检索结果-南通市图书馆

Antidiarrheal and protein conservative activities of Psidium guajava in diarrheal rats

Journal of Integrative Medicine 2019年第1期17卷 57-65页

作者： Khaled M.M.Koriem Mahmoud S.Arbidb Hend N.Saleh Department of Medical Physiology National Research Centre Department of Pharmacology National Research Centre Faculty of Pharmacy Cairo University

Objective: Psidium guajava occurs worldwide in tropical and subtropical areas. It has been used to treat inflammation, diabetes, fever, hypertension and ulcers. However, its antidiarrheal and protein conservative activities still need to be ***: Fifty-four male rats were divided into normal and diarrheal rats. The normal rats were divided into 4 groups: control, low-dose P. guajava leaf extract(50 mg/kg), high-dose P. guajava leaf extract(100 mg/kg) and gallic acid. Treatments were administrated orally in 1 mL saline for a 1-month *** diarrheal rats were divided into 5 groups: desmopressin(0.2 mg/kg) drug, low-dose P. guajava leaf extract(50 mg/kg), high-dose P. guajava leaf extract(100 mg/kg), gallic acid and an untreated *** were given daily for a 1-month period while the untreated control received no ***: Diarrhea was responsible for an observed decline in kidney weight and serum sodium, potassium and chloride. Further, diarrhea was positively correlated with a significant increase in urine volume, and excretion of electrolytes, serum urea, creatinine and uric acid in the urine. In contrast, there was a proportional increase in the lipid peroxidation value in diarrhea and a significant decline was observed in serum superoxide dismutase, glutathione peroxidase and glutathione levels in diarrhea. Also, diarrhea inhibited blood proteins. The oral intake of P. guajava leaf extract by diarrheal rats restored all of these parameters to near normal levels. High-dose P. guajava leaf extract was more effective than the same compound at a low ***: P. guajava leaf extract elicited antidiarrheal and protein conservative effects.

关键词： Psidium guajava Myrtaceae Diarrhea Proteins Antioxidant

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Anticancer effect of Psidium guajava(Guava) leaf extracts against colorectal cancer through inhibition of angiogenesis

引用

Asian Pacific Journal of Tropical Biomedicine 2020年第7期10卷 293-307页

作者： Bronwyn Lok Doblin Sandai Hussein M.Baharetha Mansoureh Nazari V Muhammad Asif Chu Shan Tan AMS Abdul Majid EMAN Laboratory Discipline of PharmacologySchool of Pharmaceutical SciencesUniversiti Sains MalaysiaPenangMalaysia Infectomics Cluster Advance Medical and Dental InstituteUniversiti Sains MalaysiaPenangMalaysia Department of Pharmacy College of Medicine and Health SciencesHadhramout UniversityHadhramoutYemen Department of Pharmacology Faculty of Pharmaceutical SciencesGovernment College University FaisalabadFaisalabadPakistan Discipline of Pharmacology School of Pharmaceutical SciencesUniversiti Sains MalaysiaPenangMalaysia ACRF Department of Cancer Biology and Therapeutics John Curtin School of Medical ResearchAustralian National UniversityCanberraAustralia

Objective:To evaluate the anti-angiogenic and anticancer activities of Psidium guajava leaf extracts against angiogenesis-dependent colorectal ***:Three extracts were produced using distilled water,ethanol,and n-hexane as *** extracts were physically characterised through gas chromatography–mass spectrometry,ultraviolet–visible spectroscopy,and Fourier transform infrared *** antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl,total phenolic content,and total flavonoid content *** assess their anti-angiogenic activity,cell viability and rat aortic ring assays were conducted,while cell migration,tube formation,colony formation,and VEGF ELISA assays were conducted to elucidate their effects on different aspects of *** docking was used to assess the antiangiogenic potential of some possible compounds in the *** spheroid assay was used to assess the extracts’potential as a treatment for colorectal ***:The ethanol extract showed the best antioxidant *** distilled water and ethanol extracts exhibited more inhibitory activity against ***926 cell viability and aortic ring microvessel *** addition,the ethanol extract performed significantly better than the distilled water extract against cell migration and colony formation,and VEGF expression of the cells was suppressed by the ethanol *** the distilled water and ethanol extracts showed significant inhibitory effect on ***926 tube formation and tumour spheroids consisting of ***926 and HCT116 *** ethanol extract containedβ-caryophyllene andβ-elemene by phytochemical analysis and subsequent docking studies,which may contribute to its anti-angiogenic ***:The ethanol extract of Psidium guajava has potential in the treatment of colorectal cancer through the inhibition of angiogenesis.

