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DEVELOPING LAW OF WATER-CONDUCTING fissure ZONE AND STRESS VARIATION

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中国有色金属学会会刊：英文版 1995年第4期5卷 18-21页

作者： Xu Guoyuan Gu Desheng Chen Shouru(Department of Resources Exploitation Engineering,Central South University of Technology,Changsha 410083) Central South Univ of Technology Changsha China

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关键词： backfilling method numerical simulation stress state water-condlucting fissure zone

Application of three-dimensional discrete element face-to-face contact model with fissure water pressure to stability analysis of landslide in Panluo iron mine

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Science China(Technological Sciences) 2005年第z1期48卷 146-156页

作者： ZHANG Lei1,2, WEI Zuoan1, LIU Xiaoyu1 & LI Shihai1 1.Institute of Mechanics, Chinese Academy of Sciences, Beijing 100080, China 2.Graduate School, Chinese Academy of Sciences, Beijing 100060, China Chinese Acad Sci Inst Mech Beijing 100080 Peoples R China Chinese Acad Sci Grad Sch Beijing 100060 Peoples R China

Three-dimensional discrete element face-to-face contact model with fissure water pressure is established in this paper and the model is used to simulate three-stage process of landslide under fissure water pressure in the opencast mine, according to the actual state of landslide in Panluo iron mine where landslide happened in 1990 and was fathered in 1999. The calculation results show that fissure water pressure on the sliding surface is the main reason causing landslide and the local soft interlayer weakens the stability of slope. If the discrete element method adopts the same assumption as the limit equilibrium method, the results of two methods are in good agreement; while if the assumption is not adopted in the discrete element method, the critical φ numerically calculated is less than the one calculated by use of the limit equilibrium method for the sameC. Thus, from an engineering point of view, the result from the discrete element model simulation is safer and has more widely application since the discrete element model takes into account the effect of rock mass structures.

关键词： face-to-facecontactmodel, fissure water pressure, three-dimensional discrete element method,landslide.

Quality of compounded topical 2% diltiazem hydrochloride formulations for anal fissure

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World Journal of Gastroenterology 2013年第34期19卷 5645-5650页

作者： Monil Shah Laura Sandler Vishwas Rai Charu Sharma Lakshmi Raghavan Ventrus Biosciences Inc. DermPathe Pharmaceuticals

AIM:To investigate the quality of topical 2%diltiazem formulations extemporaneously compounded by retail pharmacies openly offering drug-compounding ***:A participating healthcare professional wrote 12 prescriptions for compounded 2%diltiazem cream,with 2 refills allowed per *** 12sets of prescriptions were filled,at intervals of 1-2 wk between refills,at 12 different independent retail pharmacies that openly offer drug-compounding services in a major metropolitan *** 36 resultant preparations,provided as jars or tubes,were shipped,as soon as each was filled,at ambient temperature to the study core laboratory for high-performance liquid chromatography(HPLC)analysis,within 10 d of *** the HPLC analysis,8 different samples of the topical diltiazem,each approximately 1 g in weight,were taken from prespecified locations within each *** initiate the HPLC analysis,each sample was transferredto a 100 mL volumetric flask,to which methanol was *** HPLC analysis was conducted in accordance with the laboratory-validated method for diltiazem in cream,ointment,and gel *** main outcome measures were potency(percentage of label claim)and content uniformity of the compounded topical 2%diltiazem ***:Of the 36 prescriptions filled,30 were packaged in jars and 6 were packaged as *** prescriptions were specifically for cream formulations,but6 of the 12 pharmacies compounded 2%diltiazem as an ointment;for another pharmacy,which had inadequate labeling,the dosage form was *** United States Pharmacopoeia(USP)standard for potency is 90%-115%of label *** the 36 preparations,5(13.89%)were suprapotent and 13(36.11%)were *** suprapotent prescriptions ranged in potency from 117.2%to 128.5%of label claim,and the subpotent prescriptions ranged in potency from34.8%to 89.8%of label ***(38.9%)preparations lacked content uniformity according to the USP standard of 90%-110%pote

关键词： Anal fissure Pharmacy compounding Topical diltiazem Formulation potency Content uniformity

