检索结果-南通市图书馆

facile synthesis and antitumor activity of novel 2-trifluoromethylthieno[2,3-d]pyrimidine derivatives

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2014年第7期25卷 1006-1010页

作者： Xin-Jian Song Ping Yang Hui Gao Yan Wang Xing-Gao Dong Xiao-Hong Tan Key Laboratory of Biologic Resources Protection and Utilization of Hubei Province Hubei Minzu University College of Forestry and Horticulture Hubei Minzu University

A series of novel 2-trifluoromethylthieno[2,3-d]pyrimidine derivatives were synthesized by a facile three-step procedure that afforded advantages of mild reaction conditions, simple protocol and good yields. The structures of the final compounds were confirmed by 1R, NMR, El-MS, elemental analysis, and X-ray diffraction. Preliminary bioassay results showed that some of the analogs exhibit excellent antitumor activity against MCF-7 and HepG2, especially compounds 3a, 3b, 3e and 3h exhibited higher activity than the positive control gefitinib.

关键词： Thieno[2,3-d]pyrimidine Gewald reaction Trifluoromethyl facile synthesis Anritumor activity

facile synthesis of tin oxide nanocrystals and their photocatalytic activity

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2014年第6期24卷 1813-1818页

作者：贾志谦孙慧杰王妍甄甜丽常青北京师范大学化学学院北京100875 装甲兵工程学院再制造技术重点实验室北京100072

Tin oxide nanociystals with diameters smaller than 10 nm were synthesized using Na2SnO3 and CO2 as reactants and cetyltrimethylammonium bromide（CTAB） as stabilizer under mild *** a mild acidic gas,CO2 is favorable for the accurate adjustment of pH value of Na2SnO3 *** salt is stable,cheap and easy in *** effects of Na2SnO3concentration,CTAB concentration,aging temperature,and aging time on the nanociystals were *** was found that,with the increasing Na2SnO3 concentration,aging temperature and aging time,SnO2 nanociystals size *** formation of SnO2nanociystals can be interpreted by electrostatic-interaction ***2 nanociystals show high photocatalytic activities in the degradation of Rhodamine B *** catalytic activity of small nanocrystals is higher than that of large ones.

关键词： tin oxide nanocrystals facile synthesis photocatalytic activity

Layer-controlled Pt-Ni porous nanobowls with enhanced electrocatalytic performance

在线全文

学校读者我要写书评

暂无评论

Nano Research 2017年第1期10卷 187-198页

作者： Hongsheng Fan Ming Cheng Zhenlei Wang Rongming Wang Department of Physics Beihang University Beijing 100191 China School of Mathematics and Physics University of Science and Technology Beijing Beijing 100083 China

Hollow and porous Pt-based nanomaterials are promising catalysts with applications in many sustainable energy technologies such as fuel cells. Economical and green synthetic routes are highly desirable. Here, we report a facile approach to prepare double- and single-layered Pt-Ni nanobowls （DLNBs and SLNBs） with porous shells. Microstructural analysis revealed that the shells were constructed of alloyed Pt-Ni nanocrystals and small amounts of Ni compounds. X-ray photoelectron spectra showed that their Pt 4f binding energies shifted in the negative direction compared to those of the commercial Pt/C catalyst. Furthermore, the DLNBs contained greater contents of oxidized Ni species than the SLNBs. The layer-controlled growth processes were confirmed by microscopy, and a formation mechanism was proposed based on the assistance of citrate and poly（vinylpyrrolidone）（PVP）. For the methanol oxidation reaction, the DLNBs and SLNBs exhibited 2.9 and 2.5 times higher mass activities than that of the commercial Pt/C catalyst, respectively. The activity enhancements were attributed to electronic effects and a bifunctional mechanism. Chronoamperometry and prolonged cyclic voltammetry indicated that the Pt-Ni bowl-like structures had better electrochemical properties and structural stability than the commercial Pt/C catalyst, thus making the Pt-Ni nanobowls excellent electrocatalysts for use in direct methanol fuel cells.

关键词： Pt-Ni nanobowls facile synthesis sodium citrate poly(vinylpyrrolidone)(PVP) electrocatalysis

Single-step flash-heat synthesis of red phosphorus/ graphene flame-retardant composite as flexible anodes for sodium-ion batteries

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2018年第7期11卷 3780-3790页

作者： Yihang Liu Anyi Zhang Chenfei Shen Qingzhou Liu Jiansong Cai Xuan Cao Chongwu Zhou Ming Hsieh Department of Electrical Engineering University of Southern California Los Angeles California 90089 USA Mork Family Department of Chemical Engineering and Materials Science University of Southern California Los Angeles California 90089 USA

