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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第1期14卷 76-82页

作者： Wen-fang YANG Fei HAN Xiao-hui ZHANG Ping ZHANG Jiang-hua CHEN Kidney Disease Center the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 China

The diagnosis of extra-pulmonary tuberculosis(TB) seems relatively difficult due to the absence of specific symptoms and signs in patients on peritoneal dialysis or *** report four cases of extra-pulmonary tuberculosis on dialysis,with two cases on peritoneal dialysis and two cases on *** presentations,therapy,and outcomes of TB infection in these patients were ***,the English literature published in the PubMed database associating extra-pulmonary tuberculosis on dialysis over the last three decades is reviewed.A total of 61 studies containing 70 cases were *** most common primary disease was diabetic nephropathy(22.86%,16/70).The peritoneum(31.42%,22/70),bone(21.42%,15/70),and lymph node(20%,14/70) were the most frequently *** organ infection was common(90%,63/70).Fever(58.57%,41/70),pain(35.71%,25/70),and enlarged lymph node(20%,14/70) were the most common ***(67.14%,47/70) and culture(40%,28/70) provided most reliable methods for clear diagnosis of *** combined treatment of isoniazid,rifampicin,pyrazinamide,and ethambutol(44.29%,31/70) was the most common *** majority of patients improved(82.86%,58/70);however,12 cases got worse(17.14%),with 10 of them dying(14.29%).Physicians should be aware of the non-specific symptoms and location of infection,and consider tuberculosis in their differential diagnoses in dialysis patients presenting with symptoms such as fever,pain,and weight loss.

关键词： extra-pulmonary tuberculosis End stage renal disease Dialysis

extra-pulmonary tuberculosis: Retrospective Review of 83 Confirmed Cases, Observed in Radiology in Lomé(TOGO)

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Open Journal of Radiology 2016年第1期6卷 49-55页

作者： Mazamaesso Tchaou Tchin Darre Komi Edem Mossi Lantam Sonhaye Mohaman Djibril Awereou Kotosso Lama Agoda-Koussema Komlan Adjenou Koffi N’Dakena Department of Radiology Sylvanus Olympio Teaching Hospital of Lomé Lomé Togo Department of Pathology Laboratory Sylvanus Olympio Teaching Hospital of Lomé Lomé Togo Department of Internal Medicine Sylvanus Olympio Teaching Hospital of Lomé Lomé Togo Department of Infectious and Tropical Diseases Sylvanus Olympio Teaching Hospital of Lomé Lomé Togo

Background: tuberculosis primarily affects lungs, but all organs may be affected. extra-pulmonary forms of tuberculosis cause a big public health problem as it is diagnosed late. This delay in diagnosis is not only due to the delay in the examination, but also due to difficulties related to extra-pulmonary tuberculosis diagnostic. Aim: To describe the different locations of extra-pulmonary tuberculosis and its aspects in Togo. Patients and Methods: A retrospective analysis of all extra-pulmonary tuberculosis cases diagnosed by imaging over five years (January 2010 to December 2015) was done. All the cases were confirmed either by direct examination of biological fluids or by histological analysis of biopsy and surgical samples or by culture on specific area. Data were collected from the Department of Radiology, from Microbiology Laboratory of the Pneumo-phthisiology unit and from Pathology Laboratory of Sylvanus Olympio Teaching Hospital of Lomé. Results: A total of 83 cases of extra-pulmonary tuberculosis had been taken into account: 45 men and 38 women, with a maximum number of cases (66.3%) in the age group between 20 to 40 years old. An HIV infection was known in 51 patients (61.4%). pulmonary damage was associated in 21 patients (25.3%). A total of 116 extra-pulmonary tuberculosis locations were recorded. Damages were pleural in 37.1% (43), ganglion in 24.1% (28), osteo-articular in 15.5% (18), abdominal in 12.9% (15), military represented 8.6% (10), a case of testicular damage, and a case of mammary tuberculosis. Conclusion: The medical scanning based on conventional radiography, ultrasonography and TDM is indispensable for the diagnosis and the care taking of extra-pulmonary tuberculosis since some locations may be confused with many other diseases and lead to misdiagnosis errors and delay the treatment.

