检索结果-南通市图书馆

Characteristics of Glucose and lipid metabolism and the interaction between gut microbiota and colonic mucosal immunity in pigs during cold exposure

引用

畜牧与生物技术杂志:英文版 2023年第5期14卷 2158-2179页

作者： Teng Teng Guodong Sun Hongwei Ding Xin Song Guangdong Bai Baoming Shi Tingting Shang College of Animal Science and Technology Northeast Agricultural UniversityHarbin 150030China

Background Cold regions have long autumn and winter seasons and low ambient temperatures.When pigs are unable to adjust to the cold,oxidative damage and inflammation may develop.However,the differences between cold and non-cold adaptation regarding Glucose and lipid metabolism,gut microbiota and colonic mucosal immunological features in pigs are unknown.This study revealed the glucose and lipid metabolic responses and the dual role of gut microbiota in pigs during cold and non-cold adaptation.Moreover,the regulatory effects of dietary glucose supplements on Glucose and lipid metabolism and the colonic mucosal barrier were evaluated in cold-exposed pigs.Results Cold and non-cold-adapted models were established by Min and Yorkshire pigs.Our results exhibited that cold exposure induced glucose overconsumption in non-cold-adapted pig models(Yorkshire pigs),decreasing plasma glucose concentrations.In this case,cold exposure enhanced the ATGL and CPT-1αexpression to promote liver lipolysis and fatty acid oxidation.Meanwhile,the two probiotics(Collinsella and Bifidobacterium)depletion and the enrichment of two pathogens(Sutterella and Escherichia-Shigella)in colonic microbiota are not conducive to colonic mucosal immunity.However,glucagon-mediated hepatic glycogenolysis in cold-adapted pig models(Min pigs)maintained the stability of glucose homeostasis during cold exposure.It contributed to the gut microbiota(including the enrichment of the Rikenellaceae RC9 gut group,[Eubacterium]coprostanoligenes group and WCHB1-41)that favored cold-adapted metabolism.Conclusions The results of both models indicate that the gut microbiota during cold adaptation contributes to the protection of the colonic mucosa.During non-cold adaptation,cold-induced glucose overconsumption promotes thermogenesis through lipolysis,but interferes with the gut microbiome and colonic mucosal immunity.Furthermore,glucagon-mediated hepatic glycogenolysis contributes to glucose homeostasis during cold exposure.

关键词： Cold exposure Colonic mucosal immunity Fatty acid oxidation Glucose and lipid metabolism Gut microbiota Pig model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of Low Frequency Electro-acupuncture on Glucose and lipid metabolism in Unmarried PCOS Women:A Randomized Controlled Trial

引用

Chinese Journal of Integrative Medicine 2021年第10期27卷 737-743页

作者： DONG Hao-xu WANG Qing WANG Zhi WU Xiao-ke CHENG Ling ZHOU Zhong-ming YANG Li Yl Ping HUANG Dong-mei Institute of Integrated Traditional Chinese and Western Medicine Tongji HospitalHuazhong University of Science and TechnologyWuhan(430030)China Department of Traditional Chinese Medicine Tongji HospitalHuazhong University of Science and TechnologyWuhan(430030)China Department of Rehabilitation Center of Wuhan Puren Hospital Affiliated Hospital of Wuhan University of Science and TechnologyWuhan(430081)China Department of Obstetrics and Gynecology First Affiliated HospitalHeilongjiang University of Chinese MedicineHarbin(150040)China Department of Acupuncture and Moxibustion East HospitalTongji UniversityShanghai(200120)China Department of Obstetrics and Gynecology Hubei University of Traditional Chinese MedicineWuhan(430060)China

