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Prevalence and Predictors of Anxiety and Depression among gynaecological cancer Patients at a Tertiary Health Facility in Southern Nigeria

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Journal of Biosciences and Medicines 2023年第7期11卷 96-111页

作者： Justina Omoikhefe Alegbeleye Olusegun Biyi-Olutunde Department of Obstetrics and Gynaecology University of Port Harcourt Teaching Hospital Port Harcourt Nigeria Department of Radiation and Clinical Oncology University of Port Harcourt Teaching Hospital Port Harcourt Nigeria

Background: cancer patients frequently suffer from mental health problems because of their reactions to their cancer diagnosis, cancer type, treatment effects, recurrence, fear of the end-of-life, survival, and financial burden. Some hospitals have integrated mental health assessments into cancer care, but our centre has little experience with this practice. Aim and Objectives: To ascertain the prevalence and predictors of anxiety and depression in patients with gynaecological cancer at a tertiary health facility in southern Nigeria. Materials and Methods: This was a facility-based cross-sectional descriptive study of 75 women with histologically confirmed gynaecological cancer managed at the University of Port Harcourt Teaching Hospital, Port Harcourt, from January 1, 2022, to December 31, 2022. Individuals having a history of drug addiction, severe cognitive impairment, non-consenting patients, and those with communication difficulties were excluded from the study. A data collection form was used to obtain socio-demographic, reproductive, and clinical characteristics, while the Hospital Anxiety and Depression Scale (HADS) was used to assess for anxiety and depression. Data was analyzed using descriptive statistics to determine the association of variables with anxiety and depression. Results: Most 27 (36.0%) of the respondents were in 40 - 49 age group with a mean age of 50.4 ± 12.3 years. The study showed that 39 (52.0%) of the respondents exhibited symptoms of anxiety, of which 14 (35.9%) were mild, 20 (51.3%) had moderate anxiety and 5 (12.8%) experienced severe anxiety. In addition, 46 (61.3%) of them showed symptoms of depression, of which 17 (37.0%) were mild, 15 (32.6%) were moderate and 14 (30.4%) experienced severe depression. The ratio of respondents who showed anxiety to those that showed symptoms of depression was 5: 6. The factors associated with anxiety were partner’s educational level (X2 = 4.745, p = 0.029), parity (X2 = 6.651

关键词： Prevalence Predictors Anxiety Depression gynaecological cancer

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Burden of gynaecological cancers in developing countries

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World Journal of Obstetrics and Gynecology 2013年第1期2卷 1-7页

作者： Chukwuemeka Anthony Iyoke George Onyemaechi Ugwu Department of Obstetrics and Gynaecology University Hospital of Wales Heath Park Cardiff CF14 4XN United Kingdom Department of Obstetrics and Gynaecology University of Nigeria Teaching Hospital Ituku-Ozalla Enugu 4000001 Nigeria

Approximately 1：4 of all cancers in women in develop-ing countries （excluding non-melanoma skin cancer） is a gynaecological cancer. The gynaecological cancer burden in developing countries is huge primarily due to the high incidence and mortality of cervical cancer. Cervical cancer accounts for over 60% of the gynaeco-logical cancer burden in developing countries despite being preventable by current technologies. This is due to the absence of effective nationally organized screening programmes in most developing countries. Institution of such programmes, therefore, has the potential to dramatically reduce gynaecological cancer burden in these countries. Subsidized human papil-loma virus （HPV） vaccine and HPV typing as well as cheap screening techniques such as visual inspection aided with acetic acid hold the key to effective preven-tion of cervical cancer in these countries. This is be-cause a signifcant proportion of patients in developing countries are unable to access and avail themselves of the few available preventive, diagnostic and treatment services because of poverty. Although, advocacy and the political will to invest in the development of human resources and healthcare infrastructure appear criti-cal to gynaecological cancer control and reducing the burden of disease in many developing countries, the proposition assumes that resources are truly available for this investment. This may not be true. Many devel-oping countries rely on foreign aids for developmental programmes and these aids have dwindled signifcantly with the current global economic meltdown.

