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Adult focalβ-cell nesidioblastosis:A case report

World Journal of Clinical Cases 2023年第1期11卷 150-156页

作者： Kui Tu Li-Jin Zhao Jin Gu Department of General Surgery Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND nesidioblastosis usually refers to a series of clinical manifestations caused by the proliferation ofβ-cells in pancreatic islets,and these clinical manifestations are hyperinsulinemia and persistent *** to the size of the lesion,nesidioblastosis is divided into focal nesidioblastosis,diffuse nesidioblastosis and atypical nesidioblastosis,and its pathogenesis is still *** is mainly seen in infants and rarely reported in adults,especially focal nesidioblastosis,which is difficult to distinguish from *** SUMMARY We report a case of adult focalβ-cell nesidioblastosis in which the preoperative diagnosis was *** patient was a 48-year-old male who suffered from repeated morning and fasting palpitations,sweating,and severe disturbance of consciousness for 5 *** blood glucose was found to be as low as 1.79 mmol/L during an ***,abdominal computed tomography showed no *** resonance imaging and endoscopic ultrasonography demonstrated a nodular mass in the head of the pancreas,combined with hyperinsulinemia and high serum *** patient was diagnosed with insulinoma and underwent Beger surgery;however,the postoperative pathological results showed *** Although surgical resection is the preferred option for nesidioblastosis,some cases can be treated *** order to increase clinicians’understanding of nesidioblastosis,it is necessary to review the pathogenesis,diagnosis and treatment of this disease.

关键词： focal nesidioblastosis Hyperinsulinemia Persistent hypoglycemia Case report

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