridMadrid 28029Spain IdiPaz(Instituto de Investigación Sanitaria Hospital Universitario La Paz) Madrid 28029Spain g Epidemiology and Control of Chronic Diseases CIBER of Epidemiology and Public Health(CIBERESP)Madrid 28029Spain Cancer Registry of Granada Escuela Andaluza de Salud PúblicaGranada 18011Spain Cancer Epidemiology Group Instituto de Investigación BiosanitariaGranada 18012Spain

Background The positive influence of most types of exercise has been reported repeatedly,but what the most effective exercise approaches are for improving health-related quality of life(hrqol)in people with cancer remains *** aim of this systematic review and network meta-analysis was to synthesize the evidence from intervention studies to assess the effects of different types of exercise on hrqol during and after cancer *** MEDLINE,SPORTDiscus,the Cochrane Library,Web of Science,and Scopus were searched for randomized controlled trials aimed at testing the effects of exercise interventions meant to improve hrqol in people with *** analyses were conducted for hrqol as measured by general and cancer-specific *** also evaluated whether the effects of exercise were different during and after cancer treatment in both the physical and mental hrqol *** In total,93 studies involving 7435 people with cancer were *** effect size estimates comparing exercise intervention *** care were significant for combined exercise(0.35,95%confidence interval(95%CI):0.14–0.56)for hrqol as measured by general questionnaires,and for combined(0.31,95%CI:0.13–0.48),mind–body exercise(0.54,95%CI:0.18–0.89),and walking(0.39,95%CI:0.04–0.74)for hrqol as measured by cancer-specific *** Exercise programs combining aerobic and resistance training can be recommended to improve hrqol during and after cancer *** scarcity and heterogeneity of these studies prevents us from making recommendations about other exercise modalities due to insufficient evidence.

关键词： Cancer Exercise hrqol Physical activityTagedEnd

老年人运动量与健康相关生活质量的量剂效应——流行病学视角

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成都体育学院学报 2014年第4期40卷 66-72页

作者：李文川上海大学社会学博士后流动站上海200444 中国计量学院江苏杭州310018

目的:探讨老年人运动量与健康相关生活质量(hrqol)的量剂效应。方法:从流行病学视角,运用IPAQ和SF-36量表随机调查了1 006名60-79岁老年人,其中有锻炼习惯794人,对照组212人。结论:①有锻炼习惯老年人hrqol男性为82.55±11.33、女性为81... 详细信息

目的:探讨老年人运动量与健康相关生活质量(hrqol)的量剂效应。方法:从流行病学视角,运用IPAQ和SF-36量表随机调查了1 006名60-79岁老年人,其中有锻炼习惯794人,对照组212人。结论:①有锻炼习惯老年人hrqol男性为82.55±11.33、女性为81.81±11.77,PCS男性为81.61±12.26、女性为81.08±12.87,MCS男性为83.51±12.12、女性为82.87±13.59,与对照组相比有非常显著性差异(Phrqol分值,但两者之间并不是线性关系,中等运动量水平(150-300min/w)与hrqol关联性最强(E2=0.182)。③150-240min/w区间hrqol与周锻炼时间存在量-效益关系,呈线性正相关,锻炼时间>300min/w hrqol呈显著性下降。每次锻炼60min以上、频率3次/周以上hrqol出现显著性升高,运动强度与hrqol未见显著性差异。建议:从hrqol角度分析建议老年人适宜运动运动量为周锻炼时间150-240min,锻炼频率为每周3次以上,每次60-90min,锻炼强度为中等运动强度。

关键词：运动量 hrqol 量剂-效应

3an erectile function be predicted after prostate cancer Ireatment？

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Asian Journal of Andrology 2012年第1期14卷 134-135页

作者： Frances M Alba Run Wang Division of Urology University of Texas Medical School at Houston and Department of Urology University of Texas Medical School at Houston Houston TX 77030 USA University of Texas MD Anderson Cancer Center Houston TX 77030 USA

Prostate cancer （PCa） is the most common solid-organ cancer in American males and the second most common cause of cancer-related death in men. With the advent of prostate-specific antigen screening, death from PCa continues to decline. However, recent evidence suggests that there is now a trend towards increasing incidence.1 Current screening strategies result in increased incidence of low-risk PCa and importantly, the diagnosis of PCa is becoming more common in younger patients.2 The majority of early-stage PCa patients have a high likelihood of disease free survival after treatment.

