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Systemic Sarcoidosis Revealed by a Nasal Lesion: A Case Report

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International Journal of Clinical Medicine 2015年第4期6卷 257-261页

作者： Madiha Mahfoudhi Khaled Khammassi Sami Turki Mamia Ben Salah Department of Internal Medicine A Charles Nicolle Hospital Tunis Tunisia Department of Oto-Rhino-Laryngology Charles Nicolle Hospital Tunis Tunisia

A 62-year-old man presented with bilateral nasal obstruction and recurrent epistaxis episodes. Physical examination revealed normal body temperature and free cervical lymph nodes areas. Nasal endoscopy found a congestive nasal mucosa associated to bilateral inferior turbinate hypertrophy with a granular aspect of the right inferior turbinate. The biological examination showed lymphopenia, inflammatory syndrome, high serum level of angiotensin-converting enzyme and β2 microglobulin. Tuberculin skin test and Quantiferon gold were negative. The nasal and accessory salivary gland biopsies revealed granulomatous giant cell lesions non-caseating evoking systemic sarcoidosis. Ziehl-Neelsen staining and Lowenstein culture were negative. The diagnosis was systemic sarcoidosis revealed by nasal localization. The systemic extension research was negative. The treatment was based on corticosteroids (1 mg/kg/day) and gradual degression doses associated to a local nasal corticosteroid. The outcome was favorable with improvement of nasal obstruction and disappearance of initial lesions. The follow-up was 2 years.

关键词： Sarcoidosis Nose granuloma Corticosteroids

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INFECTIOUS DISEASE

China Medical Abstracts(Internal Medicine) 1994年第3期11卷 133-136页

Preliminary Experimental Study on Anti-inflammatory Effect of Extract from Excoecaria cochinchinensis *** a National Medicine

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Medicinal Plant 2020年第1期11卷 29-31页

作者： Jiangcun WEI Silu HE Haisheng ZENG Dongmei HUANG Chengtong LIU Qiji ZHOU Honghan QIN Guangxi International Zhuang Medical Hospital Nanning 530201China The First Affiliated Hospital of Youjiang Medical University for Nationalities Baise 533000China

[Objectives]To study the anti-inflammatory effects of water extract and ethanol extract from Excoecaria cochinchinensis Lour.[Methods]The acute and chronic inflammation models of mouse paw edema induced by cotton ball granuloma and carrageenan were established respectively,and the anti-inflammatory effects of water and ethanol extract from *** *** acute and chronic inflammation in mice were *** experimental mice were equally divided into three groups of high,medium and low dose of *** Lour.(60,40 and 20 g/kg),dexamethasone(0.006 g/kg)group and blank group(distilled water).In the cotton ball granuloma test in mice,the mice were given intragastric administration continuously for 7 d after cotton ball *** the experiment of inflammation induced by carrageenan,the mice in each group were given intragastric administration once a day for 7 d,and the inflammatory model was made after the last administration.[Results]The granuloma inhibition rates of mice in the high,medium and low dose groups of water extract and ethanol extract from *** Lour were significantly lower than those in the blank group(P<0.05).The degree of paw edema in each dose group of water and ethanol extract from *** *** significantly lower than that in the blank group(P<0.05).[Conclusions]The water and ethanol extracts from *** *** significant anti-inflammatory effects.

关键词： Excoecaria cochinchinensis Lour. Extract Anti-inflammation Cotton ball granuloma Paw edema

Clinicopathologic Correlation: Firm Mass on the Lateral Aspect of the Posterior Maxilla

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Open Journal of Stomatology 2014年第4期4卷 179-183页

作者： Darin T. Johnston James J. Closmann Pallavi Parashar Thomas J. Borris Oral and Maxillofacial Surgery University of Colorado School of Dental Medicine Aurora USA

We present the case of a 45-year-old Hispanic female with a slowly enlarging mass on her left maxilla in the region of teeth #15 and #16. A differential diagnosis is presented along with the histologic findings and tr... 详细信息