Red phosphorus （RP） has attracted considerable attention as the anode for high-performance Na-ion batteries, owing to its low cost and high theoretical specific capacity of -2,600 mAh/g. In this study, a facile single-step flash-heat treatment was developed to achieve the reduction of graphene oxide （GO） and the simultaneous deposition of RP onto the reduced graphene oxide （rGO） sheets. The resulting RP/rGO composite was shown to be a promising candidate for overcoming the issues associated with the poor electronic conductivity and large volume variation of RP during cycling. The RP/rGO flexible film anode delivered an average capacity of 1,625 mAh/g during 200 cycles at a charge/ discharge current density of 1 A/g. Average charge capacities of 1,786, 1,597, 1,324, and 679 mAh/g at 1, 2, 4, and 6 A/g current densities were obtained in the rate capability tests. Moreover, owing to the RP component, the RP/rGO film presented superior flame retardancy compared to an rGO film. This work thus introduces a highly accessible synthesis method to prepare flexible and safe RP anodes with superior electrochemical performance toward Na-ion storage.

关键词： sodium-ion batteries red phosphorus facile synthesis flexible flame-retardant reduced graphene oxide

Efficient antimicrobial properties of layered double hydroxide assembled with transition metals via a facile preparation method

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2020年第6期31卷 1511-1515页

作者： Mengxue Li Li Li Sijie Lin College of Environmental Science and Engineering Shanghai Institute of Pollution Control and Ecological SecurityKey Laboratory of Yangtze River Water EnvironmentTongji UniversityShanghai 200092China Australian Institute of Bioengineering and Nanotechnology The University of QueenslandBrisbaneQLD 4072Australia

Mg2+in MgAl-layered double hydroxides nanoparticles was substituted with different divalent transition metal ions(MAl-LDHs,M:Mg2+,Cu2+,Ni2+,Co2+,and Mn2+)via a facile method to be used as antibacterial *** phase structural and morphological characterizations of MAl-LDHs were investigated by XRD,FTIR spectroscopy and *** results have shown that all of MAl-LDHs had typical layered structures except MnAl-LDH which contained Mn304 *** morphology of MnAl-LDH with ellipsoids,spherical and rod-like structure and CuAl-LDH with rod-like shape ***50(the concentrations providing 50%antibacterial activity)values of CuAl-LDH,NiAl-LDH,CoAl-LDH,and MnAlLDH in broth dilution tests were^800-1500μg/*** of CuAl-LDH,CoAl-LDH,and MnAl-LDH with>10 mm inhibition zone in disk diffusion tests were^150-300μg/*** mechanism of MAl-LDHs may be attributed to the synergistic factors including effected surroundings,surface interactions,morphology of particles,ROS and metal *** results indicate a facile method to synthesis LDHs based effective antibacterial agents with the potential application in the area of water treatment and antibacterial coating.

关键词： Layered double hydroxides Transition metals facile synthesis Antibacterial activity Synergistic mechanism

Upconversion nanoparticles@AgBiS_(2) core-shell nanoparticles with cancer-cell-specific cytotoxicity for combined photothermal and photodynamic therapy of cancers

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2022年第11期7卷 71-80页

作者： Zhaoyou Chu Tian Tian Zhenchao Tao Juan Yang Benjin Chen Hao Chen Wanni Wang Peiqun Yin Xiaoping Xia Hua Wang Haisheng Qian School of Biomedical Engineering School of Basic Medical SciencesAnhui Provincial Institute of Translational MedicineAnhui Medical UniversityHefeiAnhui230032PR China Department of Oncology The First Affiliated Hospital of Anhui Medical UniversityAnhui Medical UniversityHefeiAnhui230032PR China Department of Radiation Oncology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui230031China Department of Obstetrics and Gynecology Children’s Hospital of Anhui Medical UniversityAnhui Provincial Children’s HospitalHefeiAnhui230051PR China

UCNPs@AgBiS_(2) core-shell nanoparticles that AgBiS_(2) coated on the surface of upconversion nanoparticles (UCNPs) was successfully prepared through an ion exchange reaction. The photothermal conversion efficiency of AgBiS_(2) can be improved from 14.7% to 45% due to the cross relaxation between Nd ions and AgBiS_(2). The doping concentration of Nd ions played a critical role in the production of reactive oxygen species (ROS) and enhanced the photothermal conversion efficiency. The NaYF4:Yb/Er/Nd@NaYF4:Nd nanoparticles endows strong upcon-version emissions when the doped concentration of Nd ions is 1% in the inner core, which excites the AgBiS_(2) shell to produce ROS for photodynamic therapy (PDT) of cancer cells. As a result, the as-prepared NaYF4:Yb/Er/ Nd@NaYF4:Nd@AgBiS_(2) core-shell nanoparticles showed combined photothermal/photodynamic therapy (PTT/ PDT) against malignant tumors. This work provides an alternative near-infrared light-active multimodal nano-structures for applications such as fighting against cancers.