Objective:To explore the effect of electro-acupuncture(EA)on Glucose and lipid metabolism in unmarried patients with polycystic ovary syndrome(PCOS).Methods:Fifty-four PCOS patients were equally randomized into true acupuncture group and sham acupuncture group(control)for totally 16 weeks of treatment by random method with a computerized randomization program.Patients in true acupuncture group accepted traditional acupuncture methods with EA and two sets of acupoint groups were used alternatively.The first set consisted of Zhongji(CV 3),Qihai(CV 6),Guilai(ST 29),Sanyinjiao(SP 6),Yinlingquan(SP 9),Hegu(LI4)and Baihui(GV 20),and the second set consisted of Tianshu(ST 25),ST 29,CV 3,CV 6,SP 6,Taichong(LR 3),Neiguan(PC)6 and GV 20.Patients in the sham acupuncture group accepted shallow acupuncture methods through EA without electricity at 4 non-meridian points in each shoulder and upper arm.Outcome measures included body mass index(BMI),waist-hip-ratio(WHR),oral glucose tolerance test(OGTT),insulin release test,Glucose and lipid metabolism indicators such as total cholesterol(TC),triglycerides,high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol,adiponectin,leptin,visfatin,resistin,and interleukin(IL-6).Results:Twenty-six subjects in the true acupuncture group and 20 subjects in the sham group completed the clinical trial.After 16 weeks of treatment,no significant difference in the outcome measures were observed between the two groups(P>0.05).However,as compared with baseline data,a reduction in weight,BMI,hipline,WHR,fasting glucose,homeostatic model assessment of insulin sensitivity,visfatin and HDL-C,and an increase in resistin and IL-6 were observed in the true acupuncture group(PGlucose and lipid metabolism.Moreover,the sham acupuncture may be not completely ineffective.Sham acupuncture m

关键词： electro-acupuncture Glucose and lipid metabolism sham acupuncture visfatin polycystic ovary syndrome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sucrose-free hawthorn leathers formulated with fructooligosaccharides and xylooligosaccharides ameliorate high-fat diet induced inflammation, Glucose and lipid metabolism in liver of mice

引用

Food Science and Human Wellness 2022年第4期11卷 1064-1075页

作者： Tao Li Lihan Xu Qiaojuan Yan Jun Liu Zhengqiang Jiang Key Laboratory of Food Bioengineering(China National Light Industry) College of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China Beijing Advanced Innovation Center for Food Nutrition and Human Health College of EngineeringChina Agricultural UniversityBeijing 100083China

High sucrose content in traditional hawthorn leathers limits the potential consumption, particularly for elders and diabetics. In this study, sucrose-free hawthorn leathers were formulated with 75% fructooligosaccharides(FOS) and 25% xylooligosaccharides(XOS)(HLF75), which exhibited comparable morphology and sensory properties to the traditional ones. Then, the anti-obesity activity of HLF75 was investigated using high-fat diet(HFD) fed C57BL/6J mice. Comparing with traditional hawthorn leathers, HLF75 supplementation in HFD significantly decreased the levels of blood glucose and serum lipid. The histomorphologies of liver and subcutaneous fat tissues were ameliorated by HLF75, as well as the down-regulated m RNA expression levels of IL-1β, Nos2 and Cox-2 in the liver. M oreover, the protein levels of M y D88 and NF-κB in the liver were suppressed by HLF75 treatment with decreased F4/80-positive macrophage number. Ho wever, the expression levels of PI3K, phosphorylated-AKT(Thr308), and phosphorylated-m TOR(Ser2448) proteins related to glucose metabolism were increased in the liver. Moreover, fat synthesis-related gene expression in HLF75-fed mice was suppressed while expressions of lipolysis genes were improved. Thus, HLF75 supplementation alleviated HFD-induced obesity through the alleviation of inflammation and restoration of the disturbed Glucose and lipid metabolism. Functional oligosaccharides could be effective sucrose substitutes in hawthorn leathers and enable their potential utilization as functional foods.

