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2009国际暨第十届全国头颈肿瘤大会

作者： Lu Xuguang Cai Zhigang Yu Guangyan Peng Xin Huang Minxian Dept.Oral & Maxillofacial Surgery Peking University School & Hospital of Stomatology Beijing 100081

＜正＞Objective:To assess the long time follow-up nerve function and clinical value of great auricular nerve grafting in the treatment of facial palsy after *** and method:Fourteen patients with parotid tumors who were treated with great auricular nerve grafting after parotidectomy were followed up from 1998 to 2004（9 males and 5 females;age range 22～65 years）.Four were benign and ten were malignant *** of them were unilateral affected. Eleven cases of nerve grafting were done immediately after the tumor *** cases were done 6 months after tumor surgery and one case was 9 *** cases were affected in the facial nerve main trunk,four cases in the cervical division,one in the zygomatic branch and one in the zygomatic and temporal *** great auricular nerve in the same side of the tumor was harvested for nerve grafting except for both sides were used in one *** patients were followed up from half a year to 5 years,until they were recovered or no obvious recovery was observed in half a *** drugs and neuromuscular facial retraining were both given after ***-Brackmann grading scale,electroneurography were applied to evaluate the ***:Ten cases which were treated at the same time with tumor dissection recovered to HB gradeⅠtoⅡexcept for one patient recurred one year after operation All 10 patients were satisfied with the results.7 cases suffered from synkinesis in the tumor side.2 patients had no recovery in lifting *** showed the amplitudes in the grafting sides are all lower than the normal *** 1 of the 3 cases which were treated more than half a year later recovered to HB gradingⅡ,the other 2 had no recovery in facial nerve movement and electroneurography showed no ***:The great auricular nerve grafting is an effective method in the treatment of facial nerve defect in parotidectomy.A great part of facial nerve function will be preserved after

关键词： Parotid tumor facial palsy Great auricular nerve Nerve grafting

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Awareness of Hail Region Population about facial Nerve palsy (Seventh Cranial Nerve palsy)

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Neuroscience & Medicine 2022年第3期13卷 111-119页

作者： Ghorashy Eltayeb Yousif Turki Saud Alshammari Hamoud Abdelkarim Almarshadi College of Medicine University of Ha’il Ha’il Saudi Arabia Department of Pathology and Microbiology University of Kordofan El-Obeid Sudan

Background: facial nerve palsy (seventh cranial nerve palsy) is a common neurological problem. The etiology is not fully understood but it is thought to be due to injury or compression throughout the seventh cranial nerve course. The study aimed to evaluate the awareness of the Hail region population about facial nerve palsy, its risk factors, methods of treatment, and prognosis. Methodology: This cross-sectional descriptive study was conducted in the Hail region from March to June 2022. The study involved 224 participants in the age group 18 - 65 years and data was collected through Google self-administered questionnaire. Results: 65.2% of the participants were 18 - 25 years, 20.1% were 26 - 35 years and 14.7 were above 35 years. 91.9% think that exposure to cold air is the leading cause followed by viral infections (30.4%), stroke (27.6%), and genetic factors (13.8%). diabetes (8.5%), evil eye (7.1%), magic (4%), pregnancy (0.4%) and vitamins deficiency (0.4%). 92% of participants think that facial nerve palsy is not contagious and 8% have no clear idea. 89.7% think that facial nerve palsy is curable, 83.9% think that physiotherapy is the treatment of choice, 94.6% agree that early medical assessment is essential for good outcomes and 92.9 believe that avoidance of cold air is the best method of prevention. Conclusion and Recommendations: The majority of participants show poor awareness regarding the etiology and the preferable treatment of facial nerve palsy. Public medical education and further wider studies are highly recommended.

