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glomus tumor of the gastric body:helical CT findings

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Chinese Medical Journal 2007年第14期120卷 1289-1291页

作者： HU Xiao-yun HU Chun-hong FANG Xiang-ming ZHANG Tong-hua Medical Imaging Center First Affiliated Hospital Soochow University Suzhou 215006 China

glomus tumors, also known as glomangiomas, are rare and originate in the neuromyoarterial glomus, a normal arteriovenous shunt which is abundantly supplied with nerve fibers and fulfills a temperature-regulating function. The classic location of glomus tumor is the subungual region, but the tumor can occur elsewhere in the skin, soft tissues, nerves, stomach, nasal cavity, and trachea.In the gastrointestinal （GI） tract the tumor occurs more often in the stomach than other parts, and typically occurs as a solitary submucosal nodule in the antrum. We reported a case of glomus tumor originating from the greater curvature of stomach which was studied with contrast-enhanced helical computed tomography （CT） and described the characteristic helical CT findings of the rare lesion.

关键词： glomus tumor computed tomography diagnostic imaging

Bronchial glomus tumor with calcification: A case report

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World Journal of Clinical Cases 2021年第14期9卷 3320-3326页

作者： Ying Zhang Qiu-Ping Zhang Ying-Qun Ji Jian Xu Department of Pulmonary and Critical Care Medicine The First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Pathology The First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Pulmonary and Critical Care Medicine Shanghai East HospitalTongji University School of MedicineShanghai 200120China Department of Pulmonary and Critical Care Medicine Dalian Municipal Central Hospital Affiliated of Dalian Medical UniversityDalian 116033Liaoning ProvinceChina

BACKGROUND glomus tumors(GTs),defined by modified smooth cells and normal glomus body cells,usually present with a small mass occurring in the soft tissue or dermis of an extremity,especially in the subungual region.However,other unusual sites,such as the respiratory tract,have also been reported.They are usually sporadic.Their imaging findings are usually nonspecific and likely to appear as a well-delineated round mass that usually lacks calcification.To our knowledge,we report the first case of bronchial GTs with calcification,reminding clinicians and radiologists that GT is one of the differential diagnoses when a calcified nodular mass is found.CASE SUMMARY We report a case of a 33-yr-old Chinese man with cough and sputum for 11 d and hemoptysis for 5 d.Chest computed tomography revealed a calcified nodular lesion on the compressed posterior wall of the lower left main bronchus and bronchiectasis in the lower lobe of the left lung.To confirm the characteristics of calcified nodules,we performed fiberoptic bronchoscopy.The tumor tissue from the biopsy of bronchial mucosal lesions established the diagnosis of GT.Because the patient had no life-threatening symptoms,he was not treated with surgery.Clinical follow-up for 25 mo showed that the patient survived well without any discomfort.CONCLUSION Bronchial GTs are usually not accompanied by calcification on computed tomography scans.To our knowledge,we report the first calcified bronchial GT.We recommend that clinicians consider GT as a possible differential diagnosis when a calcified mass of the bronchi is found.

关键词： glomus tumor Imaging Calcified tumor Bronchus Case report

Tracheal glomus tumor： two cases with bronchoscopic intervention

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Chinese Medical Journal 2014年第1期127卷 189-190页

作者： Xiong Wei Cai Cunliang Zhou Yunzhi Zhang Nan Wang Hongwu Department of Internal Oncology Meitan General Hospital Beijing100028 China

glomus tumors are neoplasms derived from specialized cells of glomus bodies surrounding arteriovenous anastomoses.Although most of them are benign,aggressive cases have been described.glomus tumors can be found throughout the body but are most highly concentrated in the digits,palms,and soles of the feet.It is rare in lung and trachea and the optimal therapy has not been thoroughly described.

关键词： glomus tumor bronchoscopy

Recurrent glomangioma("true"glomus tumor)of the middle ear and mastoid

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2019年第4期5卷 175-179页

作者： Adam C.Kaufman Jason A.Brant Neil N.Luu Virginia A.LiVolsi Douglas C.Bigelow Department of Otorhinolaryngology Head and Neck Surgery Hospital of the University of PennsylvaniaPhiladelphiaPAUSA Perelman School of Medicine at the University of Pennsylvania PhiladelphiaPAUSA Department of Pathology and Laboratory Medicine Hospital of the University of PennsylvaniaPhiladelphiaPAUSA