关键词： Hawthorn leathers Functional oligosaccharides Inflammatory responses Glucose and lipid metabolism Anti-obesity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of vitamin D supplementation on Glucose and lipid metabolism in patients with type 2 diabetes mellitus and risk factors for insulin resistance

引用

World Journal of Diabetes 2023年第10期14卷 1514-1523页

作者： Li-Jie Sun Ji-Xuan Lu Xin-Yu Li Tian-Sheng Zheng Xiao-Rong Zhan Department of Endocrinology First Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Endocrinology Southern University of Science and Technology HospitalShenzhen 518071Guangdong ProvinceChina

BACKGROUND Type 2 diabetes mellitus(T2DM)is a chronic metabolic disease featured by insulin resistance(IR)and decreased insulin secretion.Currently,vitamin D deficiency is found in most patients with T2DM,but the relationship between vitamin D and IR in T2DM patients requires further investigation.AIM To explore the risk factors of IR and the effects of vitamin D supplementation on Glucose and lipid metabolism in patients with T2DM.METHODS Clinical data of 162 T2DM patients treated in First Affiliated Hospital of Harbin Medical University between January 2019 and February 2022 were retrospectively analyzed.Based on the diagnostic criteria of IR,the patients were divided into a resistance group(n=100)and a non-resistance group(n=62).Subsequently,patients in the resistance group were subdivided to a conventional group(n=44)or a joint group(n=56)according to the treatment regimens.Logistic regression was carried out to analyze the risk factors of IR in T2DM patients.The changes in Glucose and lipid metabolism indexes in T2DM patients with vitamin D deficiency were evaluated after the treatment.RESULTS Notable differences were observed in age and body mass index(BMI)between the resistance group and the non-resistance group(both Pglucose(2hPG),fasting blood glucose(FBG),and glycosylated hemoglobin(HbA1c)than the non-resistance group(all P<0.0001).Additionally,the resistance group demonstrated a higher triglyceride(TG)level but a lower high-density lipoprotein-cholesterol(HDL-C)level than the non-resistance group(all P<0.0001).The BMI,TG,HDL-C,25(OH)D_(3),2hPG,and HbA1c were found to be risk factors of IR.Moreover,the posttreatment changes in levels of 25(OH)D_(3),2hPG,FBG and HbA1c,as well as TG,total cholesterol,and HDL-C in the joint group were more significant than those in the conventional group(all P<0.05).CONCLUSION Patients with IR exhibit significant abnormalities i

关键词： Vitamin D Type 2 diabetes mellitus Glucose and lipid metabolism Insulin resistance Risk factors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Mogroside V on Glucose and lipid metabolism in High Fat Diet Mice

引用

Medicinal Plant 2022年第3期13卷 36-38,42页

作者： Riming WEI Haiping LIU Pharmacology Laboratory of Prevention and Treatment of High Incidence of Disease Guilin Medical University Guilin 541199 China

[Objectives]To explore the effects and mechanism of mogroside V(MV)on Glucose and lipid metabolism in high-fat diet(HFD)mice.[Methods]The experiment fed mice with high-fat diet for 8 weeks,and 40 mice with successful modeling were randomly divided into normal group,model group,and MV dose group(100,200 mg/kg),with 10 mice in each group.From the ninth week,the MV dose group was given intragastric administration,and the normal group and the model group were given an equal volume of distilled water by intragastric administration for 6 weeks,then killed and blood samples and livers were collected.Serum triglycerides(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),free fatty acids(FFA),Advanced glycation end products(AGE-P)-peptides(AGE-P)and glycosylated hemoglobin(HbA1c)content,and TG and hepatic glycogen content in liver were detected by biochemical method.Fasting blood glucose(FBG)was measured by glucose oxidase method.The fasting serum insulin(FINS)content was detected by enzyme-linked immunosorbent assay(ELISA),and the insulin resistance index(HOMA-IR)was calculated.Oil red O staining was used to observe the fat deposition in liver tissue.[Results]MV(100,200 mg/kg)dose groups could significantly down-regulate the contents of TC,TG,LDL-C,FBG,FINS,AGE-P and HbA1c and HOMA-IR,and up-regulate HDL-C and hepatic glycogen content and reduce the fat deposits.[Conclusions]The mechanism of MV regulating Glucose and lipid metabolism in mice may be related to the regulation of insulin resistance.