关键词： Angiogenesis Antioxidant Colorectal cancer Psidium guajava VEGF

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antidiabetic and antidiarrhoeal effects on ethanolic extract of Psidium guajava(L.) *** in Wister rats

引用

Asian Pacific Journal of Tropical Biomedicine 2015年第1期5卷 10-14页

作者： Santosh Mazumdar Rashcda Akter Debashish Talukder Pharmacology research division Bangladesh Council of Scientific and Industrial Research Laboratories Chittagong Applied Zoology Research Division Bangladesh Council of Scientific and Industrial Research Laboratories Rajshahi

Objective:To evaluate the antidiabetic and the antidiarrhoeal effects of ethanolic extracts of Psidium guajava leave(EEPGL) in Wisier rais to support its traditional ***:Oral glucose tolerance test model and alloxan induced diabetic test model were performed to evaluate antidiabetic activity of EEPGL at doses of 1.***.0.50 and 0.75 g/kg *** antidiarrhoeal effects of *** oil-induced diarrhoea model and gastrointestinal motility test with barium sulphate milk model were also assessed at doses of750.500 and 250 mg/***:Administration of EEPGL at doses 1.00 and 0.50 g/kg significantly(Pguajava leave in Wister rats.

关键词： Psidium guajava Leave extract Antidiabetic Antidiarrhoea Wister rats

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Therapeutic Effects of Essential Oil from Waste Leaves of Psidium guajavaL. against Cosmetic Embarrassment Using Phylogenetic Approach

引用

American Journal of Plant Sciences 2012年第6期3卷 745-752页

作者： Ahsan Kamran Rohit Mishra Rita Gupta Awadhesh Kumar Ashok Bajaj Anupam Dikshit Biological Product Laboratory Department of Botany University of Allahabad Allahabad India Department of Dermatology and Veneral Diseases M.L.N.Medical College Allahabad India. Department of Horticulture Aromatic & Medicinal Plants Mizoram University Aizawl India

Medicinal plants are facing threats due to loss of habitat and overexploitation of knows species. Therefore the present work shows utilization of essential oil from discarded leaves of Psidium guajava Linn. against human dermatophytic fungi Trichophyton rubrum, T. mentagrophytes, Trichophyton violaceum, Trichophyton tonsurans, Epidermophyton floccosum, Microsporum gypseum and Microsporum canis. The oil was found to be fungicidal at 3.0 μl/ml and it tolerated heavy inoculum of pathogens at fungicidal concentrations. The fungicidal activity of the oil was thermostable, up to 70°C and shelf life was found to be six months, which was maximum the time taken into consideration. The oil having cineole, caryophyllane, copaene, azulene and eucalyptol as main constituents, exhibited broad fungicidal activity. The oil did not show any adverse effect on mammalian skin upto 5% concentration. Phylogeny of the dermatophytes with respect to toxicity of the oil has also been discussed using molecular data. The cost effective formulation from waste leaves can be exploited after undergoing double blind successful multicentral topical testing.

关键词： Essential Oil Dermatophytes Phylogeny Discarded Leaves Psidium guajava L. Trichophyton rubrum T. mentagrophyte

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antibacterial Activity of Psidium guajavaLeaf Extract against Selected Pathogenic Bacteria

引用

Advances in Microbiology 2019年第12期9卷 1012-1022页

作者： Anayochukwu Chibuike Ngene John C. Aguiyi Chinedu Joshua Chibuike Virginia O. Ifeanyi Kelechi M. Ukaegbu-Obi Esther Garos Kim Uchechukwu C. Ohaeri Bruno O. Onyemegbulem Africa Center of Excellence in Phytomedicine Research and Development University of Jos Jos Plateau State Nigeria Department of Microbiology College of Natural Sciences Michael Okpara University of Agriculture Umudike Abia State Nigeria Department of Medical Microbiology Faculty of Clinical Sciences College of Health Sciences University of Jos Jos Plateau State Nigeria

