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Early Diagnosis of Lung Tumors for Extending Patients’ Life Using Deep Neural Networks

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Computers, Materials & Continua 2023年第7期76卷 993-1007页

作者： A.Manju R.Kaladevi Shanmugasundaram Hariharan Shih-Yu Chen Vinay Kukreja Pradip Kumar Sharma Fayez Alqahtani Amr Tolba Jin Wang Department of Computer Science and Engineering SRM Institute of Science and TechnologyRamapuramChennaiIndia Department of Computer Science and Engineering Saveetha Engineering CollegeChennaiIndia Department of Computer Science and Engineering Vardhaman College of EngineeringHyderabadIndia Department of Computer Science and Information Engineering National Yunlin University of Science and TechnologyYunlin 64002Taiwan Intelligence Recognition Industry Service Research Center National Yunlin University of Science and TechnologyYunlin 64002Taiwan Chitkara University Institute of Engineering and Technology Chitkara UniversityPunjabIndia Department of Computing Science University of AberdeenAberdeenUK Software Engineering Department College of Computer and Information SciencesKing Saud UniversityRiyadh 12372Saudi Arabia Computer Science Department Community CollegeKing Saud UniversityRiyadh 11437Saudi Arabia School of Computer&Communication Engineering Changsha University of Science&TechnologyChangshaChina

The medical community has more concern on lung cancer *** experts’physical segmentation of lung cancers is time-consuming and needs to be *** research study’s objective is to diagnose lung tumors at an early stage to extend the life of humans using deep learning ***-Aided Diagnostic(CAD)system aids in the diagnosis and shortens the time necessary to detect the tumor *** application of Deep Neural Networks(DNN)has also been exhibited as an excellent and effective method in classification and segmentation *** research aims to separate lung cancers from images of Magnetic Resonance Imaging(MRI)with threshold *** Honey hook process categorizes lung cancer based on characteristics retrieved using several *** this principle,the work presents a solution for image compression utilizing a Deep Wave Auto-Encoder(DWAE).The combination of the two approaches significantly reduces the overall size of the feature set required for any future classification process performed using *** proposed DWAE-DNN image classifier is applied to a lung imaging dataset with Radial Basis Function(RBF)*** study reported promising results with an accuracy of 97.34%,whereas using the Decision Tree(DT)classifier has an accuracy of 94.24%.The proposed approach(DWAE-DNN)is found to classify the images with an accuracy of 98.67%,either as malignant or normal *** contrast to the accuracy requirements,the work also uses the benchmark standards like specificity,sensitivity,and precision to evaluate the efficiency of the *** is found from an investigation that the DT classifier provides the maximum performance in the DWAE-DNN depending on the network’s performance on image testing,as shown by the data acquired by the categorizers themselves.

关键词： Lung tumor deep wave auto encoder decision tree classifier deep neural networks extraction techniques

Recent trends in extraction,identification and quantification methods of Centella asiatica phytochemicals with potential applications in food industry and therapeutic relevance:A review

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Food Bioscience 2022年第5期49卷 282-306页

作者： Soubhagya Tripathy Deepak Kumar Verma Mamta Thakur Nishant Chakravorty Smita Singh Prem Prakash Srivastav Agricultural and Food Engineering Department Indian Institute of Technology KharagpurKharagpur721302West BengalIndia Department of Food Technology School of SciencesITM UniversityGwalior474001Madhya PradeshIndia School of Medical Science and Technology Indian Institute of Technology Kharagpur721302West BengalIndia Department of Nutrition and Dietetics University Institute of Applied Health SciencesChandigarh UniversityChandigarh140413PunjabIndia

Centella asiatica,a pre-historically utilized medicinal herb that is well recognized as a traditional phytotherapeutic substance for treating a variety of ***,its phytochemicals use as a functional component in food and beverage has recently attracted the attentions of food researchers and *** possesses pharmacological value due to the presence of phytochemicals like flavonoids and terpenoids,mainly asiatic acid,asiaticoside,and *** role as a functional component in developing various processed food products and packaging films is continuously being *** improves the micronutrient profile and antioxidant potential of developed food products like noodles,chocolates,soups,pasta,***,comprehensive scientific validation based on clinical trials is inadequate,which impede the perception of health benefits and nutritional importance of *** rich food ***,there is a need to extensively examine the composition of *** active compounds in order to maximise its application in the food processing and preservation ***,the goal of this paper is to investigate into the existing information on the extraction,identification,and quantification of *** phytochemicals,as well as to explore their biological *** potential of *** for developing functional foods and beverages,as well as their processing and preservation to improve human health,is also highlighted.