关键词： Mogroside V(MV) High fat diet(HFD) Glucose and lipid metabolism Insulin resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Decabromodiphenyl ether causes insulin resistance and Glucose and lipid metabolism disorders in mice

引用

World Journal of Diabetes 2021年第8期12卷 1267-1281页

作者： Ayiguli Alimu Haiqiemuhan Abudureman Yong-Zhi Wang Mei-Yan Li Jia-Sui Wang Zao-Ling Liu Department of Epidemiology and Health Statistics School of Public HealthXinjiang Medical UniversityUrumqi 0991Xinjiang Uygur Autonomous RegionChina Department of Public Health Xinjiang Second Medical CollegeCremayi 834000Xinjiang Uygur Autonomous RegionChina

BACKGROUND Decabromodiphenyl ether(BDE-209)is the most commonly used brominated flame retardant.Recently,BDE-209 has been suspected of being an environmental risk factor for metabolic diseases such as obesity,insulin resistance(IR),type 2 diabetes mellitus,and hypertension.AIM To investigate the effects of BDE-209 on IR and Glucose and lipid metabolism in C57BL/6 mice.METHODS Adult male C57BL/6 mice were randomly divided into high,medium-high,medium,medium-low,and low dose BDE-209 groups,and a control group(n=6 per group),which received 1000,800,600,450,300,and 0 mg/kg BDE-209,respectively.After BDE-209 exposure for 60 d,the mice were fasted overnight,and then sacrificed to obtain tissues.An automatic biochemical analyzer was used to detect serum triglyceride(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),and high density lipoprotein cholesterol(HDL-C);enzymelinked immunosorbent assay kits were used to detect fasting serum insulin(FINS),leptin(LEP),and adiponectin(Adp)levels;a blood glucose meter was used to detect fasting blood glucose(FBG).Morphological changes of the liver were observed by hematoxylin and eosin staining.Real-time quantitative polymerase chain reaction and Western blot were used to determine the messenger ribonucleic acid(mRNA)and protein levels,respectively,of LEP,Adp,and peroxisome proliferators activated receptor-γ(PPARγ)in mouse liver and adipose tissues.RESULTS There was a statistically significant difference in the weight of mice in each group after 45 and 60 d of exposure(P<0.05).After 60 d of exposure,the weight of liver and adipose tissues in the exposure groups were greater than that of the control group(P<0.05).The liver tissue structure was disordered and the liver tissues were accompanied by local inflammatory cell infiltration in the high,mediumhigh,and medium dose BDE-209 groups.The levels of FINS,insulin sensitivity index,Adp,and HDL-C were decreased in the BDE-209 group compared with the control group,as were the mRNA and protein levels of Adp in liver and

关键词： Decabromodiphenyl ether Adipokine Glucose and lipid metabolism Protein expression mRNA expression Insulin resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between polymorphism of MC4R rs489693 gene and disorder of Glucose and lipid metabolism in schizophrenia patients treated with olanzapine

引用

Journal of Hainan Medical University 2020年第17期26卷 43-46页

作者： Tian-Dao Wang Ming Pan Xiang-Lai Liu Qin-Wei Xu Yu Zhou 不详

Objective:To investigate the effect of Melanocortin four receptor,MC4R rs489693 polymorphism on Glucose and lipid metabolism in schizophrenia patients treated with Olanzapine for 12 weeks.Methods:171 patients with schizophrenia were divided into AA Group(N=12),AC group(N=59)and CC Group(N=100)according to the polymorphism of MC4R gene at 489693 locus detected by DNA sequencing.Blood glucose and lipid levels were measured before and 12 weeks after treatment,the differences of variables among the 3 groups were compared,and the incidence of glucose and lipid abnormalities after treatment was statistically analyzed.Results:After 12 weeks of treatment,the net increase of blood glucose in AA group was greater than that in CC group(Pglucose and at least one dyslipidemia in AA Group was higher than that in AC and CC group(all PGlucose and lipid metabolism in schizophrenia treated with olanzapine.

