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SPOP acts as the key regulatory hub in hypoxia induced kidney cancer

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Science Foundation in China 2015年第2期23卷 27-27页

Supported by the National Natural Science Foundation of China,the groups of *** Jiang at Beijing Institute of genomics,CAS and *** White from the University of Chicago,reported that the E3ligase adaptor SPOP acts as the key regulatory hub in hypoxia induced tumorigenesis in kidney *** work has been published in Cancer Cell(2014,25(4):455—468).

关键词： genomics tumorigenesis ligase Chicago cytoplasmic Carcinoma mTOR ubiquitin elucidated promoting

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Meetings

World Journal of Gastrointestinal Pharmacology and Therapeutics 2010年第2期1卷 76-76页

Novel mechanism of small RNA-mediated DNA double-strand break repair

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Science Foundation in China 2015年第1期23卷 49-49页

the laboratories of *** Yungui(Beijing Institute of genomics,Chinese Academy of Sciences)and *** Yijun(Center for Plant *** of Life Sciences,Tsinghua University),reported that Ago2 facilitates RadSl recruitment and DNA double-strand break(DSB)repair by homologous recombination,which was published in Cell Research(2014,24(5):532—541).

关键词： repair strand DNA genomics break recombination laboratories homologous RNA cytotoxic

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Events Calendar 2010

World Journal of Gastrointestinal Pharmacology and Therapeutics 2010年第5期1卷 124-124页

Conformational elasticityof TALE-DNA complex

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Science Foundation in China 2015年第2期23卷 17-17页

With the support by the National Natural Science Foundation of China and the Ministry of Science and Technology of China,new progress on the structure and dynamics of TALE(transcription activator-like effector)was reported by a research team led by *** Hongxing at Beijing Institute of genomics,Chinese Academy of Sciences,which was published in Adv Protein Chem Str(2014,94:347—364).

关键词： effector genomics DNA trajectory representative programmable compensation discriminate bases varia

Integrated technologies in the post-genomic era for discovery of bladder cancer urinary markers

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World Journal of Clinical Urology 2013年第3期2卷 20-31页

作者： Sanaa Eissa Marwa Matboli Oncology Diagnostic Unit Medical Biochemistry and Molecular Biology Department Faculty of Medicine Ain Shams University Abassia 11566 Cairo Egypt

The incidence of bladder cancer(BC) continues to rise with high recurrence and mortality rate, especially in the past three decades. The development of accurate and successful BC treatment relies mainly on early diagnosis. BC is a heterogeneous disease reflected by the presence of many potential biomarkers associated with different disease phenotypes. Nowadays, cystoscopy and urinary cytology are considered the gold standard diagnostic tools for BC. There are many limitations to cystoscopy including being invasive, labor-intensive and carcinoma in situ of the bladder may easily be missed. Urinary cytology is still a noninvasive technique with high accuracy in high-grade BC with a median sensitivity of 35%. Furthermore, the need for a sensitive, specific, non invasive, easily accessible BC biomarker is a major clinical need. The field of urinary BC biomarkers discovery is still a rapidly evolving discipline in which more recent technologies are evaluated and often optimized if they are not clinically significant to the urologists. Most of the current strategies for BC urinary biomarker detection depend on integration of information gleaned from the fields of genomics, transcriptomics, proteomics, epigenetics, metabolomics and bionanotechnology. Effort is currently being made to identify the most potentially beneficial urinary biomarkers. The purpose of this review is to summarize and explore the efficacy of gathering the information revealed from the cooperation of different omic strategies that paves the way towards various urinary markers discovery for screening, diagnosis and prognosis of human BC.

关键词： Bladder cancer Urinary biomarkers genomics Proteomics Bionanotechnology Metabolomics Transcriptomics Epigenetics

Brief Guide for Authors

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The Crop Journal 2014年第1期2卷 87-87页

The Crop Journal is a bimonthly scientif ic journal co-sponsored by the Crop Science Society of China and the Institute of Crop Science, Chinese Academy of Agricultural Sciences and China Science Publishing & Media Group Ltd. Published by Elsevier and Science Press. General Requirements Contributions submitted to The Crop Journal must be original works of the author(s) that have not been previously published or simultaneously submitted to any other journals. The experiment related to crop yield should be conducted at least two locations or growing seasons with replications. All the results should be supported by appropriate statistical analyses. Scopes ? Crop Germplasm Resources ? Crop Genetics, genomics and Molecular

关键词： submitted bimonthly genomics Genetics acceptance abbreviation submission reviewers authority citation

What is the purpose of launching the World Journal of Medical Genetics?

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World Journal of Medical Genetics 2011年第1期1卷 1-3页

作者： Hans van Bokhoven Department of Human Genetics Molecular Neurogenetics UnitNijmegen Centre for Molecular Life Sciences and Donders Institute for BrainCognition and BehaviourRadboud University Nijmegen Medical Centre6500 HB NijmegenThe Netherlands

Congratulations to the publisher,members of the editorial board of the journal,all the authors and readers for launching the World Journal of Medical Genetics(WJMG)as a new member of the World series journal family!Following the completion of the Human Genome Project,medical genetic research has seen spectacular progress over the last *** number of genes that have been linked to Mendelian human traits has grown exponentially and currently this process is peaking with the access to robust genome-wide sequencing *** genomics revolution is also seen for elucidation of rare and common DNA variants that increase risk for common *** this fast progress,there is an increasing need for making the results of genetics and genomics studies rapidly and freely available to the larger ***,the decision for inaugurating this new journal is a timely *** WJMG is a peer-reviewed,open-access periodical centered in all aspects of medical genetics research,with multidisciplinary coverage:from human phenotype to genetic and genomic mutations and variations to the study of pathological *** you want to share new results of your research with a link to medical genetics with your peers,you will find the WJMG a good media to publish your papers!

关键词： Medical genetics genomics Biomedical sciences Peer-reviewed Open-access Journal

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Meetings

World Journal of Gastrointestinal Pharmacology and Therapeutics 2010年第4期1卷 88-88页