关键词： facial palsy Causes Treatment Hail Awareness

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Recovery from Bell’s palsy after treatment using uncultured umbilical cord-derived mesenchymal stem cells:A case report

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World Journal of Clinical Cases 2023年第12期11卷 2817-2824页

作者： Hyunjun Ahn Won-Ju Jung Sang Yeon Lee Kye-Ho Lee Stem Cell Treatment and Research Institute bio Beauty and Health CompanySeoul 04420South Korea Stem Cell Treatment 97.7 Beauty and Health ClinicSeoul 04420South Korea

BACKGROUND Bell’s palsy is an idiopathic facial palsy with an unknown cause,and 75%of patients heal ***,the other 25%of patients continue experiencing mild or severe disabilities,resulting in a reduced quality of ***,various treatment methods have been developed to treat this ***,there is controversy regarding their effectiveness,and new alternative treatments are *** SUMMARY The patient suffered from left-sided facial paralysis due to Bell’s palsy for 7 *** patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for *** follow-up for 32 mo,the paralysis was cured,and there was no *** Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell’s palsy who do not spontaneously recover.

关键词： Bell’s palsy facial palsy Umbilical cord-mesenchymal stem cells Allogenic Case report

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facial reanimation with interposition nerve graft or masseter nerve transfer:a comparative retrospective study

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Neural Regeneration Research 2022年第5期17卷 1125-1130页

作者： Wen-Jin Wang Wei-Dong Zhu Mathias Tremp Gang Chen Zhao-Yan Wang Hao Wu Wei Wang Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Otolaryngology Head and Neck Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases ShanghaiChina Ear Institute Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Plastic ReconstructiveAesthetic and HandsurgeryUniversity Hospital BaselBaselSwitzerland

Both interposition nerve grafts and masseter nerve transfers have been successfully used for facial reanimation after irreversible injuries to the cranial portion of the facial ***,no comparative study of these two procedures has yet been *** this two-site,twoarm,retrospective case review study,32 patients were *** these,17 patients(eight men and nine women,mean age 42.1 years)underwent interposition nerve graft after tumor extirpation or trauma between 2003 and 2006 in the Ear Institute,School of Medicine,Shanghai Jiao Tong University,China,and 15 patients(six men and nine women,mean age 40.6 years)underwent masseter-to-facial nerve transfer after tumor extirpation or trauma between November 2010 and February 2016 in Shanghai Ninth People's Hospital,*** patients achieved House-Brackmann III recovery after masseter nerve repair than interposition nerve graft repair(15/15 vs.12/17).The mean oral commissure excursion ratio was also higher in patients who underwent masseter nerve transfer than in patients subjected to an interposition nerve *** findings suggest that masseter nerve transfer results in strong oral commissure excursion,avoiding obvious synkinesis,while an interposition nerve graft provides better resting *** study was approved by the Institutional Ethics Committee,Shanghai Ninth People's Hospital,China(approval ***9 H-2019-T332-1)on December 12,2019.

关键词： facial palsy facial reanimation facial symmetry House-Brackmann score interposition masseter nerve nerve graft oral commissure excursion resting symmetry synkinesis

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Acupuncture and vitamin B_(12) injection for Bell's palsy:no high-quality evidence exists

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Neural Regeneration Research 2015年第5期10卷 808-813页

作者： Li-li Wang Ling Guan Peng-liang Hao Jin-long Du Meng-xue Zhang Department of Acupuncture and Moxibustion Chinese PLA General Hospital