关键词： Schizophrenia Olanzapine Melanocortin 4 receptor Glucose and lipid metabolism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

NLRP3 Inflammasome in Relation to Glucose and lipid metabolism, and Insulin Resistance in Diabetes and Pre-Diabetes

引用

Yangtze Medicine 2023年第1期7卷 1-10页

作者： Shujuan Hu Dang Liu Yinqi Zhang Yiting Ding Bingqing Li Xianwang Wang School of Education and Physical Education Yangtze University Jingzhou China School of Physical Education and Science Jishou University Jishou China Department of Biochemistry and Molecular Biology Center for Molecular Medicine Health Science Center Yangtze University Jingzhou China Clinical Laboratory The Second School of Clinical Medicine and Jingzhou Central Hospital Yangtze University Jingzhou China

Aims: To investigate the relationship among NLRP3 inflammasome, Glucose and lipid metabolism, and insulin resistance (IR) in the serum of patients with diabetes and pre-diabetes. Methods: A total of 100 patients with abnormal blood glucose divided into the pre-diabetes mellitus (PDM) group (N = 46) and the type 2 diabetes mellitus (T2DM) group (N = 54). 20 normoglycemic subjects (NG, N = 20) were selected as a control group. The serum levels of Glucose and lipid metabolism, IR, and the expression of NLRP3, ASC and Caspase-1 were measured. Besides, the correlations of NLRP3 inflammasome with Glucose and lipid metabolism, and IR were analyzed. Results: Compared with the NG group, the levels of NLRP3, ASC, Caspase-1, FBG, HbA1C, TG, LDL-C, FINs, and HOMA-IR were higher (P β were lower (P P β were seen (P P β. Regression analysis further showed that blood glucose related indexes, FINs, and NLRP3 have made a decisive contribution to IR. Conclusions: Collectively, this evidence suggested that NLRP3 is closely related to Glucose and lipid metabolism, and IR, and activated in PDM and T2DM.

关键词： Type 2 Diabetes Mellitus Pre-Diabetes Mellitus NLRP3 Glucose and lipid metabolism Insulin Resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of marine collagen peptides on Glucose and lipid metabolism and markers of metabolic nuclear receptors in hypertensive patients with type 2 diabetes

Effects of marine collagen peptides on glucose and lipid met...

引用

中国食品科学技术学会第八届年会暨第六届东西方食品业高层...

作者： Zhu Cui-Feng~(a,b) Li Guan-Zhi~b Peng Hong-Bin~1 Zhang Fan~2 Chen Yun~2 Lu Hong~2 LI Yong~(1*) (a Department of Nutrition and Food Hygiene,School of Public Health,Peking University,Beijing 10083, China b Department of Nutrition,Shenzhen Hospital of Peking University,Shenzhen 518036,China.)