关键词： extra-pulmonary tuberculosis Radiography Ultrasonography Computed Tomography Diagnostic Africa Togo

extra-pulmonary tuberculosis in the Uterine Cervix: A Case Report

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Case Reports in Clinical Medicine 2022年第10期11卷 409-413页

作者： Charles Lukanga Kimera Fredrick Sinyinza Linda Ndesipandula Lukolo Department of Maternal & Child Health Obstetrics & Gynaecology School of Medicine University of Namibia Windhoek Namibia Department of Maternal & Child Health Paediatrics School of Medicine University of Namibia Windhoek Namibia Department of Community and Family Medicine School of Medicine University of Namibia Windhoek Namibia

tuberculosis of the uterine cervix is grouped under genital tuberculosis. Other sites for genital tuberculosis include the Fallopian tubes and the endometrium. Genital tuberculosis and other types of tuberculosis outside the lungs are referred to as extra-pulmonary tuberculosis (EPTB). Genital tuberculosis presents with unspecific symptoms and signs;and because of this, most often, the diagnosis is made incidentally during investigations for other conditions that present with similar clinical pictures. Therefore, misdiagnosis and wrong treatment are not uncommon. We present a case of tuberculosis of the uterine cervix which was incidentally diagnosed when the patient was being investigated for cervical cancer, and successfully treated with a 6-months rifampicin regimen, 2RHZE/4HRE. Health providers have a duty to highly suspect tuberculosis of the cervix among women who present with abnormal vaginal discharge, abnormal vaginal bleeding and post-coital bleeding especially in countries where HIV and TB are endemic. If properly diagnosed and correctly treated, tuberculosis of the uterine cervix is curable.

关键词： tuberculosis extra-pulmonary tuberculosis Genital tuberculosis Post-Coital Bleeding Cervical tuberculosis

Isolated gallbladder tuberculosis mimicking acute cholecystitis:A case report

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World Journal of Gastrointestinal Surgery 2020年第3期12卷 123-128页

作者： Kai Siang Chan Vishal G Shelat Cher Heng Tan Yee Lin Tang Sameer P Junnarkar Kong Chian School of Medicine Nanyang Technological UniversitySingapore 308232Singapore Department of General Surgery Tan Tock Seng HospitalSingapore 308433Singapore Department of Diagnostic Radiology Tan Tock Seng HospitalSingapore 308433Singapore Department of Pathology Tan Tock Seng HospitalSingapore 308433Singapore

BACKGROUND Isolated tuberculosis of the gallbladder is extremely rare due to its intrinsic resistance to tuberculous *** are reports of gallbladder tuberculosis mimicking cholecystitis or ***,these presentations were *** diagnosis of gallbladder tuberculosis warrants the need for investigation of additional sites of inoculation and contact tracing of all tuberculosis *** tuberculosis is a rare entity but should be suspected in patients from endemic regions with risk factors such as underlying immunosuppression or history of *** SUMMARY We present a case of gallbladder tuberculosis presenting as acute cholecystitis.A 44-year-old Filipino lady presented with a 11-d history of right hypochondrium and epigastric pain which worsened after meals with no significant past medical *** underwent laparoscopic cholecystectomy on the presumptive diagnosis of acute cholecystitis and diagnosed as gallbladder tuberculosis after histopathological *** patient did not have features of pulmonary or systemic tuberculosis nor was she *** recovered *** was subsequently discharged and followed-up at a hospital in her home country due to financial and social *** Clinicians should have a high index of suspicion for patients in endemic regions presenting with cholecystitis.

关键词： Cholecystectomy Cholecystitis Gallbladder extra-pulmonary tuberculosis Case report

Primary Breast tuberculosis Mimicking Carcinomatous Mastitis: A Case Report

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Open Journal of Pathology 2021年第3期11卷 79-83页

作者： Zo Irène Raivoherivony Lalaina Nomenjanahary Fenohery Nalisoa Rakotondrainibe Nantenaina Soa Randrianjafisamindrakotroka Department of Pathology Joseph Ravoahangy Andrianavalona University Hospital Antananarivo Madagascar Department of Pathology Anosiala University Hospital Antananarivo Madagascar Department of Pathology Medical School of Antananarivo Antananarivo Madagascar

The breast is a rare localization of extra-pulmonary tuberculosis, even in highly endemic countries. It is most often primitive. The clinical and radiological features are sometimes misleading. It poses diagnostic problems especially with cancer. We report a case of breast tuberculosis having clinical and radiological presentations as a breast carcinoma. Through this observation and a review of the literature, we provide an update on the epidemiological characteristics and the means of diagnosis of this lesion. It was a 52-year-old woman with inflammatory lump of the left breast, adherent to the skin. Ultrasonography and mammography revealed a homogeneous, poorly demarcated nodule of approximately 4 cm of diameter, classified ACR4. Surgical excision was performed. The histological diagnosis was breast tuberculosis. The diagnosis of tuberculous mastitis is made on bacteriological and pathological examinations. Histological examination helps for diagnostic confirmation while excluding a malignant lesion of the breast.

关键词： Mastitis Breast Disease extra-pulmonary tuberculosis