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Endoscopic findings of gastrointestinal involvement in Chinese patients with Behcet's disease

World Journal of Gastroenterology 2014年第45期20卷 17171-17178页

作者： Jun Zou Yan Shen Da-Nian Ji Song-Bai Zheng Jian-Long Guan Division of Immunology and Rheumatology Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital Research Center on Aging and Medicine Fudan University Center of gastrointestinal Endoscopy Huadong Hospital Fudan University Division of Gastroenterology Huadong Hospital Fudan University

AIM:To report the incidence,clinical features and outcomes of gastrointestinal(GI)involvement in Behcet’s disease(BD).METHODS:A total of 168 consecutive patients with BD were screened and upper and lower GI endoscopies were performed in 148 *** hundred age-and sex-matched controls were enrolled for ***:Fifty-two(35.1%)patients had GI *** a mean follow-up of 10 mo,ileocecal ulcers had been confirmed in 20 patients,including active ulcer(s)in 18 patients,but no ileocecal ulceration was found in *** symptoms were present in 14 patients with active ulcer(s),while 4 patients with smaller ulcer were *** features of ileocecalulcer were:a single ulcer(50%),larger than 1 cm in diameter(72.2%),and round/oval or volcano-type in shape(83.3%).Compared with patients without GI involvement,less ocular lesions,lower levels of albumin,erythrocyte count and hemoglobin,and higher levels of C-reactive protein and erythrocyte sedimentation rate were confirmed in the intestinal BD *** patients had esophageal ulcers in the BD group but no case in *** other endoscopic findings were similar between the two *** prevalence of Helicobacter pylori infection was similar in both *** patients received an immunomodulator and responded ***:GI lesions commonly occur in Chinese BD *** most frequently involved area is the ileocecal *** ulcer might be a rare but unique lesion.

关键词： Behcet's disease gastrointestinal involve-ment Ulcer Endoscopy Case-controlled

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