关键词： Exostosis Gingival Diseases Oral Pathology Pyogenic granuloma Surgery

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肱骨嗜酸性肉芽肿病例报告1例并文献回顾

重庆医学 2017年第26期46卷 3738-3739页

作者：王鹏余海波禤天航刘礼初广州中医药大学研究生院广州510405 广东省佛山市中医院骨关节科 528000 广东省佛山市中医院骨研究所 528000

骨嗜酸性肉芽肿（eosinophilic granuloma of bone,EGB）是一种发生于骨组织的良性肿瘤性疾病,该病的病理改变主要包括局部组织细胞增生和嗜酸性细胞的浸润,好发于青少年。EGB的发病率极低,临床表现和影像学表现无明显特异性,容易被误... 详细信息

骨嗜酸性肉芽肿（eosinophilic granuloma of bone,EGB）是一种发生于骨组织的良性肿瘤性疾病,该病的病理改变主要包括局部组织细胞增生和嗜酸性细胞的浸润,好发于青少年。EGB的发病率极低,临床表现和影像学表现无明显特异性,容易被误诊或漏诊,因此临床上对该病的诊断尚无标准,但在病理学上EGB具有特殊的表现,因此可根据病理学检查明确对该病的诊断。

关键词：嗜酸性肉芽肿组织细胞增生骨组织病理学检查 granuloma 嗜酸性细胞病例报告文献回顾影像学检查 eosinophilic

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“速发型”颅骨嗜酸性肉芽肿1例并文献复习

临床神经外科杂志 2016年第5期13卷 372-373页

作者：骆杨徐义昌许兴赵昌平钱进徐英纳张勇陶振玉安徽省宣城市人民医院神经外科 242000

颅骨嗜酸性肉芽肿（skull eosinophilic granuloma,SEG）是一种原因不明的全身性骨病,属于朗罕细胞组织增生症中最常见的一种,多见于儿童和青少年;好发于颅骨,以额骨、顶骨和枕骨多见,并以骨质破坏、组织细胞增生及嗜酸性粒细胞浸润等... 详细信息

颅骨嗜酸性肉芽肿（skull eosinophilic granuloma,SEG）是一种原因不明的全身性骨病,属于朗罕细胞组织增生症中最常见的一种,多见于儿童和青少年;好发于颅骨,以额骨、顶骨和枕骨多见,并以骨质破坏、组织细胞增生及嗜酸性粒细胞浸润等为特点。由于本病在临床上较为少见.

关键词：速发型朗罕细胞 eosinophilic granuloma 组织细胞增生 skull 组织增生骨病 Langerhans 组织细胞浸润

Respiratory System Pleura

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China Medical Abstracts(Internal Medicine) 2009年第3期26卷 153-153页

KIDNEY AND URINARY TRACT

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China Medical Abstracts(Internal Medicine) 1999年第4期16卷 215-215页

作者： XU Man Dept Pathol, Beijing Med Univ, Beijing, 100083.

Objective: To study the relationship between insulin-like growth factor-1 (IGF-1), basic fibroblast growth factor (bFGF) and the pathological changes in uric acid nephropathy. Methods: In the pathological progress of ... 详细信息

关键词： adenine granuloma FGFR injured tubular sized stain

Investigation of Diagnostic Problems in Midline Malignant Reticulosis

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华西医科大学学报 1986年第4期 293-293页

作者： Chen Wenbin, et al. Department of Internal Medicine, West China University of Medical Sciences.

Ten cases of midline malignant reticulosis(MMR)verified by biopsy are reported. Thediagnosis of MMR is based on: (1) charac-teristic clinical manifestations including feverand necrotic or destructive lesions in themidline of the upper respiratory tract; (2)specific pathological changes consisting ofinfiltration of inflammatory cells of variouskinds beneath the tissue with marked coag-

关键词： necrotic verified beneath exclusion destructive biopsy marked giant granuloma infiltration