Numerical simulation and damage analysis of fissure field evolution law in a single coal seam mining

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International Journal of Mining Science and Technology 2012年第6期22卷 853-856页

作者： Feng Gao Xingguang Liu Chaofeng Ge Hongmei Cheng State Key Laboratory of Geomechanics and Deep Underground Engineering China University of Mining & Technology School of Mechanics and Civil Engineering China University of Mining & Technology

Based on the different deformation and failure laws of coal and rock materials under tensile or compressive loads,the damage variable was defined to divide three phases from the damage and rupture point of view in order to reveal the fissured field evolution characteristics and spatial distribution of coal and rock in the single coal seam mining with low permeability and rich *** to the corresponding damage constitutive equations,the secondary development of the finite element program was *** fissures field evolution law of a coal mine with single coal seam mining was calculated and analyzed by this new program and the distribution areas and failure degree of the surrounding coal and rock structures with damage,fissure or rupture are given on the condition of *** paper provides a scientific basis for quantitative research and evaluation of the safe simultaneous production of coal and gas.

关键词： Single coal seam Damage fissure Rupture Finite element

IGCP 641 Project:Mechanisms,Monitoring and Modeling Earth fissure Generation and Fault Activation due to Subsurface Fluid Exploitation

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Acta Geologica Sinica(English Edition) 2019年第S01期93卷 165-168页

作者： YE Shujun Dora CARREoN-FREYRE Pietro TEATINI Devin GALLOWAY Nanjing University Nanjing 210023China Universidad Nacional Autonoma de Mexico Queretaro 76230Mexico Padova University Padova 35131Italy United States Geological Survey IndianapolisIN 46278USA

Ground ruptures(fractures,earth fissures and reactivation of pre-existing surface faults)caused by extraction of fluids from the subsurface have been observed in hundreds of sedimentary basins worldwide,mainly in semi... 详细信息

关键词： mechanisms monitoring modeling earth fissure subsurface fluid exploitation

The analyses focusing on formation mechanism of Nanzhangzhuang ground fissure in Hengshui City,China

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Journal of Groundwater Science and Engineering 2018年第1期6卷 31-39页

作者： QI Jian-feng HE Fang WANG Cheng-zhen Hebei GEO University Shijiazhuang 050031China Hebei Provincial Key Laboratory of Sustained Utilization and Development of Water Resources Shijiazhuang 050031China

The paper focuses on the formation of Nanzhangzhuang ground fissure through emphatically analysing factors including the intersection fault dislocation,the deep ground-water over-exploitation together with the landform and lithology *** of the ground fissure are explained in detail after describing the geological setting in the study *** paper also provides dynamic mode of the ground fissure formation via force analysis of the soil body unit at ground *** can be drawn that the stress state of soil bodies changed with the activities of two intersection faults,namely Hengshui fault and Hubei *** addition,the stress fields control the development of ground *** deep groundwater in Hengshui area dropped considerably in recent years,to be precise,the water elevation of deep groundwater dropped from -26 m to -94 m by 2010 at the centre of groundwater *** over-exploitation of deep groundwater in Hengshui area enlarged the ground *** data concerning shallow borehole show that the vertical lithology mainly consists of silt,silty clay and silty sandy soil,which all belong to the middle-compressed *** lateral extension of the soil bodies occur with pumping and tectonic creep,and the clay layers on both sides of the cracks can stay *** the ground fissure came visible.

关键词： Ground fissure Mechanism analysis Intersection faults Deep ground water Landform and lithology

Innovations in chronic anal fissure treatment:A systematic review

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World Journal of Gastrointestinal Surgery 2010年第7期2卷 231-241页

作者： Aaron Poh Kok-Yang Tan Francis Seow-Choen Department of Surgery Khoo Teck Puat HospitalSingapore 768828Singapore Seow-Choen Colorectal Centre Singapore 228510Singapore

A chronic anal fissure is a common perianal *** review aims to evaluate both existing and new therapies in the treatment of chronic *** therapies such as glyceryl trinitrate(GTN),Diltiazem ointment and Botulinum toxin provide a relatively non-invasive option,but with higher recurrence *** sphincterotomy remains the gold standard for *** dilatation has no role in *** therapies include perineal support devices,Gonyautoxin injection,fissurectomy,fissurotomy,sphincterolysis,and flap *** research is required comparing these new therapies with existing established *** paper recommends initial pharmacological therapy with GTN or Diltiazem ointment with Botulinum toxin as a possible second line pharmacological *** support may offer a new dimension in improving healing *** sphincterotomy should be offered if pharmacological therapy *** therapies are not suitable as first line treatments,though they can be considered if conventional treatment fails.

