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Therapeutic challenges in metastatic follicular thyroid cancer occurring in pregnancy:A case report

World Journal of Obstetrics and Gynecology 2022年第3期11卷 33-39页

作者： Claudio Spinelli Beatrice Sanna Marco Ghionzoli Elisabetta Micelli Division of Pediatric and Adolescent Surgery Department of SurgicalMedicalMolecular Pathology and of the Critic AreaUniversity of PisaPisa 56100Italy Division of Gynecology and Obstetrics University of PisaPisa 56100Italy

BACKGROUND Hormones could play a role in the evolution of follicular thyroid cancer(FTC)for which we discuss an unusual presentation of FTC occurring during pregnancy.CASE SUMMARY A pregnant woman was admitted with FTC metastasis resulting in a gluteal mass.Preoperative abdominal computed tomography revealed liver metastasis for which the patient underwent total thyroidectomy and liver resection,oral radioiodine therapy and radiotherapy,followed by embolization of the pelvic mass.The patient died of cerebral hemorrhage 16 mo after the initial diagnosis.CONCLUSION Human chorionic gonadotropin and estrogen stimulation might have a role in cancer growth,especially during pregnancy.FTC management aims to stop disease progression and overcome hormonal imbalances after thyroidectomy thus reducing fetal complications.It is still under debate whether it is possible to combine optimal timing for treatment to ensure the best possible outcome with reduction of fetal complications and risk of cancer growth.

关键词： Gluteal pain follicular thyroid cancer Metastases Pregnancy Unusual presentation Case report

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Unusual Scalp Process Revealing a thyroid cancer: “Illustrative Case”

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Open Journal of Modern Neurosurgery 2023年第4期13卷 183-188页

作者： Ibrahim Dao Ademayali Franck Auguste Hermann Ido Abdoulaye Adamou Babana Abdoulaye Sanou Ousmane Ouattara Souleymane Ouattara Astride Somda Haoua Alzouma Sylvain Delwendé Zabsonré Abel Kabré Department of Neurosurgery Hospital Souro Sanou Higher institute of health sciences Nazi Boni University Bobo Dioulasso Burkina Faso Department of Pathology Hospital Tengandogo Joseph Ki-Zerbo University Ouagadougou Burkina Faso Department of Neurosurgery Maradi Reference Hospital Dan Dikko Dan Koulodo University Maradi Niger Department of Neurosurgery Hospital Yalgado Ouédraogo Joseph Ki-Zerbo University Ouagadougou Burkina Faso Department of Neurosurgery Niamey National Hospital Abdou Moumouni University Niamey Niger

Background: thyroid cancers commonly display slow evolution with local and or regional extension. The classic presentation is a painless nodule of the thyroid region in a euthyroid patient. Sometimes, the nodule is discovered only on ultrasonography. Cervical lymph node is often seen in papillary thyroid cancer due to their propensity to invade lymph node. This means that follicular thyroid cancers are more insidious. Observation: We report a painless slow-growing lesion of the scalp revealing a skull metastasis of thyroid cancer. Despite catastrophic intraoperative bleeding, a total removal was achieved. Lessons: Thus, in addition to local and regional control in the management of thyroid cancers, distant metastasis should be surgically removed to provide the best chance to prolong the patient’s survival. Moreover, neurosurgeon must be prepared to deal with massive bleeding in skull metastasis of thyroid cancer.

关键词： thyroid cancer follicular thyroid cancer Papillary thyroid cancer Subcutaneous Metastasis Surgery

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Pattern of thyroid cancer at King Abdulaziz University Hospital, Jeddah: A 10-Year Retrospective Study

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Open Journal of Endocrine and Metabolic Diseases 2016年第3期6卷 121-125页

作者： Amani Alhozali Aisha Al-Ghamdi Jawaher Alahmadi Department of Medicine King Abdulaziz University Hospital Jeddah Saudi Arabia

Background and objective: thyroid cancer is the most common endocrine malignancy. This report aims to describe the pattern of thyroid cancer presentations at King Abdulaziz University Hospital, Jeddah. Methods: This was a retrospect chart review of all thyroid cancer cases diagnosed between 2001 and 2010 at King Abdulaziz University Hospital, Jeddah. We documented patients’ demographic and clinical data, including age at diagnosis, tumor type and size, extrathyroidal extension, and metastasis. Results: A total of 114 thyroid cancer cases were diagnosed from 2001 through 2010. Females comprise the majority of cases (female to male ratio of 4:1). The mean ages of patients diagnosed with different thyroid cancers were: papillary thyroid cancer, 39.6 years;follicular thyroid cancer, 43.2 years;medullary thyroid cancer, 55.8 years;and anaplastic thyroid cancer, 46.0 years. Papillary thyroid cancer was diagnosed in 88 cases (77%), follicular thyroid cancer in 19 cases (17%), medullary thyroid cancer in 5 cases (4%), and anaplastic thyroid cancer in 2 cases (2%). Conclusion: thyroid cancers are more common among females. The disease is diagnosed at a relatively young age among our patients (40 years). Papillary thyroid cancer is the most common type of thyroid cancer.

关键词： Anaplastic thyroid cancer follicular thyroid cancer Medullary thyroid cancer Papillary thyroid cancer Endocrine Malignancy

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