OBJECTIVE： To assess the efficacy of acupuncture combined with vitamin B12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell＇s palsy. DATA RETRIEVAL： A computer-based online retrieval of Medline, Web of Science, CNKI, CBM databases until April 2014 was performed for relevant trials, using the key words ＂Bell＇s palsy or idiopathic facial palsy or facial palsy＂ and＂acupuncture or vitamin B12 or methylcobalamin＂. STUDY SELECTION： All randomized controlled trials that compared acupuncture with acupuncture combined with vitamin B12 in patients with Bell＇s palsy were included in the me- ta-analysis. The initial treatment lasted for at least 4 weeks. The outcomes of incomplete facial recovery were monitored. The scoring index varied and the definition of healing was consistent. The combined effect size was calculated by using relative risk （RR） with 95% confidence interval （C/） using the fixed effect model of Review Manager. MAIN OUTCOME MEASURES： Incomplete recovery rates were chosen as the primary outcome. RESULTS： Five studies involving 344 patients were included in the final analysis. Results showed that the incomplete recovery rate of Bell＇s palsy patients was 44.50% in the acupuncture combined with vitamin B12 group but 62.57% in the acupuncture alone group. The major acupoints were Taiyang （EX-HN5）, Jiache （ST6）, Dicang （ST4） and Sibai （ST2）. The combined effect size showed that acupuncture combined with vitamin B12 was better than acupuncture alone for the treatment of Belrs palsy （RR = 0.71, 95%CI： 0.58-0.87; P = 0.001）, this result held true when 8 patients lost to follow up in one study were included into the analyses （RR = 0.70, 95%CI： 0.58-0.86; P = 0.0005）. In the subgroup analyses, the therapeutic effect in patients of the electroacupuncture subgroup was better than in the non-electroacupuncture subgroup （P = 0.024）. There was no significant dif- ference in the incomplete recovery rate by subgroup analysis on dru

关键词： nerve regeneration brain injury facial palsy Bell's palsy comparison methodologicalquality therapy fixed effect model acupuncture incomplete recovery randomized controlled trials electroacupuncture NSFC grants neural regeneration

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Metaphysical Energy Therapy in the Treatment of Cranial Nerve Palsies with Special Reference to Bell’s palsy

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Journal of Biosciences and Medicines 2016年第10期4卷 77-84页

作者： C. V. Krishnaswami C. Ramesh B. Sampoornam A. Ganesan V. Rajan TAG VHS Diabetes Research Centre (A Unit of Voluntary Health Services Diabetes Department) Chennai India

Neuropathy, or nerve injury, is a severe and common impediment of diabetes. Studies evaluate that 50% of people with diabetes will develop neuropathy. Diabetic nerve injury is impairment of a single solitary nerve (also named mononeuropathy). Com- monly 2 cranial nerves Viz., cranial nerve VII and cranial nerve VI are involved in facial nerve palsies. The former one is called Bell’s palsy and is acute Lower Motor Neuron facial nerve paralysis (>80%) causing an inability to control facial muscles on the affected side. The later one is sixth nerve palsy, (the abducens nerve), which is responsible for triggering contraction of the lateral rectus muscle to abduct (i.e., turn out) the eye resulting in double vision on the affected side. In recent times, we have found to our amazement, rapid restoration of normalcy within a few hours to a few days, of Cranial Nerve palsies in diabetic subjects at our centre. We are presenting a group of cases having Type2DM over different time periods from 6 to 20 years and those who suddenly suffered facial nerve palsy and they came to VHSDRC for treatment. They were started on the new modality called the Dynamic Acupuncture Mediated Meta-physical Energy Therapy (DAMM Therapy), to recover from the facial palsy. The DAMM therapy is a unique novel way of infusing and transferring healing energy from the therapist to the patient. Within 2 - 7 sittings of DAMM therapy patients showed 75% - 100% improvement in their clinical condition.

关键词： Bell’s palsy facial palsy Mononeuropathy Cranial Nerve palsy Microangiopathy Dynamic Acupuncture Mediated Metaphysical Energy Therapy (DAMM Therapy)

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facial nerve hemangiomas: A review

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Journal of Otology 2012年第1期7卷 28-30页

作者： SONG Zhi-yao LI Jian-dong Department of Otorhinolaryngology Capital Medical University Affiliated Beijing Shijitan HospitalHealth Science CenterPeking University100038 BeijingChina

facial nerve hemangiomas are rare benign vascular tumors with primary symptoms including progressive facial nerve palsy and hearing loss. They can involve various segments of the facial nerve, especially the geniculate ganglion （G.G.）. Preoperative MRI and CT imagining is of great importance for early diagnosis of such lesions. The most accepted treatment for facial nerve hemangiomas is surgical excisiont and the type of approach depends on tumor location, preoperative bearing level and tumor size. In consideration of the difficulties in differential diagnosis, otologists should pay attention to avoid missed or incorrect diagnosis in hemangiomas of facial nerve.

关键词： facial nerve hemangioma facial palsy

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