Objective:To review current literature and experience with glomangiomas,or true glomus tumors of the middle ear and mastoid as well asto report on the exceptionally rare case of a glomangiomastemming from the middle ear space with multiple recurrences.Methods:Review of existing world literature and description of personal experience with rare cases of a glomangioma of the middle ear and mastoid.Results:Review of existing literature revealed two cases of patients presenting with tinnitus and hearing loss refractory to medical management.Both patients were ultimately diagnosed with glomangioma on histopathology.Complete surgical excision is thought to be curative.Patient:A 36-year-old woman presented with a rare case of a glomangioma of the middle ear presenting with unilateral hearing loss.She was noted to have a mass behind the tympanic membrane.Imaging revealed a diffuse mass filling the mastoid air cells.Imaging characteristics and histology were consistent with a glomangioma.Intervention:Initial resection via mastoidectomy using a postauricular approach.The tympanic membrane was reconstructed with temporalis tissue.Follow-up revision tympanomas-toidectomy was performed upon recurrence of disease.The chorda tympani were sacrificed due to tumor involvement.The incus and head of the malleus were removed to gain better access to the tumor.The ossicular chain was reconstructed with a Goldenberg Total Ossicular Prosthesis.Main outcome measure:Recurrence of disease.Follow-up:In the 67 months since her most recent surgery,there has been no evidence of recurrence by CT or physical exam.Conclusion:Glomangioma of the middle ear represents an exceptionally rare entity that can present in a similar fashion to a paraganglioma.

关键词： Glomangioma glomus tumor Glomuvenous malformation Middle ear tumor Unilateral hearing loss

glomus tumor of the Kidney: A Case Report with CT, MRI, and Histopathological Findings

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Open Journal of Urology 2016年第5期6卷 80-85页

作者： Jillian W. Lazor Thomas J. Guzzo Zhanyong Bing Priti Lal Parvati Ramchandani Drew A. Torigian Department of Radiology Hospital of the University of Pennsylvania Philadelphia PA USA Department of Surgery Hospital of the University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Hospital of the University of Pennsylvania Philadelphia PA USA

We describe the computed tomographic (CT) and magnetic resonance imaging (MRI) features of a very rare renal neoplasm, a glomus tumor. Our patient was a 68-year-old woman with a history of high grade T1 stage bladder cancer, status post intravesical Bacillus Calmette-Guérin (BCG) therapy and left ureteral stent placement, who presented for routine follow-up imaging evaluation of the urothelial tract. Computed tomographic urography (CTU) incidentally demonstrated a 1.7 cm well-circumscribed, non-calcified, non-fat containing lesion in the left renal cortex with arterial phase continuous peripheral rim enhancement and central hypoattenuation relative to enhanced renal parenchyma. Subsequent MRI showed the lesion to be isointense in signal intensity relative to the renal parenchyma on T1-weighted imaging and hyperintense on T2-weighted imaging. No macroscopic fat or microscopic lipid was seen within the lesion, and there were no foci of susceptibility artifact on T1-weighted images. Diffusion-weighted and apparent diffusion coefficient images demonstrated no restricted diffusion. Contrast-enhanced images demonstrated continuous peripheral rim enhancement in the arterial phase and persistent rim enhancement with partial centripetal fill in of enhancement on venous phase images, similar to the pattern seen on CT. Partial left nephrectomy was performed for the suspected solid renal neoplasm. Histopathological assessment was diagnostic of a renal glomus tumor.

关键词： glomus tumor Kidney Renal Computed Tomography (CT) Magnetic Resonance Imaging (MRI)

glomus tumor in the thigh:a case report

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Glomus tumor in the thigh:a case report

Glomangiomatosis-immunohistochemical study:A case report

2013中国工程院科技论坛暨浙江省骨科学学术年会

作者：王宣伟

glomus tumors are rare neoplasms that originate from the glomus body of the reticular dermis.Most glomus tumors occur in the subungual region of the distal phalanx.In this report,we describe an extremely rare case of glomus tumor located in the thigh.The final diagnosis was established by pathological examination of the surgical resection specimen.

关键词： glomus tumor soft tissue tumor lower extremity

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World Journal of Clinical Cases 2022年第16期10卷 5406-5413页

作者： Ruo-Chen Wu Ying-Hua Gao Wen-Wen Sun Xiang-Yun Zhang Shu-Peng Zhang Department of Pathology The Second Affiliated Hospital of Shandong First Medical UniversityTaian 271000Shandong ProvinceChina Department of Pathology The First People’s Hospital of Jining CityJining 272000Shandong ProvinceChina