关键词： Centella asiatica Asiatic acid Phytochemicals extraction techniques Food applications Anti-cancerous activity Antidiabetic effect

Citrus reticulata Blanco (the common mandarin) fruit:An updated review of its bioactive,extraction types,food quality,therapeutic merits,and bio-waste valorization practices to maximize its economic value

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Food Bioscience 2022年第3期47卷 67-80页

作者： Mohamed Shorbagi Nesrin M.Fayek Ping Shao Mohamed A.Farag Department of Special Chemistry Faculty of ScienceBenha UniversityAl Qalyubia GovernorateEgypt Pharmacognosy Department College of PharmacyCairo UniversityKasr El Aini st.11562CairoEgypt College of Food Science and Technology Zhejiang University of TechnologyZhejiangHangzhou310014PR China

Fruits are regarded as the richest dietary sources of polyphenols,carotenoids,terpenoids,and limonoids,making them highly desired prospects for the functional food *** waste that remains after fruit processing is also regarded as a valuable source of value-added phytochemicals.A comprehensive analysis of mandarin composition as a determinant of fruit functional properties,health benefits,and valorization into useful products is represented together with the effect of different processes such as light,wax coating,auxin addition,ozone treatment,and ethylene *** reviewing evidence is an essential precondition for improving the selling market of mandarin and highlighting its waste valorization potential and its incorporation into useful products produced by pharmaceutical *** this study,the phytochemical and biological reports presented to emphasize the needed priority for agricultural techniques to provide a certain mandarin product or *** addition,the paper summarizes the optimum conditions applied for the updated extraction techniques for phenolic acids,flavonoids,and oils at a commercial scale from mandarin peels and to enhance its global marketing.A brief representation is given towards potential mandarin patents and the valorization of its bio-waste fruits into commercial products of added *** review can guide researchers to produce future potentially marketed functional food enriched with mandarin extracts and/or bioactives.

关键词： Citrus reticulata Phytochemical composition Biological effects Waste valorization extraction techniques Processing effect

A review on the extraction and separation of andrographolide from Andrographis paniculata:extraction selectivity,current challenges and strategies

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Traditional Medicine Research 2023年第7期8卷 11-23页

作者： Di Liang Wei-Mei Zhang Xu Liang Hong-Yue Tian Xue-Min Zhang Xia Li Wen-Yuan Gao Tianjin Key Laboratory for Advanced Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin 300193China Key Laboratory of Advanced Chinese Medicine Resources Research Enterprises Tianjin 300402China College of Pharmacy Qinghai Minzu UniversityQinghai 810007China

Andrographolide is the main active ingredient of Andrographis paniculata(Burm.f.)Nees,known as“natural antibiotic”.Here,for the purpose of discovering a more efficient,low-cost extraction and separation method,the research status of andrographolide was *** present,researches only take extraction rate as the only index to optimize extraction parameters,but ignores the importance of extraction *** is usually meaningless to blindly pursue the extraction rate without considering the difficulty and cost of subsequent ***,factors affecting extraction selectivity such as solvent choice,temperature and physicochemical effects caused by extraction technique itself,are first *** extraction techniques for andrographolide were discussed by comparing the selectivity,efficiency and cost of *** separation procedures of andrographolide such as decolorization,impurity removal,crystallization,membrane separation,solid-phase extraction and partition chromatography and their challenges and possible strategies are also *** is hoped that this review can provide guidance for researchers who are committed to advancing the field of andrographolide extraction and purification.

关键词： andrographolide extraction techniques extraction selectivity separation

Research Progress of Total Flavonoids from Plants in ***

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Agricultural Biotechnology 2023年第6期12卷 12-18页

作者： Jiemei LIANG Li LI Lanlan FAN Hua ZHU Qiaowen ZHOU Mingjuan HUANG Qiulian WU Xue WANG Guangxi University of Chinese Medicine Nanning 530200China Guangxi Key Laboratory of Zhuang and Yao Medicine Nanning 530200China

*** is one of the important medicinal plants in traditional *** are 41 genera,6 genera of which are produced in China,mainly distributed in Southwest China,South China and Central South *** are many kinds of plants in this family,and 22 species can be used as Chinese medicinal materials in *** branches and leaves of *** are rich in flavonoids,alkaloids,terpenoids,polysaccharides,organic acids and other functional substances,among which flavonoids are one of the important chemical components to exert pharmacological activity,and play an important role in hypoglycemic,lipid-lowering,anti-inflammatory,anti-tumor,anti-oxidation,anti-osteoporosis and so *** this paper,the chemical composition,extraction method,component analysis and pharmacological action of flavonoids in *** plants were reviewed,in order to provide scientific reference for further development and clinical application of flavonoids in *** plants.

关键词： Trib.Lorantheae Total flavonoids extraction techniques Analytic procedure Pharmacological effect