关键词： Upconversion nanoparticles Core-shell nanoparticles Photothermal conversion facile synthesis Photodynamic therapy

One-pot synthesis of Fe_(x)O_(y)nanoparticles embedded within N-doped carbon layers as highly efficient and selective catalysts for the hydrogenation of nitroarenes

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2023年第6期34卷 323-328页

作者： Xiuzheng Zhuang Ke Jin Qi Zhang Jianguo Liu Xinghua Zhang Hao Zhan Longlong Ma Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education School of Energy and EnvironmentSoutheast UniversityNanjing 210096China Key Laboratory of Renewable Energy Guangzhou Institute of Energy ConversionChinese Academy of SciencesGuangzhou 510640China School of Energy Science and Engineering Central South UniversityChangsha 410083China

Inhibiting the side reactions while promoting hydrogenation are the main target for the production of functional anilines from nitroarenes;consequently,the preparation of an ideal catalyst to improve chemical selectivity is one of the hot *** this work,we provided an easy-to-prepare catalyst with Ndoped carbon layers,where the Fe_(x)O_(y)nanoparticles were encapsulated and distributed *** structural features of catalyst were characterized by several techniques,and the selected catalyst was next applied to the hydrogenation of nitrobenzene under varied conditions,involving temperature,holding period and H2 ***,we conducted the synthesis of more than 16 substrates for the corresponding anilines with varied functional *** hydrogenation protocol to gram-scale synthesis as well as lifecycle performance were also demonstrated in the batch reactor,together with the explanation of its catalytic ***,the present work provides an available preparation of simple but highly efficient catalysts for the production or aromatic amines,which will be benefit for the sustainable development of this field in near future.

关键词： facile synthesis Iron-based catalyst Carbonaceous layers Nitroarenes reduction

High-refractive index acrylate polymers for applications in nanoimprint lithography

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2020年第1期31卷 256-260页

作者： Yunhui Tang Stefano Cabrini Jun Nie Carlos Pina-Hernandez State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing 100029China The Molecular Foundry LBNLBerkeleyCA 94702United States aBeam Technologies Castro ValleyCA 94546United States

The development of polymeric optical materials with a higher refractive index,transparency in the visible spectrum region and easier processability is increasingly desirable for advanced optical applications such as microlenses,image sensors,and organic light-emitting *** acrylates have a low refractive index(around 1.50)which does not meet the high perfo rmance requirements of advanced optical *** this research,three novel acrylates were synthesized via a facile one-step approach and used to fabricate optical transparent *** of the polymers reveal good optical properties including high transparency(≥90%)in the visible spectrum region and high refractive index values(1.6363)at 550 ***,nanostructures of these acrylate polymers with various feature sizes including nanogratings and photonic crystals were successfully fabricated using nanoimprint *** results indicate that these acrylates can be used in a wide range of optical and optoelectronic devices where nanopatterned films with high refractive index and transparency are required.

关键词： High refractive index Acrylate facile synthesis Nanostructure Nanoimprint lithography

Syntheses, Crystal Structures, and Antitumor Activities of Two 2-Trifluoromethyl-5,6,7,8-tetrahydrobenzo[4,5]-thieno[2,3-d]pyrimidin-4-amine Derivatives

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2014年第12期33卷 1789-1795页

作者：聂瑶黄东海王发松但悠梦赵金顺宋新建 Key Laboratory of Biologic Resources Protection and Utilization of Hubei Province Hubei University for Nationalities School of Chemical and Environmental Engineering Hubei University for Nationalities

Two novel 2-trifluoromethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine derivatives were synthesized by nucleophilic substitution of two appropriate amines with 4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidine, which started from 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile, trifluoroacetic acid(TFA) and phosphorous oxychloride by one-pot procedure. Their structures were determined by single-crystal X-ray diffraction. Compound 1, N-(furan-2-ylmethyl)-2-trifluoromethyl-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4-amine, crystallizes in the monoclinic system, space group C2/c with a = 26.352(3), b = 7.5991(8), c = 17.1423(18) A, β = 114.667(2)°, V = 3119.5(6) A3 and Z = 8. Compound 2, N-(3-silatranylpropyl)-2-trifluoromethyl-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4-amine, crystallizes in the monoclinic system, space group P21/n with a = 13.4394(13), b = 8.9446(9), c = 18.9657(18) A, β = 101.9640(10)°, V = 2230.3(4) A3 and Z = 4. The preliminary bioassay indicated that compound 2 exhibits more potent antitumor activity against BCG-823 than 5-fluorouracil(5-FU).

关键词： thieno[2,3-d]pyrimidine facile synthesis trifluoromethyl antitumor activity