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Analysis of factors related to early miscarriage after in vitro fertilization embryo transfer

Gynecology and Obstetrics Clinical Medicine 2022年第4期2卷 171-174页

作者： Liying Zuo Yuan Fan Jiajia Ai Li Tian Department of Obstetrics and Gynecology Peking University People's HospitalBeijingChina

Aims:This research aims to explore the factors related to early spontaneous miscarriage after in vitro fertilization and embryo transfer(IVF-ET)pregnancy,and to provide guidance for improving pregnancy ***:We retrospectively analyzed the data for clinical pregnant women(2591 cycles)undergoing IVF-ET at the reproductive center of Peking University People’s Hospital from January 2017 to December 2018;This included 544 ET cycles and 2047 frozen embryo transfer *** analysis of factors associated with early miscarriage in the overall population of IVF/intracytoplasmic sperm injection(ICSI)pregnancies(including fresh and thawing cycles)was ***:The risk of early miscarriage in the 35–39 age group was 1.35 times higher than that in thefresh embryo transfer(OR=1.48[1.08,2.02],p=0.01),while in the fresh cycle,the risk of early miscarriage with high-quality embryos was 0.5 times lower than that with nonhigh quality embryos(OR=0.5[0.27,0.9],p=0.02).In the frozen cycle,the risk of early miscarriage in natural cycle transplantation was 0.73 times that in hormone replacement treatment(HRT)cycle transplantation(OR=0.73[0.54,0.97],p=0.03).Conclusions:Advanced age is an independent risk factor for early miscarriage,while endometrial thickness at the date of transplantation is an independent protective *** risk of early miscarriage in fresh-cycle transplanted embryos is significantly lower than that in frozen embryos,and the number of high-quality embryos in the fresh cycle l

关键词： In vitro fertilization and embryo transfer Early spontaneous miscarriage fresh cycle Frozen cycle

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Pregnancy Outcomes Associated with Ovarian Hyperstimulation Syndrome:A Retrospective Cohort Study of Infertile Women

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Maternal-Fetal Medicine 2023年第3期5卷 144-154页

作者： Ajleeta Sangtani Maryama lsmail Amy Weaver Zaraq Khan Department of Obstetrics and Gynecology Mayo ClinicRochesterMN 55905USA Mayo Clinic Alix School of Medicine Mayo ClinicRochesterMN 55905USA Department of Health Sciences Research Mayo ClinicRochester.MN55905.USA

Objective To assess the relationship between ovarian hyperstimulation syndrome(OHSS)and adverse outcomes using population-based data in the United *** hypothesis is that patients with OHSS were more likely to deliver preterm and more likely to have hypertensive *** This retrospective cohort study identified 94 patients with OHSS and 183 matched referents in eight counties in *** were collected regarding pregnancy history,infertility treatment,and pregnancy *** the Rochester Epidemiology Project,study subjects were identified from female patients,aged 18 to 49 years,who were diagnosed with infertility from January 2,1995 to December 1,2017,and had a pregnancy greater than 20 weeks'*** primary outcome was preterm delivery or hypertensive disorder of pregnancy incidence in the OHSS group when compared with control ***-squared test,t test,and multivariate logistic models were used where *** Patients with OHSS were more likely to deliver preterm(odds ratio,2.14;95%confidence interval,1.26–3.65;Pfresh transfer compared with a freeze all and subsequent frozen transfer(odds ratio,3.03,95%confidence interval,1.20–7.66,P=0.02).Conclusion OHSS may lead to preterm birth and small-for-gestational-age neonates,which changes patient counseling and leads to arranging specialized obstetrical care for these patients with OHSS.

关键词： Obstetric labor,premature Hypertension Frozen cycle fresh cycle

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