检索结果-南通市图书馆

Possible effect of blonanserin on gambling disorder:A clinical study protocol and a case report

World Journal of Clinical Cases 2021年第11期9卷 2469-2477页

作者： Akihiro Shiina Tadashi Hasegawa Masaomi Iyo Division of Medical Treatment and Rehabilitation Chiba University Center for Forensic Mental HealthChiba 260-8670Japan Department of Psychiatry Chiba University HospitalChiba 260-8670Japan Department of Psychiatry Chiba University Graduate School of MedicineChiba 260-8670Japan

BACKGROUND gambling disorder is characterized by excessive and recurrent gambling and can have serious negative social *** several psychotherapeutic and pharmacological approaches have been used to treat gambling disorder,new treatment strategies are *** evidence suggests that dopamine D3 receptor plays a specific role in the brain reward *** To investigate if blonanserin,a dopamine D3 receptor antagonist,would be effective in reducing gambling impulses in patients with gambling *** We developed a study protocol to measure the efficacy and safety of blonanserin as a potential drug for gambling disorder,in which up to 12 mg/d of blonanserin was prescribed for 8 *** A 37-year-old female patient with gambling disorder,intellectual disability,and other physical diseases participated in the pilot *** case showed improvement of gambling symptoms without any ***,blonanserin was discontinued owing to excessive saliva *** This case suggests that blonanserin is potentially an effective treatment for patients with gambling disorder who resist standard therapies,but it also carries a risk of adverse effects. Further studies are needed to confirm the findings.

关键词： Blonanserin gambling disorder Medication Clinical trial protocol D3 receptor Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pilot Study of Problem gambling in Specialized Substance Use disorder Treatment—High Lifetime Prevalence of Problem gambling in Opioid Maintenance Treatment Patients

引用

Open Journal of Psychiatry 2018年第3期8卷 233-243页

作者： Anders Hakansson Johanna Ek Department of Clinical Sciences Lund Lund UniversityLundSweden

Problem gambling is over-represented in patients treated for substance use disorders, but substance-specific prevalence of problem gambling is rarely reported. In specialized addiction treatment facilities for opioid maintenance treatment and for alcohol and prescription drug dependence, respectively, 129 patients were screened for problem gambling using the NODS-CLiP. The lifetime prevalence of problem gambling was markedly higher in opioid maintenance treatment (61 percent) than in alcohol and prescription drug dependence treatment (11 percent, p gambling remained significantly associated with opioid maintenance treatment. The present study demonstrated a very high prevalence of lifetime problem gambling in opioid maintenance treatment patients. This calls for active screening for problem gambling in substance use disorder patients, and mainly in treatment for opioid dependence.

关键词： Substance Use disorder Problem gambling gambling disorder Pathological gambling Comorbidity Opioid Maintenance Treatment Alcohol Dependence

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：