BACKGROUND Glomangiomatosis(also known as diffuse glomus tumor)is extremely rare,accounting for only 5%of glomus tumors.The prevalence of glomus tumors is only 2%of soft tissue tumors.Lesions can recur after resection.Although growth may be diffuse or infiltrating and invasive,definitive identifying standards for malignant glomus tumors are lacking.This article describes a case of glomangiomatosis with many nodular masses in the soft tissues of the right foot and calf.A review of the Chinese and English-language literature is included.CASE SUMMARY A case of glomangiomatosis in a 55-year-old Chinese woman who presented clinically with many nodular masses in the soft tissues of the right foot and calf.The tumor was examined histologically and immunostaining was performed.CONCLUSION Glomangiomatosis occurs most often in young people,in the distal extremities,but is rare.Multiple nodules are even rarer.Only 15 clinicopathological analyses of glomangiomatosis have been reported in the combined Chinese-and Englishlanguage literature.In the present case,microscopically,nested vascular globular cells were observed around the blood vessel wall.Immunohistochemistry revealed diffuse immunoreactivity for smooth muscle actin,vimentin,type Ⅳ collagen,and Bcl-2.Caldesmon,CD34,and calponin were weakly,partially,and slightly positive,respectively.There was no recurrence 1 year after resection.

关键词： Glomangiomatosis glomus tumor Foot and ankle Perivascular tumors Case report

glomus tympanicum removal using transcanal endoscopic assisted surgery:An experience with six cases

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2023年第4期9卷 302-307页

作者： Pradipt Ranjan Sahoo Monalisa Sahu Imran Wasfi Khan Kabikanta Samantaray Department of ENT and Head and Neck Surgery Kalinga Institute of Medical SciencesBhubaneswarOdishaIndia Department of Infectious Diseases Yashoda HospitalsHyderabadIndia

Objective:To evaluate an endoscopic approach in the management of glomus tumor,and also to investigate and evaluate its appropriateness and feasibility.Methods:glomus tumors,also known as paragangliomas,are benign primary tumors of the middle ear.The advent of endoscopic ear surgery has provided new dimensions to the management of this highly vascular tumor.Retrospective analysis of six patients of glomus tympanicum,operated between July 2014 and June 2019,with modified Fisch classification Type A and B1,who were managed by a retroauricular transcanal endoscopic approach.Preoperative and postoperative analysis was done for these patients.Results:The chief complaint was pulsatile tinnitus,which disappeared in five cases and reduced in severity in one of them.Hearing was improved with reduction in air‐bone gap in all the cases.No major complications or recurrence were observed in any of the patients after 12 months of follow‐up.Conclusion:This endoscopic approach serves as a safe and reliable technique for tumor removal.It thus provides postoperative comfort for most of the patients.

关键词： glomus tumor glomus tympanicum pulsatile tinnitus transcanal endoscopic tympanic paraganglioma

Endoscopic ultrasonography diagnosis of gastric glomus tumors

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World Journal of Clinical Cases 2021年第33期9卷 10126-10133页

作者： Bing Bai Chong-Shan Mao Zhen Li Sheng-Li Kuang Oncology Center Henan Provincial People's Hospital(People's Hospital of Zhengzhou University)Zhengzhou 450003Henan ProvinceChina Public Health Medical Center Henan Provincial People's Hospital(People's Hospital of Zhengzhou University)Zhengzhou 450003Henan ProvinceChina Department of Digestive Disease Henan Provincial People's HospitalZhengzhou 450003Henan ProvinceChina

BACKGROUND A gastric glomus tumor is relatively rare,and there is little knowledge on its endoscopic ultrasound findings.AIM To assess the accuracy of endoscopic ultrasonography(EUS)in the diagnosis of gastric glomus tumor and to discuss its value by reviewing the literature.METHODS A retrospective analysis of the EUS characteristics of gastric glomus tumor(such as tumor location,shape,size,echogenicity,homogeneity,margins,layer of origin,and so on)was performed.The study included 12 cases of gastric glomus tumor confirmed by surgery and pathology(7 females and 5 males,age range 36-74 years,average age was 58.2 years).RESULTS All the lesions were located in the gastric antrum(12 cases),protruding into the cavity,with a diameter between 1 and 3.5 cm.glomus tumor of the stomach manifested as a circumscribed and slightly hypoechoic mass in the fourth layer,with an internal heterogeneous echo mixed with hyperechogenic spots and a marginal more hypoechoic halo.Smooth muscle actin,h-caldesmon and vimentin were shown to be positive by immunohistochemistry.CONCLUSION Although glomus tumor of the stomach is relatively rare,a typical glomus tumor of the stomach has characteristic changes under EUS.

关键词： glomus tumor Endoscopic ultrasonography Computed tomography Pathology