关键词： Anal fissure Innovative therapy Glyceryl trinitrate Lateral sphincterotomy Diltiazem Botulinum toxin Perineal support device

Identifying the best therapy for chronic anal fissure

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2011年第2期2卷 9-16页

作者： Mariusz H Madalinski NHS Lothian-University Hospitals Division Edinburgh EH4 2XUUnited Kingdom

Chronic anal fissure(CAF)is a painful tear or crack which occurs in the *** optimal algorithm of therapy for CAF is still *** internal sphincterotomy(LIS)is a surgical treatment,considered as the'gold standard'therapy for *** relieves CAF symptoms with a high rate of *** sphincterotomy(CS)with nitrates,calcium blockers or botulinum toxin(BTX)is safe,with the rapid relief of pain,mild sideeffects and no risk of surgery or anesthesia,but is a statistically less effective therapy for CAF than *** article considers if aggressive treatment should only be offered to patients who fail pharmacological *** of anal fissure etiology,epidemiology and pathophysiology are considered with their meaning for further management of CAF.A molecular model of chemical interdependence significant for the chemistry of CAF healing is *** application may influence the development of optimal therapy for *** is currently considered the most effective type of CS and discussion in this article scrutinizes this method *** the effectiveness of BTXvs LIS has been discussed,the essential focus of the article concerns identifying the best therapy application for anal *** are presented which may help us to predict CAF *** provide rationale for the expansion of the CAF therapy *** and economic factors are also considered in *** long as the patient is willing to accept the potential risk of fecal incontinence,we have grounds for the'gold standard'(LIS)as the first-line treatment for *** author concludes that,when the diagnosis of the anal fissure is established,CS should be considered for both ethical and economic *** is convinced that a greater understanding and recognition of benign anal disorders by the GP and a proactive involvement at the point of initial diagnosis would facilitate the consideration of CS at an earlier,more practical stage with improved outc

关键词： Anal fissure Benign anal diseases Chemical sphincterotomy Botulinum toxin Lateral internal sphincterotomy fissurectomy Ethics Teaching

Treatment of a densely fused fissure during thoracoscopic right middle lobectomy

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Open Journal of Pediatrics 2013年第2期3卷 105-107页

作者： Hiroyuki Koga Kenji Suzuki Tadaharu Okazaki Kinya Nishimura Geoffrey J. Lane Atsuyuki Yamataka Department of Anesthesiology Juntendo University School of Medicine Tokyo Japan Department of Pediatric General and Urogenital Surgery Juntendo University School of Medicine Tokyo Japan Department of Thoracic General Surgery Juntendo University School of Medicine Tokyo Japan

Aim: To report a case of fused fissure between the right upper and middle lobes that we treated using a surgical stapler rather than a Ligasure device for the benefit of creating a better division between the right upper and middle lobes and to effectively seal the lung parenchyma. Case: A 2-year-old girl with congenital cystic adenomatoid malformation of the right middle lobe (RML) was referred to our institution for further management after a series of infections. The vein of the RML, which drains into the superior pulmonary vein, was isolated and divided using endoclips. The bronchus was then exposed and divided using endo-clips. The arteries of the RML could be identified and ligated, allowing a line demarcating the major fissure to be identified and dissected. A stapler device was then used to seal the lung parenchyma and create a division between the right upper and middle lobes. She is currently well after follow-up of 16 months, with no episodes of respiratory distress or recurrence of symptoms. Conclusion: Our technique for dividing the pulmonary vein, then the bronchus, then the pulmonary artery and finally the fused fissure is safe and could be applied whenever fused fissures are encountered during thoracoscopic pulmonary lobectomy.

关键词： Thoracoscopic Surgery Pulmonary Lobectomy Fused fissure Surgical Stapler