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Therapeutic Effects of an Alpha-Casozepine and White fish muscle Hydrolyzed Complementary Feed on Canine Separation-Related Disorders and Quality of Life of Dogs and Their Pet Owners

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Open Journal of Veterinary Medicine 2023年第6期13卷 68-81页

作者： Gaëlle Porcheron Marie Bodet Katell Poiron Julie Brault Nicolas Massal Olivier Roy Oscar Fantini Cebiphar Fondettes France Clinique Vétérinaire de la Victoire Tours France Clinique Vétérinaire LESVET Lesneven France Clinique Vétérinaire du Gabereau Chateuneuf-sur-Loire France Clinique Vétérinaire de la Paix Pau France Vetoquinol SA Paris France

Background: Separation-related disorders are prevalent in dogs and can result in problem behaviours such as inappropriate elimination, destructive behaviour, and distress vocalizations which occur when an owner is absent or perceived as absent. Numerous natural products are marketed for managing anxiety in dogs;however, few, if any, of these products have documented evidence of efficacy in veterinary behaviour. Purpose: This open, multicentric clinical trial aimed to assess the efficacy of a new supplement containing alpha-casozepine and fish muscle hydrolysate on the separation-related problem in dogs and the impact on the quality of life of dogs and their pet owners. Material and Methods: Fifty-one dogs with clinical signs compatible with separation-related problems were included. The dogs were treated with a complementary feed (Zylkene Plus, Vetoquinol, France) for 30 days. Separation-related behaviour assessment (SRP), emotional disorders assessment (EDED) and the quality of life (QoL) of the pets and their pet owner were assessed at baseline and the end of the study by the veterinarians. In addition, owners were asked to rate their dog’s SRP weekly after enrolment using the same questionnaire that the veterinarian used at the beginning of the study. Results: There was a statistically significant improvement in the SRP, EDED, and QoL scores (P Conclusion: The results of this study support the hypothesis that the combination of alpha-casozepine and fish muscle hydrolysate is a promising and effective option to reduce the frequency and severity of separation-related behaviour in dogs and improve the quality of dogs and their owners.

关键词： Alpha-Casozepine fish muscle hydrolysate Canine Separation-Related Disorders Dogs

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