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Efficiently Writing Bragg Grating in High-Birefringence Elliptical Microfiber for Label-Free Immunosensing with Temperature Compensation

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Advanced fiber Materials 2021年第5期3卷 321-330页

作者： Peng Xiao Zhiyuan Xu Deming Hu Lili Liang Lipeng Sun Jie Li Yang Ran Bai‑Ou Guan Guangdong Provincial Key Laboratory of optical fiber Sensing and Communications Institute of Photonics TechnologyJinan UniversityGuangzhou 510632China Ji Hua Laboratory Foshan 528300China Institute of Information Technology Handan UniversityHandan 056005China

Immunosensor is a powerful tool in healthcare and clinic,food and drug industry,and environmental ***-free fiber-optic immunosensors have shown a myriad of advantages,such as high sensitivity,anti-electromagnetic interference,and afield measurement via the fiber ***,the fiber-optic based sensor may bear the temperature cross-talk,especially under the warming condition for bio-activating the immune *** this study,we proposed a highly birefringent microfiber Bragg grating for immunosensing with the *** birefringent microfiber was drawn from the elliptical cladding multimode fiber that was ablated by the CO2 *** considerably large energy overlap region offered by the original multimode fiber favored the efficient inscription of FBG with high *** dual reso-nances derived by the orthogonal polarization states presented similar temperature responsivities but significantly different ambient refractive index sensitivities,allowing the temperature-compensational RI *** human immunoglobulin G(IgG)molecules were anchored on the surface of the microfiber grating probe by the covalent functionalization technique to enable the specific detection of the anti-IgG *** proposed method promises a high-efficiency and low-cost design for the microfiber Bragg grating-based biosensor without being subjected to the temperature cross-sensitivity.

关键词： fiber-optic biosensors Microfiber fiber Bragg grating Birefringence Temperature compensation Immunosensing

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