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The Place of Nipple-Sparing Mastectomy in the Treatment of Breast Cancer: Review of the Literature

Open Journal of Obstetrics and Gynecology 2021年第12期11卷 1752-1769页

作者： Abdallah El Farouqi Anas Boumzough Department of Obstetrics and Gynecology Agadir Faculty of Medicine and Pharmacy UHC Agadir Morocco

Introduction: Mastectomy with conservation of the nipple-areola complex (NAC) in breast cancer care has been controversial with regards to the oncological safety of this procedure and the risk of complications including NAC necrosis. Aim: The objective of this study is to assess, through a literature review, the safety and reliability of a conservative NAC mastectomy in breast cancer treatment, paying attention to the rate of local recurrence and complications. Methods: A review of the literature was conducted from PubMed data, and articles published between January 2007 and December 2017, using the terms “nipple-sparing mastectomy”, “breast cancer”, “local recurrence”, “necrosis of the nipple”, “global complications”. The articles were analyzed with regards to the following parameters of evaluation: local recurrence, recurrence rate at NAC level, global complication rates and nipple necrosis rates. Results: In the 36 studies we selected, the average rate of local recurrence was 3.23%. The average rate of recurrence at the NAC was 0.81%. The average rate of complications was 20%. The average rate of necrosis of the NAC was 5.9%. The main factors of these recurrences were the tumor size > 5 cm and tumor stage > stage II. Conclusion: Conservative mastectomy of the nipple-areola complex offers an aesthetic advantage and oncological sa

关键词： Nipple-Sparing Mastectomy Breast Cancer Local Recurrence Necrosis of the Nipple global complications

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