关键词： gynaecological cancer cancer burden Can-cer mortality cancer morbidity cancer prevention

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Evolution of radical hysterectomy for cervical cancer along the last two decades: single institution experience

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Chinese Journal of cancer Research 2016年第2期28卷 215-220页

作者： Claudia Arispe Ana Isabel Pomares Javier De Santiago Ignacio Zapardiel Gynecologic Oncology Department La Paz University Hospital

Background： The radical hysterectomy （RH） surgical technique has improved along the years. It is used for the treatment of cervical cancer, endometrial cancer when affecting the cervix, and upper vaginal carcinomas. Our aim was to describe the historical evolution of the technique after the introduction of laparoseopy at our institution. Methods： We performed a retrospective review of medical records of patients who underwent RH, grouped in three periods according to the year of surgery： 1990-1999, 2000-2009 and 2010-2013. Patients＇ characteristics, pathologic details, intraoperative and postoperative complications were analyzed and comoared throughout the time periods. Results： A total of 102 cases of RH were performed at our center during the study period. Among all data collected, the presence of necrosis, age, number of lymph nodes, surgery route, operating time, hospital stay, blood loss and transfusion requirement were statistically significant different among groups. Conversion to laparotomy rate was 19% for the second period compared to the absence of cases in the last one. No significant differences （P=0.124） were observed in the adjuvant treatment received among the three different groups. At the time of the last contact the patients free of disease were 12 （85.7%）, 53 （91.3%） and 26 （86.6%） respectively （P=0.406）. Regarding the disease-free interval, we found significant better outcomes in the group of laparotomy compared to laparoscopy （P=0.015）.Conclusions： Laparoscopic RH is an acceptable surgery with advantages like magnified vision of the operation＇s field, lower surgical complications, shorter hospital stay and earlier resumption to daily activities.

关键词： gynaecological cancer radical hysterectomy (RH) laparoscopy cervical cancer

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cancer in Women and Its Relation to Work Systematic Review

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Occupational Diseases and Environmental Medicine 2021年第2期9卷 74-91页

作者： Maria Teófila Vicente-Herrero Maria Victoria Ramírez-Iñiguez de la Torre Luisa Capdevila García Asociacion Españ ola de Especialistas en Medicina del Trabajo Occupational Health and Safety Services of SPP CorreosValencia Spain Asociacion Españ ola de Especialistas en Medicina del Trabajo Occupational Health and Safety Services of SPP Correos andOccupational Health and Safety Services of SPA ITEM-Prevencion Albacete Spain Asociacion Españ ola de Especialistas en Medicina del Trabajo Occupational Health and Safety Services of SPM MAPFREValencia Spain

Nowadays, cancer is one of the main worldwide causes of death and an increasing issue in public health. In the European Union, it is the first work-related cause of death. Studies about occupational risk exposure are a useful field of investigation to determine cancerous elements;special attention is paid to the relationship between cancer and work in women, who must constantly adapt to the working market and the new working fields, with their diverse degrees of exposure to risks. This revision has reviewed the bibliography gathered in Medline related to breast cancer, cervix cancer, uterus cancer, and ovarian cancer, along with their relationship with different work-related risks and types of working roles. The results have shown enough scientific evidence to suspect that work related exposition could be a plausible cause of these gynaecological cancers. Therefore, we want to stress the need of enhancing the coordinated investigation between all the medical specialties involved, and to encourage the spread of the necessary knowledge to manage and prevent them.

关键词： gynaecological cancer Breast cancer Work-Related Risk Factors Workplace Occupational Health

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Spontaneous Regression of Clear Cell Carcinoma of the Endometrium

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Journal of cancer Therapy 2016年第9期7卷 635-645页

作者： Ketevani Kankava Alexi Baidoshvili Eltjo Schutter Sytske Van der Meer David Makaridze Department of Pathology N. Kipshidze Central University Clinic Tbilisi Georgia Department of Pathology Laboratory of Pathology Oost Nederland Hengelo The Netherlands Department of Obstetrics & Gynaecology Medisch Spectrum Twente Enschede The Netherlands Department of Psychiatry Mediant Locatie Helmerzijde Enschede The Netherlands

This report documents a rare case of complete spontaneous regression of clear cell carcinoma of the endometrium. An elderly woman with paranoid schizophrenia was admitted to the hospital because of vaginal bleeding. Diagnostic curetting and biopsy were performed and she was diagnosed with clear cell carcinoma of endometrium. Anti-tumour therapy was not possible because of her poor psychiatric status. 13 months later the woman died of a natural cause and at autopsy the endometrial tumour could no longer be identified. Myocardial infarction, aggravated by poor functional status of organism due to sepsis, was concluded to be the cause of death.

关键词： gynaecological cancer Pathology Spontaneous Regression Clear Cell Carcinoma Endometrial cancer Glucose Metabolism

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