关键词： Prostate cancer prostate-specific antigen screening radical prostatecomy external beam radiation therapy brachytehrapy hrqol

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Chinese Journal of Cancer Research 2018年第2期30卷 240-253页

作者： Hui Wang Yaqi Pan Chuanhai Guo Fenglei Li Ruiping Xu Mengfei Liu Zhen Liu Fangfang Liu Hong Cai Yang Ke Zhonghu He Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Laboratory of Genetics Peking University Cancer Hospital & Institute Beijing 100142 China Hua County People's Hospital Anyang 456400 China Anyang Cancer Hospital Anyang 455000 China

Objective： There have been few population-based studies evaluating health related quality of life（hrqol） in rural populations in China, and this study aimed to assess the current status of and risk factors for hrqol in a general rural population in high risk region of esophageal cancer in ***： From November 2015 to September 2016, 12,085 permanent residents aged 45–69 years from 257 villages in the Endoscopic Screening for Esophageal Cancer in China（ESECC） trial（Clinical ***：NCT01688908） randomly selected from Hua County, Henan Province, China were interviewed. The EQ-5 D-3 L,a generic measure of hrqol, and a questionnaire were used to assess their hrqol and potential risk ***： Among all the participants, 30.62% of the participants reported problems in at least one EQ-5 D dimension. Pain/discomfort（25.52%） was the most frequently reported problem followed by anxiety/depression（7.97%）, mobility（5.82%）, usual activities（2.61%） and self-care（1%）. These rural residents had a mean EQ-5 D index score of 0.948, and lower EQ-5 D index scores were associated with older age, female gender, lower levels of household annual per capita income, living alone, using shallow wells as main source of drinking water, exposure to family members smoking, testiness, unhealthy dietary habits, overweight or obesity, upper gastrointestinal cancer related symptoms and chronic ***： Rural residents in China have a relatively low quality of life. Health promotion programs in this population should focus on the elderly, especially elderly women and the elderly living alone. Improving basic living circumstances and primary medical care services should be priorities. Results of this study will also serve as the basis for the cost-utility evaluation in our ESECC screening trial.

关键词： hrqol EQ-5D rural population China

Development of otology specific outcome measure:Ear Outcome Survey-16 (EOS-16)

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Journal of Otology 2021年第3期16卷 150-157页

作者： Juha T.Laakso Juha Silvola Timo Hirvonen Samuli Suutarla Ilkka Kivekas Riitta Saarinen Lotta Haavisto Jaakko Laitakari Antti A.Aarnisalo Aarno Dietz Jussi Jero Maija Hytonen Saku T.Sink Department of Otorhinolaryngology-Head and Neck Surgery Head and Neck CenterHelsinki University Hospital and University of HelsinkiHelsinkiFinland Department of Ear Noseand Throat-Division of SurgeryAkershus University HospitalLørenskogNorway Department of Otorhinolaryngology Kymenlaakso Central HospitalKotkaFinland Department of Otorhinolaryngology-Head and Neck Surgery Tampere University Hospital and Tampere UniversityTampereFinland Department of Otorhinolaryngology-Head and Neck Surgery Turku University Hospital and University of TurkuTurkuFinland Department of Otorhinolaryngology-Head and Neck Surgery Oulu University Hospital and PEDEGO Research UnitUniversity of Oulu and Medical Research Center OuluFinland Department of Otorhinolaryngology-Head and Neck Surgery Kuopio University Hospital and University of KuopioKuopioFinland

Purpose An important outcome measure of patient care is the impact on the patient’s health-related quality of life(hrqol).Current ear-specific hrqol instruments are designed for one diagnosis and emphasize different subdivisions such as symptoms,hearing problems,psychosocial impact,and the need for *** optimal length of the recall period has not been *** these reasons,a new survey is needed that would cover most chronic ear *** A preliminary 24-item survey(EOS-24)was *** adult patients(included n=186)with one of seven different chronic otologic conditions from all university hospitals in Finland were recruited to respond to EOS-24 and the 15D general hrqol *** recruiting otologists evaluated the severity of the disease and the disability caused by it.A control group was *** on the patients’responses in different diagnosis groups,the items were reduced according to pre-defined *** resulting survey was validated using a thorough statistical *** The relevance and necessity of the original 24 items were thoroughly investigated,leading to the exclusion of 8 items and the modification of *** remaining 16 items were well-balanced between subdivisions and were useful in all seven diagnosis groups,thus constituting the final instrument,*** most suitable recall period was three *** EOS-16 has been created according to the hrqol survey guidelines with a versatile nationwide patient *** survey has been validated and can be used for a wide range of chronic ear diseases as a hrqol instrument.

关键词： Otology Chronic ear diseases hrqol Health-related quality of life PROM

Depression and health-related quality of life of patients with type 2 diabetes attending tertiary level hospitals in Dhaka,Bangladesh

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Global Health Research and Policy 2023年第1期8卷 91-104页

作者： Manish K.Namdeo Sarita Verma Rajat Das Gupta Rubana Islam Shaila Nazneen Lal B.Rawal Independent Scholar and Alumni JPGSPHBRAC UniversityBangladeshChhindwaraIndia Tata Institute of Social Sciences MumbaiIndia University of South Carolina ColumbiaSCUSA International Initiative for Impact Evaluation(3Ie) ColumbiaSCUSA University of Texas at El Paso El PasoTXUSA Central Queensland University Sydney CampusSydneyAustralia.