This study has been embarked upon due to increased resistance of bacteria to many already synthesized drugs and the high price of the orthodox medicines in the market, the antimicrobial effect of Psidium guajava leaf extracts against selected drug-resistant bacteria will help to reduce the overdependence on orthodox or synthetic drugs which greater population of the society cannot afford due to economic/financial restriction. Ethanolic and aqueous extracts of Psidium guajava were assayed for antibacterial activity using the agar dilution method in the determination of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The bioactive components of the extracts were determined using standard techniques and the inhibitory activities of the extracts were compared to gentamicin, ciprofloxacin, erythromycin, azithromycin, ofloxacin, and nitrofurantoin. The MIC of the extract on the test organisms ranges from 10 mg/ml - 40 mg/ml. The sensitivity test showed that the organisms were susceptible to Psidium guajava leave extract except Pseudomonas aeruginosa. The phytochemical analysis of the extracts revealed the presence of bioactive compounds such as Tannin, Saponin, Balsam, Flavonoids, Alkaloids, Cardiac glycosides, Carbohydrate, Resins, Terpenes, and Sterols. It has been shown that the leaves of Psidium guajava have antibacterial effects and hence can be used to treat the ailments caused by those organisms at a particular dosage and concentration. However, more research work on its toxicity level, synergistic or antagonistic interaction with other plants or drugs is needed to consolidate its usage.

关键词： Antibiotic Resistance Psidium guajava Minimum Inhibitory Concentration Minimum Bactericidal Concentration Zone of Inhibition Phytochemical Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatoprotective Effect of Guava (Psidium guajavaL.) Leaf Extracts on Ethanol-Induced Injury on Clone 9 Rat Liver Cells

引用

Food and Nutrition Sciences 2011年第9期2卷 983-988页

作者： Hung-Hui Chen Po-Hua Wu Diana Lo Yun-Chieh Pan Ming-Chang Wu Department of Food Science National Pingtung University of Science and Technology Department of Microbiology Immunology and Biophamarceuticals National Chiayi University Department of Tropical Agriculture and International Cooperation National Ping

Guava (Psidium guajava L.), a tropical fruit, belongs to Myrtaceae family. Leaves and fruits of guava have been reported to have an anti-diarrheal, hypoglycemic, lipid lowering, anti-bacterial in addition to antioxidant activities. The aim of this study was to investigate several guava leaf extract cytotoxic effects on healthy clone 9 liver cells and its hepatoprotective effects on ethanol-induced heap-toxicity. It was discovered that when the clone 9 liver cells were treated with guava (Psidium guajava Linn.) extracts for 24 hours, there was no retardation of growth as well as when ethanol and acetone extracts at low concentrations 100 μg/mL and 50 μg/mL were administered however cytototoxic effects were detected at higher concentrations. Water and hot water extracts in concentrations lower than or equal to 500 μg/mL revealed no cytotoxic effects. Injury induction to healthy clone 9 liver cells using 5% alcohol concentration for 30 minutes revealed the hepatoprotective properties of guava (Psidium guajava Linn.) extracts. This was significant in concentrations of 100 μg/mL or lower for ethanol and all concentrations for hot water extracts. Hot water extracts showed higher hepatoprotective and lower cytotoxic properties than other extracts.

关键词： Guava (Psidium guajava Linn.) Alcohol-Injured Cell Hepatoprotective Properties Clone 9 Cell Cytotoxicity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biogenic Synthesis of Silver Nanoparticles Using Guava (Psidium guajava) Leaf Extract and Its Larvicidal Action against Anopheles gambiae

引用

Journal of Biomaterials and Nanobiotechnology 2020年第1期11卷 49-66页

作者： Agnes Antoinette Ntoumba Francois Eya’ane Meva Wolfgang Eyisap Ekoko Loick Pradel Kojom Foko Etoile Ngo Hondt Carsten Schlüsener Bastian Moll Gisele Etame Loe Philippe Belle Ebanda Kedi Jean Yves Sikapi Fouda Christoph Janiak Leopold Gustave Lehman Department of Animal Biology and Physiology Faculty of Science The University of Douala Douala Cameroon Department of Pharmaceutical Sciences Faculty of Medicine and Pharmaceutical Sciences The University of Douala Douala Cameroon Institute for Inorganic Chemistry and Structural Chemistry Heinrich-Heine-University Düsseldorf Universitätsstr 1 Düsseldorf Germany Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC) Yaoundé Cameroon

The progress in the field of nanotechnology has contributed to the development of tools for combating the most critical problems in developing countries. The requirements that such tools should meet are low-cost and resource settings, environmental protection, ease of use, and availability. The use of plant properties for the generation of nanoparticles (NPs), which serve as bioinsecticides to combat the plasticity and resistance of mosquitoes and parasites, is considered possible. Here, we report for the first time the larvicidal activity of silver (Ag) NPs (AgNPs) synthesized from Psidium guajava (P. guajava) extract, which targets the 4th instar larvae of Anopheles gambiae. Concentrations of AgNPs between 0 and 200 ppm were used and their LC50 at 24 h and 48 h were determined as 19.55 ppm and 8.737 ppm, respectively. The AgNPs were stable and highly effective against the larvae of A. gambiae and thereby we anticipate that they can be used to combat vector-borne diseases in developing countries.