＜正＞Objective:This study was attempted to determine the effects of marine collagen peptides（MCPs） on Glucose and lipid metabolism and markers of three metabolic nuclear receptors,peroxisome proliferator -activated receptor（PPARs）,liver X receptor（LXRs）and farnesoid X receptor（FXRs）,in hypertensive patients with type 2 diabetes.Methods:The study population consisted of one hundred hypertensive patients with type 2 diabetes and fifty healthy subjects recruited from local communities in Shenzhen,China.Diabetic patients with hypertension were randomized into intervention group（n=50,group A）and non-intervention group（n=50,group B）whereas fifty healthy subjects were assigned to control group.MCPs or placebo （water-soluble starch）were respetively given to group A and group B before breakfast and bedtime at a dose of 6.5g over a period of three months.Fasting serum samples were analyzed for levels of blood glucose, insulin,serum lipid,uric acid,glycosylated hemoglobin（GHbA1c）,high sensitivity C-Reactive protein （hs-CRP）,serum creatinine and markers of metabolic nuclear receptor,including free fatty acid,cytochrome P450,leptin,resistin,adiponectin,bradykinin,NO and prostacyclin before intervention,1.5 months,and 3 months after intervention.New occurrence of acute or chronic complications developed during the study such as hypoglycemia and diabetic ketoacidosis were recorded and compared among different groups.Results:Before intervention,the levels of fasting blood glucose,insulin,triglyceride in group A and B were higher than those of healthy controls while levels of HDLc in group A and group B were much lower than that of healthy controls.Throughout the study,the concentrations of free fatty acid,cytochrome P450,resistin and bradykinin in group A and B were much higher than those in controls,yet no statistical differences were noted between group A and B.Levels of prostacyclin in group A and B were higher than those of normal controls either before or after intervention.After treated with MCPs or placebo for 1.5 months an

关键词： marine collagen peptide Glucose and lipid metabolism peroxisome proliferator-activated receptor（PPAR） liver X receptor farnesoid X receptor metabolic nuclear receptor

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Effects of marine collagen peptides on Glucose and lipid metabolism and markers of metabolic nuclear receptors in hypertensive patients with type 2 diabetes

Effects of marine collagen peptides on glucose and lipid met...

引用

北京市营养学会第四届会员代表大会暨膳食与健康研讨会

作者： Zhu Cui-Feng~(1,2),Li Guan-Zhi~2,Peng Hong-Bin~1,Zhang Fan~2,Chen Yun~2,Lu Hong~2,LI Yong~(1*) 1.Department of Nutrition and Food Hygiene,School of Public Health,Peking University,Beijing 10083,China 2.Department of Nutrition,Shenzhen Hospital of Peking University,Shenzhen 518036,China.

Objective:This study was attempted to determine the effects of marine collagen peptides(MCPs) on Glucose and lipid metabolism and markers of three metabolic nuclear receptors,peroxisome proliferator-activated receptor(PPARs),liver X receptor(LXRs) and farnesoid X receptor(FXRs),in hypertensive patients with type 2 diabetes. Methods:The study population consisted of one hundred hypertensive patients with type 2 diabetes and fifty healthy subjects recruited from local communities in Shenzhen,China.Diabetic patients with hypertension were randomized into intervention group(n=50,group A) and non-intervention group(n=50, group B) whereas fifty healthy subjects were assigned to control group.MCPs or placebo(water-soluble starch) were respetively given to group A and group B before breakfast and bedtime at a dose of 6.5g over a period of three months.Fasting serum samples were analyzed for levels of blood glucose,insulin,serum lipid,uric acid,glycosylated hemoglobin(GHbAlc),high sensitivity C-Reactive protein(hs-CRP),serum creatinine and markers of metabolic nuclear receptor,including free fatty acid,cytochrome P450,leptin, resistin,adiponectin,bradykinin,NO and prostacyclin before intervention,1.5 months,and 3 months after intervention.New occurrence of acute or chronic complications developed during the study such as hypoglycemia and diabetic ketoacidosis were recorded and compared among different groups. Results:Before intervention,the levels of fasting blood glucose,insulin,triglyceride in group A and B were higher than those of healthy controls while levels of HDLc in group A and group B were much lower than that of healthy controls.Throughout the study,the concentrations of free fatty acid,cytochrome P450, resistin and bradykinin in group A and B were much higher than those in controls,yet no statistical differences were noted between group A and B.Levels of prostacyclin in group A and B were higher than those of normal controls either before or after intervention.After treated with MCPs or placebo for 1.5 months

关键词： marine collagen peptide Glucose and lipid metabolism peroxisome proliferator-activated receptor（PPAR） liver X receptor farnesoid X receptor metabolic nuclear receptor

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：