Introduction Type 2 diabetes mellitus(T2DM)and depression are closely *** with T2DM are at increased risk of developing depression and vice versa.T2DM and depression comorbid conditions adversely affect Health-Related Quality of Life(hrqol)and management of *** this study,we assessed depression and hrqol among patients with T2DM in Dhaka,*** A cross-sectional study was conducted in two tertiary-level hospitals in Dhaka,*** were collected from 318 patients with T2DM.A set of standard tools,PHQ-9(for assessing depression)and EuroQol-5D-5L(for assessing the hrqol),were *** analyses,including Chi-square and Fisher’s exact tests,Wilcoxon(Mann-Whitney),and Spearman’s correlation coefficient tests,were performed using SPSS(v.20).Results The majority of the patients(58%)were females,with a mean age(standard deviation)of 52±10 years,and 74%of patients lived in urban *** prevalence of depression was 62%(PHQ-9 score≥5).Over three-quarters(76%)reported problems in the anxiety/depression dimension of EQ-5D,followed by pain/discomfort(74%),mobility(40%),self-care(36%),and usual activities(33%).The depression and T2DM comorbid condition were associated with all the five dimensions of EQ-5D(χ^(2)statistics with df=1 was 52.33,51.13,52.67,21.61,7.92 for mobility,self-care,usual activities,pain/discomfort,and anxiety/depression dimensions respectively,p-hrqol was negatively affected by comorbid depression in T2DM *** suggests the importance of timely screening,diagnosis,treatment,and follow-up of comorbid depression in T2DM patients to improve overall health and QOL.

关键词： Depression hrqol Comorbidity Bangladesh Type 2 diabetes

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肠易激综合征对健康相关生活质量的影响

世界核心医学期刊文摘（胃肠病学分册） 2006年第9期2卷 30-31页

作者： Amouretti M. Gaudin A.-F. 张诗峰 Hpital du Haut Lévêque Service de Gastroentérologie5avenue Magellan33604 Pessac

Aims-To assess the impact of irritable bowel syndrome(IBS)on patient-reported health-related quality of life(hrqol).Methods-Two hrqol instruments were administered by telephone interviews to a sample of 253 IBS French patients recruited from the general *** was diagnosed according to the Manning,Rome I and Rome II *** with organic diseases were excluded from the study.A generic instrument,the Short Form 36(SF-36),and an IBS disease-specific instrument,the IBSQOL,were ***-Patients with IBS had statistically significant(P hrqol on both the SF-36 and the IBSQOL scores than men(N = 61)for all domains except energy on the SF-36 and the sleep on the *** deteriorated with time since onset of IBS symptoms for some domains such as *** both instruments,a positive correlation was observed between low scores and intensity of pain and *** patients with a predominance of diarrhea(N = 72)exhibited significantly greater impairment of hrqol in the emotional domain than IBS persons with constipation predominance(N = 65)(P≤0.05).Conclusion-IBS has a significant impact on hrqol of *** addition,specific characteristics such as gender,symptom severity and time since onset of symptoms are predictive of more impaired health-related quality of life.

关键词：健康相关生活质量肠易激综合征 IBS患者 hrqol SF-36 量表评估普通人群 Rome

Correlates and Predictors of Health-Related Quality of Life among Patients with COPD: An Integrative Review

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Open Journal of Nursing 2019年第12期9卷 1203-1225页

作者： Nazih Abu Tabar Jafar Alasad Alshraideh School of Nursing The University of Jordan Amman Jordan Nursing Department Ministry of Health Amman Jordan

Background: Health-related quality of life is an important outcome variable with COPD patients. Impaired health-related quality of life among COPD patients is closely related to various factors. There are many factors that predict the hrqol and the correlation with other important variables. Predictors of health-related quality of life were debatable in the literature. Aim: This review aimed to describe the correlation with hrqol and to explore the predictors of hrqol among patients with COPD. Methods: An integrative review method was conducted. A search protocol was conducted using EBSCO, Pubmed, CINAHL, Ovid, ProQuest, Cochrane, and Google Scholar databases up to October 1, 2019. Results: The review results out of 30 articles that discuss the predictors of hrqol and 22 articles that discuss the hrqol correlations with other important variables. The hrqol predictors are classified according to sociodemographic factors and clinical factors, and also, the correlation and prediction of hrqol with anxiety, fatigue, and uncertainty. The results of this review showed controversies in predictors between the studies. The most retrieved predictors were age, educational level, comorbidities, socioeconomic status, FEV1% predicted, GOLD stages, and the number of hospitalizations. The variables of anxiety and fatigue were strongly correlated and predicted hrqol. While uncertainty was not reported as a significant hrqol predictor. Conclusion: This review provides support about reliable predictors than unreliable one although some predictors still need further research in different races and cultures. Future research is needed to explore whether uncertainty can predict hrqol among patients with COPD.

关键词： hrqol COPD Integrative Review Uncertainty Anxiety Fatigue