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Diagnostic challenges from conflicting results of tests and imaging

World Journal of Clinical Cases 2024年第24期12卷 5448-5451页

作者： Run Yu Division of Endocrinology Diabetesand MetabolismUCLA David Geffen School of MedicineLos AngelesCA 90095United States

Accurate diagnosis is the foundation of clinical care but accurate diagnosis is not easily reached in some *** rare instances,even a sophisticated multidisciplinary team at an academic medical center cannot reliably reach an accurate diagnosis after extensive testing and imaging,and has to wait until histological diagnosis or even autopsy results are *** underlying reason of challenging diagnoses is mostly conflicting data from history,tests,and imaging that point to different *** this issue of World Journal of Clinical Cases,Huffaker et al reported such a challenging case of a tricuspid mass in a patient with Li-Fraumeni *** case by Huffaker et al powerfully illustrates the occasional diagnostic challenges inherent in our current diagnostic approach and the current *** should realize that in rare situations,agnosticism in diagnosis is unavoidable but a treatment has to be initiated so long as the principle of primum non nocere is upheld.

关键词： Li-Fraumeni syndrome Cardiac mass Thrombus Challenging diagnosis Histological diagnosis false positive results

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Current dilemma in photocatalytic CO_(2) reduction:real solar fuel production or false positive outcomings?

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碳中和(英文) 2022年第1期1卷 491-506页

作者： Kai Zhang Qi Gao Cuiping Xu Dawei Zhao Qibin Zhu Zhonghui Zhu Jin Wang Cong Liu Haitao Yu Chen Sun Xianglei Liu Yimin Xuan College of Energy and Power Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China Key Laboratory of Thermal Management and Energy Utilization of Aviation Vehicles Ministry of Industry and Information TechnologyNanjing 210016JiangsuChina

Solar driven carbon dioxide(CO_(2))recycling into hydrocarbon fuels using semiconductor photocatalysts offers an ideal energy conversion pathway to solve both the energy crisis and environmental degradation ***,the ubiquitous presence of carbonaceous contaminants in photocatalytic CO_(2) reduction system and the inferior yields of hydrocarbon fuels raise serious concerns about the reliability of the reported experimental *** in this perspective,we focus on the accurate assessment of the CO_(2) reduction products,systemically discuss the possible sources of errors in the product quantification,elaborate the common mistakes spread in the analysis of reaction products obtained in 13CO_(2) labelling experiments,and further propose reliable protocols for reporting the results of these isotopic tracing ***,the challenges and cautions in the precise measurement of O_(2) evolution rate are also depicted,and the amplification of the concentration of O_(2) in photoreactors well above the limit of detection is still demonstrated to be the most effective solution to this troublesome *** hope the viewpoints raised in this paper will help to assessment the reliability of the reported data in future,and also benefit the beginners that intend to dive in the photocatalytic CO_(2) reduction area.

关键词： Artificial photosynthesis Solar fuels Photocatalytic CO_(2)reduction Pitfalls Isotopic tracing false positive results

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