关键词： Vector Control Anopheles gambiae Silver Nanoparticles Psidium guajava

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antibacterial activities of ethanol extracts of Philippine medicinal plants against multidrug-resistant bacteria

引用

Asian Pacific Journal of Tropical Biomedicine 2015年第7期5卷 525-532页

作者： Demetrio L.Valle Jr. Jeannie I.Andrade Juliana Janet M.Puzon Esperanza C.Cabrera Windell L.Rivera Institute of Biology College of Science University of the Philippines Makati Medical Center Natural Sciences Research Institute University of the Philippines Biology Department De La Salle University

Objective: To investigate the antibacterial activities of crude ethanol extracts of 12 Philippine medicinal ***: Crude ethanol extracts from 12 Philippine medicinal plants were evaluated for their antibacterial activity against methicillin-resistant Staphylococcus aureus, vancomycinresistant Enterococcus, extended spectrum β-lactamase-producing, carbapenem-resistant Enterobacteriaceae and metallo-β-lactamase-producing Pseudomonas aeruginosa and Acinetobacter baumannii. Results: The leaf extracts of Psidium guajava, Phyllanthus niruri, Ehretia microphylla and Piper betle(P. betle) showed antibacterial activity against the Gram-positive methicillinresistant Staphylococcus aureus and vancomycin-resistant Enterococcus. P. betle showed the highest antibacterial activity for these bacteria in the disk diffusion(16-33 mm inhibition diameter), minimum inhibitory concentration(19-156 μg/m L) and minimum bactericidal concentration(312 μg/m L) assays. P. betle leaf extracts only showed remarkable antibacterial activity for all the Gram-negative multidrug-resistant bacteria(extended spectrum β-lactamaseproducing, carbapenem-resistant Enterobacteriaceae and metallo-β-lactamase-producing) in the disk diffusion(17-21 mm inhibition diameter), minimum inhibitory concentration(312-625 μg/m L) and minimum bactericidal concentration(312-625 μg/m L) assays. Conclusions: P. betle had the greatest potential value against both Gram-negative and Grampositive multidrug-resistant bacteria. Favorable antagonistic activities were also exhibited by the ethanol extracts of Psidium guajava, Phyllanthus niruri and Ehretia microphylla.

关键词： Philippine herbal medicine Multidrug-resistant bacteria Piper betle Psidium guajava Phyllanthus niruri Ehretia microphylla

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

番石榴果实药学研究概况

引用

安徽农业科学 2013年第17期41卷 7460-7462页

作者：刘纯每乐李鑫杨红超熊本涛陈丹巩江倪士峰西北大学外国语学院陕西西安710069 西北大学生命科学学院陕西西安710069 西藏民族学院医学院陕西咸阳712082

在广泛文献检索基础上,对番石榴果实的成分、药理及临床应用等研究进展进行概述,为深入开发利用提供科学资料。

关键词：番石榴(Psidium guajava L ) 果实成分药理临床应用

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

紫外分光光度法测定番石榴叶总三萜含量

引用

海峡药学 2014年第4期26卷 55-57页

作者：黄桂坤邱莉刘向红黄丽凤李福森罗艳谢集照张若蘅广西医科大学药学院南宁530021

目的：建立一种番石榴叶药材中总三萜含量测定的方法，并考察10批番石榴叶药材中总三萜含量。方法以熊果酸为对照品，香草醛-冰醋酸-高氯酸为显色体系，采用紫外分光光度法在最大吸收波长为548nm处测定番石榴叶药材总三萜含量。结果熊... 详细信息

目的：建立一种番石榴叶药材中总三萜含量测定的方法，并考察10批番石榴叶药材中总三萜含量。方法以熊果酸为对照品，香草醛-冰醋酸-高氯酸为显色体系，采用紫外分光光度法在最大吸收波长为548nm处测定番石榴叶药材总三萜含量。结果熊果酸在8.13～28.44μg · mL^ -1范围内线性关系良好，总三萜平均回收率为99.43％，RSD为2.30％。结论该方法操作简便、快速、准确、稳定可靠，可作为番石榴叶药材总三萜含量测定的方法。

关键词：番石榴叶总三萜紫外分光光度法 Psidium guajava L

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：